scholarly journals Role of myosin heavy chain composition in kinetics of force development and relaxation in rat myocardium

1998 ◽  
Vol 513 (1) ◽  
pp. 171-183 ◽  
Author(s):  
Daniel P. Fitzsimons ◽  
Jitandrakumar R. Patel ◽  
Richard L. Moss
2007 ◽  
Vol 579 (1) ◽  
pp. 161-173 ◽  
Author(s):  
Julian E. Stelzer ◽  
Stacey L. Brickson ◽  
Matthew R. Locher ◽  
Richard L. Moss

2009 ◽  
Vol 54 (8) ◽  
pp. 783-789 ◽  
Author(s):  
Yoshiki Ohnuki ◽  
Nobuhiko Kawai ◽  
Eiji Tanaka ◽  
Geerling E.J. Langenbach ◽  
Kazuo Tanne ◽  
...  

1998 ◽  
Vol 21 (3) ◽  
pp. 375-389 ◽  
Author(s):  
Elena J. Grossman ◽  
Roland R. Roy ◽  
Robert J. Talmadge ◽  
Hui Zhong ◽  
V. Reggie Edgerton

2006 ◽  
Vol 43 (6) ◽  
pp. 881-889 ◽  
Author(s):  
C. M. Adreani ◽  
Z. B. Li ◽  
M. Lehar ◽  
L. L. Southwood ◽  
P. L. Habecker ◽  
...  

2015 ◽  
Vol 47 ◽  
pp. 102
Author(s):  
Michael T. Lane ◽  
Andrew C. Fry ◽  
Trent J. Herda ◽  
Joseph P. Weir ◽  
Ashley W. Herda

2000 ◽  
Vol 88 (2) ◽  
pp. 479-486 ◽  
Author(s):  
A. X. Bigard ◽  
H. Sanchez ◽  
O. Birot ◽  
B. Serrurier

This study investigated the effects of voluntary wheel running on the myosin heavy chain (MHC) composition of the soleus (Sol) and plantaris muscles (Pla) in rats developing under hypobaric choronic hypoxia (CH) conditions during 4 wk in comparison with those of control rats maintained under local barometric pressure conditions (C) or rats pair-fed an equivalent quantity of food to that consumed by CH animals (PF). Compared with C animals, sedentary rats subjected to CH conditions showed a significant decrease in type I MHC in Sol (−12%, P < 0.01). Although strongly decreased under hypoxia, spontaneous running activity increased the expression of type I MHC ( P < 0.01) so that no difference in the MHC profile of Sol was shown between CH active and C active rats. The MHC distribution in Sol of PF rats was not significantly different from that found in C animals. CH resulted in a significant decrease in type I ( P < 0.01) and type IIA ( P < 0.005) MHC, concomitant with an increase in type IIB MHC in Pla ( P < 0.001), compared with C and PF animals. In contrast to results in Sol muscle, this slow-to-fast shift in the MHC profile was unaffected by spontaneous running activity. These results suggest that running exercise suppresses the hypoxia-induced slow-to-fast transition in the MHC expression in Sol muscles only. The hypoxia-induced decrease in food intake has no major influence on MHC expression in developing rats.


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