Relationship of ATP Turnover, Polyphosphoinositide Metabolism, and Protein Phosphorylation in Sciatic Nerve and Derived Peripheral Myelin Subfractions from Normal and Streptozotocin Diabetic Rats

1989 ◽  
Vol 52 (3) ◽  
pp. 921-932 ◽  
Author(s):  
Joan M. Lowery ◽  
Liliana N. Berti-Mattera ◽  
Xi Zhu ◽  
Richard G. Peterson ◽  
Joseph Eichberg
Diabetes ◽  
1989 ◽  
Vol 38 (3) ◽  
pp. 373-378 ◽  
Author(s):  
L. N. Berti-Mattera ◽  
J. Lowery ◽  
S. F. Day ◽  
R. G. Peterson ◽  
J. Eichberg

1983 ◽  
Vol 210 (3) ◽  
pp. 775-781 ◽  
Author(s):  
K R W Gillon ◽  
J N Hawthorne

myo-Inositol transport by a viable rat sciatic-nerve preparation is described. Such ‘endoneurial’ nerve preparations accumulated myo-inositol by an energy-dependent saturable system. Streptozotocin-diabetes reduced myo-inositol transport into sciatic nerve by approx. 40%. Elevated medium glucose concentration reduced myo-inositol transport into control nerves to a similar extent. Fructose and sorbitol did not inhibit myo-inositol transport. Inclusion of an aldose reductase inhibitor in the medium counteracted the reduced myo-inositol transport caused by elevated glucose concentration. The importance of these results to the problem of diabetic neuropathy is discussed.


Pharmacology ◽  
1990 ◽  
Vol 40 (2) ◽  
pp. 110-121 ◽  
Author(s):  
Penelope A. Longhurst ◽  
Jianshe Kang ◽  
Alan J. Wein ◽  
Robert M. Levin

1988 ◽  
Vol 20 (11) ◽  
pp. 717-718 ◽  
Author(s):  
M. Sonobe ◽  
H. Yasuda ◽  
I. Hatanaka ◽  
M. Terada ◽  
M. Yamashita ◽  
...  

1999 ◽  
Vol 163 (1) ◽  
pp. 17-24 ◽  
Author(s):  
Kevin C. Dines ◽  
Nigel A. Calcutt ◽  
Kennette D. Nunag ◽  
Andrew P. Mizisin ◽  
Michael W. Kalichman

Diabetes ◽  
1989 ◽  
Vol 38 (3) ◽  
pp. 373-378 ◽  
Author(s):  
L. N. Berti-Mattera ◽  
J. Lowery ◽  
S.-F. Day ◽  
R. G. Peterson ◽  
J. Eichberg

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