scholarly journals Four novel myosin heavy chain transcripts define a molecular basis for muscle fibre types inRanapipiens

1998 ◽  
Vol 508 (3) ◽  
pp. 667-680 ◽  
Author(s):  
Gordon J. Lutz ◽  
Denise B. Cuizon ◽  
Allen F. Ryan ◽  
Richard L. Lieber
1990 ◽  
Vol 68 (5) ◽  
pp. 596-602 ◽  
Author(s):  
David J. Parry ◽  
Ross S. Wilkinson

The distribution of fibre types in the tibialis anterior (TA) muscle of adult mice was examined by means of an immuno-histochemical approach, using monoclonal antibodies that recognize different myosin heavy chain isoforms. As has been reported previously, the superficial portion of TA contains almost exclusively type IIB fibres and is almost entirely glycolytic in nature. Following section of the lateral popliteal nerve and rotation of the proximal stomp to prevent rematching, it was found that the original pattern was virtually restored within 2 months. One possible explanation for this observation is that the activity pattern of peripheral and deep muscle fibres differs and that this aids in specification of muscle fibre type. Alternatively, the muscle fibres of the superficial portion of TA may be inherently resistant to an alteration of their phenotype with regard to expression of myosin heavy chain.Key words: myosin heavy chain, immunohistochemistry, plasticity, self-reinnervation, fibre types.


animal ◽  
2020 ◽  
Vol 14 (6) ◽  
pp. 1204-1212 ◽  
Author(s):  
A. Listrat ◽  
M. Gagaoua ◽  
J. Normand ◽  
D.J. Andueza ◽  
D. Gruffat ◽  
...  

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