Urinary Protein Profiles in Patients with Urothelial Bladder Tumours

1981 ◽  
Vol 53 (4) ◽  
pp. 324-329 ◽  
Author(s):  
L. HEMMINGSEN ◽  
F. RASMUSSEN ◽  
P. SKAARUP ◽  
H. WOLF
Keyword(s):  
Urinary Protein ◽  
Protein Profiles ◽  
Urothelial Bladder ◽  
Bladder Tumours

scholarly journals Isobaric tag for relative and absolute quantitation based quantitative proteomics reveals unique urinary protein profiles in patients with preeclampsia

2019 ◽  
Vol 23 (8) ◽  
pp. 5822-5826 ◽  
Author(s):  
Wenyan Ding ◽  
Bintao Qiu ◽  
David S. Cram ◽  
Xiuting Chen ◽  
Shengjie Li ◽  
...  
Keyword(s):  
Quantitative Proteomics ◽  
Urinary Protein ◽  
Protein Profiles ◽  
Absolute Quantitation ◽  
Isobaric Tag

scholarly journals Urinary protein profiles in ketorolac-associated acute kidney injury in patients undergoing orthopedic day surgery

2017 ◽  
Vol Volume 10 ◽  
pp. 269-274 ◽  
Author(s):  
Filippo Mariano ◽  
Chiara Cogno ◽  
Fulvia Giaretta ◽  
Ilaria Deambrosis ◽  
Simona Pozza ◽  
...  
Keyword(s):  
Acute Kidney Injury ◽  
Kidney Injury ◽  
Day Surgery ◽  
Urinary Protein ◽  
Protein Profiles

Urinary protein profiles after burn injury

Burns ◽  
1983 ◽  
Vol 9 (5) ◽  
pp. 339-349 ◽  
Author(s):  
H. Yu ◽  
E.H. Cooper ◽  
J.A.D. Settle ◽  
T. Meadows
Keyword(s):  
Burn Injury ◽  
Urinary Protein ◽  
Protein Profiles

Urinary Protein Profiles following Urography with Iothalamate

1987 ◽  
Vol 28 (3) ◽  
pp. 335-338 ◽  
Author(s):  
P. Skaarup ◽  
H. S. Thomsen
Keyword(s):  
Urinary Protein ◽  
Tubular Function ◽  
Protein Profiles

Urinary protein profiles (IgG, albumin, β2-microglobulin) following urography with iothalamate were investigated in 5 patients with functionally and morphologically normal kidneys. In 4 of 5 patients an increased clearance of at least one of the proteins was found indicating disturbance in both glomerular and tubular function and the change was transient (up to 6 days). Albustix was always negative.

Endocavitary Prophylaxis of Superficial Urothelial Bladder Tumours: New Compounds

2009 ◽  
Vol 76 (1) ◽  
pp. 1-9
Author(s):  
R. Bartoletti ◽  
T. Cai
Keyword(s):  
Urothelial Bladder ◽  
New Compounds ◽  
Bladder Tumours

Urinary Protein Profiles following Urography with Iothalamate

1987 ◽  
Vol 28 (3) ◽  
pp. 335-338
Author(s):  
P. Skaarup ◽  
Henrik S. Thomsen
Keyword(s):  
Urinary Protein ◽  
Protein Profiles

A clinicopathological and immunohistochemical study of non-urothelial bladder tumours

2019 ◽  
Vol 56 (3) ◽  
pp. 254 ◽  
Author(s):  
Avinash Gupta ◽  
Sukhpreet Kaur ◽  
HanniV Gulwani
Keyword(s):  
Immunohistochemical Study ◽  
Urothelial Bladder ◽  
Bladder Tumours

Bovine Papillomavirus Type 13 Expression in the Urothelial Bladder Tumours of Cattle

2015 ◽  
Vol 63 (6) ◽  
pp. 628-634 ◽  
Author(s):  
S. Roperto ◽  
V. Russo ◽  
L. Leonardi ◽  
M. Martano ◽  
F. Corrado ◽  
...  
Keyword(s):  
Bovine Papillomavirus ◽  
Urothelial Bladder ◽  
Bladder Tumours

scholarly journals PAK5 mediates cell: cell adhesion integrity via interaction with E-cadherin in bladder cancer cells

2017 ◽  
Vol 474 (8) ◽  
pp. 1333-1346 ◽  
Author(s):  
Ahmad Fahim Ismail ◽  
Sevil Oskay Halacli ◽  
Nouf Babteen ◽  
Mario De Piano ◽  
Tracey A. Martin ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Progression ◽  
Survival Rates ◽  
Invasive Disease ◽  
Cell Junctions ◽  
High Survival ◽  
Urothelial Bladder ◽  
Muscle Invasive ◽  
Bladder Tumours ◽  
E Cadherin

Urothelial bladder cancer is a major cause of morbidity and mortality worldwide, causing an estimated 150 000 deaths per year. Whilst non-muscle-invasive bladder tumours can be effectively treated, with high survival rates, many tumours recur, and some will progress to muscle-invasive disease with a much poorer long-term prognosis. Thus, there is a pressing need to understand the molecular transitions occurring within the progression of bladder cancer to an invasive disease. Tumour invasion is often associated with a down-regulation of E-cadherin expression concomitant with a suppression of cell:cell junctions, and decreased levels of E-cadherin expression have been reported in higher grade urothelial bladder tumours. We find that expression of E-cadherin in a panel of bladder cancer cell lines correlated with the presence of cell:cell junctions and the level of PAK5 expression. Interestingly, exogenous PAK5 has recently been described to be associated with cell:cell junctions and we now find that endogenous PAK5 is localised to cell junctions and interacts with an E-cadherin complex. Moreover, depletion of PAK5 expression significantly reduced junctional integrity. These data suggest a role for PAK5 in maintaining junctional stability and we find that, in both our own patient samples and a commercially available dataset, PAK5mRNA levels are reduced in human bladder cancer compared with normal controls. Taken together, the present study proposes that PAK5 expression levels could be used as a novel prognostic marker for bladder cancer progression.

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