scholarly journals Determination of Acetylcholine Release in the Striatum of Anesthetized Rats Using In Vivo Microdialysis and a Radioimmunoassay

1991 ◽  
Vol 57 (3) ◽  
pp. 882-887 ◽  
Author(s):  
Koichiro Kawashima ◽  
Toru Hayakawa ◽  
Yuko Kashima ◽  
Takeshi Suzuki ◽  
Kazuko Fujimoto ◽  
...  
2002 ◽  
Vol 40 (3) ◽  
pp. 269-275 ◽  
Author(s):  
Angelina Rakovska ◽  
Janos P Kiss ◽  
Peter Raichev ◽  
Maria Lazarova ◽  
Reni Kalfin ◽  
...  

2001 ◽  
Vol 56 (6) ◽  
pp. 593-597 ◽  
Author(s):  
Akira Nakamura ◽  
Yusuke Suzuki ◽  
Hiroyuki Umegaki ◽  
Hiroyuki Ikari ◽  
Toshihisa Tajima ◽  
...  

2001 ◽  
Vol 120 (5) ◽  
pp. A289
Author(s):  
Shigeru Ueki ◽  
Masayuki Ogishima ◽  
Raita Higashino ◽  
Tomoyuki Yoneta ◽  
Tadashi Kurimoto

2002 ◽  
Vol 282 (6) ◽  
pp. C1423-C1431 ◽  
Author(s):  
Barbara R. Grubb ◽  
James L. Chadburn ◽  
Richard C. Boucher

Airway surface liquid (ASL) contains substances important in mucociliary clearance and airway defense. Little is known about substance concentrations in ASL because of its small volume and sampling difficulties. We used in vivo microdialysis (IVMD) to sample liquid lining the nasal cavity without net volume removal and incorporated into IVMD a potential difference (PD) electrode to assess airway integrity. The cystic fibrosis (CF) mouse nasal epithelia exhibit ion transport defects identical to those in CF human airways and, thus, are a good model for CF disease. We determined that nasal liquid [Na+] (107 ± 4 mM normal; 111 ± 9 mM CF) and [Cl−] (120 ± 6 mM normal; 122 ± 4 mM CF) did not differ between genotypes. The nasal liquid [K+] (8.7 ± 0.4 mM) was significantly less in normal than in CF mice (16.6 ± 4 mM). IVMD accurately samples nasal liquid for ionic composition. The ionic composition of nasal liquid in the normal and CF mice is similar.


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