Less weight gain and hypoglycaemia with once-daily insulin detemir than NPH insulin in intensification of insulin therapy in overweight Type 2 diabetes patients-The PREDICTIVE™ BMI clinical trial1

2008 ◽  
Vol 25 (8) ◽  
pp. 916-923 ◽  
Author(s):  
C. Fajardo Montañana ◽  
C. Hernández Herrero ◽  
M. Rivas Fernández
Keyword(s):  
Type 2 Diabetes ◽  
Weight Gain ◽  
Insulin Therapy ◽  
Insulin Detemir ◽  
Nph Insulin ◽  
Once Daily ◽  
Daily Insulin ◽  
Diabetes Patients

Comparison of once-daily insulin detemir with NPH insulin added to a regimen of oral antidiabetic drugs in poorly Controlled Type 2 Diabetes

2006 ◽  
Vol 28 (10) ◽  
pp. 1569-1581 ◽  
Author(s):  
Athena Philis-Tsimikas ◽  
Guillaume Charpentier ◽  
Per Clauson ◽  
Gabriela Martinez Ravn ◽  
Victor Lawrence Roberts ◽  
...  
Keyword(s):  
Type 2 Diabetes ◽  
Insulin Detemir ◽  
Antidiabetic Drugs ◽  
Oral Antidiabetic Drugs ◽  
Nph Insulin ◽  
Once Daily ◽  
Daily Insulin ◽  
Oral Antidiabetic

scholarly journals The Effect Of Diet Composition On Weight Gain in Obese, Type 2 Diabetes Patients Receiving Intensive Insulin Therapy

2015 ◽  
Vol 6 (2) ◽  
pp. 111-116
Author(s):  
Roland Villareal
Keyword(s):  
Type 2 Diabetes ◽  
Weight Gain ◽  
Insulin Therapy ◽  
Intensive Insulin Therapy ◽  
Diet Composition ◽  
High Carbohydrate ◽  
Total Calorie ◽  
Mufa Diet ◽  
Diabetes Patients

This study was conducted to contribute to the limiting existing body of literature about diet and prevention of weight gain when administering intensive insulin therapy.  The effects of a high- monounsaturated fatty acid (MUFA) diet compared with a conventional diabetic diet have not been studied in insulin treated patients.  A growing body of evidence assessed that diets rich in high-MUFA foods had similar glycemic results, as do low-fat, high carbohydrate diets.  However, a high-MUFA diet did not raise triglycerides as suspected.  Ros (2003) stated that high-MUFA energy controlled diets do not promote weight gain and are more acceptable for weight loss and/or maintenance. A MUFA diet can be used as an alternate to the conventional American Diabetic Association (ADA) diet when managing obese type 2 diabetes patients treated with intensive insulin therapy.  Dietary restriction to 1600 calories in diabetes patients on intensive insulin therapy decreased the A1C value by 1.3 points in the ADA group and 1.5 points in the MUFA group without weight gain and without additional insulin required.  In conclusion the total calorie count was more important for preventing weight gain and reducing the A1C in patients on intensive insulin therapy than was dietary composition.

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