Decreased Long-Chain Fatty Acyl CoA Elongation Activity in Quaking and Jimpy Mouse Brain: Deficiency in One Enzyme or Multiple Enzyme Activities?

1991 ◽  
Vol 57 (1) ◽  
pp. 140-146 ◽  
Author(s):  
S. K. Suneja ◽  
M. N. Nagi ◽  
L. Cook ◽  
D. L. Cinti
Keyword(s):  
Mouse Brain ◽  
Enzyme Activities ◽  
Fatty Acyl ◽  
Jimpy Mouse ◽  
Long Chain ◽  
Elongation Activity

A Ratiometric Fluorescent Biosensor Reveals Dynamic Regulation of Long‐Chain Fatty Acyl‐CoA Esters Metabolism

2021 ◽  
Author(s):  
Jing Wang ◽  
Weibo Wang ◽  
Qingpeng Wei ◽  
Jiayuan Zhang ◽  
Meiqi Zhang ◽  
...  
Keyword(s):  
Fatty Acyl ◽  
Dynamic Regulation ◽  
Fluorescent Biosensor ◽  
Long Chain

scholarly journals Utility of measuring very long-chain fatty-acyl carnitines in dried blood spots for newborn screening of X-linked Adrenoleukodystrophy

2021 ◽  
Vol 26 ◽  
pp. 100720
Author(s):  
Archana Natarajan ◽  
Rita Christopher ◽  
Shruti V. Palakuzhiyil ◽  
Sadanandavalli Retnaswami Chandra
Keyword(s):  
Newborn Screening ◽  
Dried Blood Spots ◽  
Fatty Acyl ◽  
Blood Spots ◽  
Long Chain

Long chain fatty acyl-CoA modulation of H2O2 release at mitochondrial complex I

2008 ◽  
Vol 40 (1) ◽  
pp. 9-18 ◽  
Author(s):  
Silvia Bortolami ◽  
Evelin Comelato ◽  
Franco Zoccarato ◽  
Adolfo Alexandre ◽  
Lucia Cavallini
Keyword(s):  
Complex I ◽  
Fatty Acyl ◽  
Mitochondrial Complex I ◽  
Mitochondrial Complex ◽  
Long Chain

scholarly journals Effect of long-chain fatty acyl-CoA on mitochondrial and cytosolic ATP/ADP ratios in the intact liver cell

1984 ◽  
Vol 220 (2) ◽  
pp. 371-376 ◽  
Author(s):  
S Soboll ◽  
H J Seitz ◽  
H Sies ◽  
B Ziegler ◽  
R Scholz
Keyword(s):  
Liver Cell ◽  
Adenine Nucleotide ◽  
Intact Cell ◽  
Inhibitory Effect ◽  
Fatty Acyl ◽  
Fed State ◽  
Physiological Relevance ◽  
Chain Acyl ◽  
Long Chain

The effect of long-chain acyl-CoA on subcellular adenine nucleotide systems was studied in the intact liver cell. Long-chain acyl-CoA content was varied by varying the nutritional state (fed and starved states) or by addition of oleate. Starvation led to an increase in the mitochondrial and a decrease in the cytosolic ATP/ADP ratio in liver both in vivo and in the isolated perfused organ as compared with the fed state. The changes were reversed on re-feeding glucose in liver in vivo or on infusion of substrates (glucose, glycerol) in the perfused liver, respectively. Similar changes in mitochondrial and cytosolic ATP/ADP ratios occurred on addition of oleate, but, importantly, not with a short-chain fatty acid such as octanoate. It is concluded that long-chain acyl-CoA exerts an inhibitory effect on mitochondrial adenine nucleotide translocation in the intact cell, as was previously postulated in the literature from data obtained with isolated mitochondria. The physiological relevance with respect to pyruvate metabolism, i.e. regulation of pyruvate carboxylase and pyruvate dehydrogenase by the mitochondrial ATP/ADP ratio, is discussed.

scholarly journals HDAC8 Catalyzes the Hydrolysis of Long Chain Fatty Acyl Lysine

2016 ◽  
Vol 11 (10) ◽  
pp. 2685-2692 ◽  
Author(s):  
Pornpun Aramsangtienchai ◽  
Nicole A. Spiegelman ◽  
Bin He ◽  
Seth P. Miller ◽  
Lunzhi Dai ◽  
...  
Keyword(s):  
Fatty Acyl ◽  
Hydrolysis Of ◽  
Long Chain

scholarly journals Localization of adipocyte long-chain fatty acyl-CoA synthetase at the plasma membrane

1999 ◽  
Vol 40 (5) ◽  
pp. 881-892 ◽  
Author(s):  
Christina E. Gargiulo ◽  
Sarah M. Stuhlsatz-Krouper ◽  
Jean E. Schaffer
Keyword(s):  
Plasma Membrane ◽  
Fatty Acyl ◽  
Long Chain
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