The Influence of Food Temperature on Postprandial Blood Pressure Reduction and Its Relation to Substance-P in Healthy Elderly Subjects

The objective of the present study was to determine the comparative hypotensive responses to drinks containing predominantly fat and carbohydrate (CHO) in healthy elderly subjects. Using a randomised, cross-over study, the participants, twelve elderly subjects, six of them female (72·2 (sd 5·7) years), were investigated. On three separate days, blood pressure (BP) and heart rate were measured following ingestion of 300ml drinks containing: (1) CHO (75g glucose and 93g Polyjoule (CHO polymer) providing 2732kJ (653kcal)); (2) 88% fat (cream blended with milk providing 2732kJ (653kcal)); (3) water. Systolic BP decreased following the CHO drink (P<0·001) and the high-fat drink (P<0·001) but not water; there was no difference in the magnitude of the decrease between the CHO drink and the drink containing fat (13·4v. 15·6mmHg). However, the onset of the fall was slower after the fat-containing drink (13·0v. 26·5min (P=0·01); area under the curve for 0–30min for CHO drink −6·5v. fat-containing drink 125·4 mmHg×min (P=0·043)). We conclude that ingestion of a high-fat drink results in a comparable fall in BP to a CHO drink although the onset is relatively slower. These observations may have implications for the management of postprandial hypotension.

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Sympathetic overactivity due to sleep fragmentation is associated with elevated diurnal systolic blood pressure in healthy elderly subjects: the PROOF-SYNAPSE study

European Heart Journal ◽

10.1093/eurheartj/eht208 ◽

2013 ◽

Vol 34 (28) ◽

pp. 2122-2131 ◽

Cited By ~ 63

Author(s):

F. Chouchou ◽

V. Pichot ◽

J.L. Pépin ◽

R. Tamisier ◽

S. Celle ◽

...

Keyword(s):

Blood Pressure ◽

Systolic Blood Pressure ◽

Sleep Fragmentation ◽

Elderly Subjects ◽

Sympathetic Overactivity ◽

Healthy Elderly ◽

Healthy Elderly Subjects

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Blood pressure responses in healthy older people to 50 g carbohydrate drinks with differing glycaemic effects

British Journal Of Nutrition ◽

10.1079/bjn20041193 ◽

2004 ◽

Vol 92 (2) ◽

pp. 335-340 ◽

Cited By ~ 23

Author(s):

Renuka Visvanathan ◽

Richard Chen ◽

Michael Horowitz ◽

Ian Chapman

Keyword(s):

Blood Pressure ◽

Cardiovascular Response ◽

Blood Pressure Response ◽

Surrogate Marker ◽

Elderly Subjects ◽

Glucose Levels ◽

Healthy Elderly ◽

Cherry Juice ◽

Blood Pressure Responses ◽

Healthy Elderly Subjects

The aim of the present study was to determine the effects on blood pressure response of 50 g carbohydrate drinks with differing glycaemic effects in ten healthy elderly subjects (age >65 years; randomized crossover design). Systolic (SBP), diastolic (DBP) and mean arterial (MAP) blood pressure, heart rate and plasma glucose levels were determined following ingestion of equal volumes (379 ml) of water and 50 g carbohydrate drinks with differing reported glycaemic indices (GI) (surrogate marker for glycaemic effect): (1) low-GI: Apple & Cherry Juice; (2) intermediate-GI: Fanta Orange; (3) high-glucose. Glucose (SBP and DBP P<0·001; MAP P=0·005) and Fanta Orange (SBP P=0·005; DBP and MAP P<0·001) ingestion caused a significant decrease in BP whilst blood pressure increased (SBP P=0·008; MAP P=0·005) from baseline following Apple & Cherry Juice ingestion. Water had no significant effect on postprandial blood pressure. Fanta Orange and Apple & Cherry Juice caused similar (P=0·679) glycaemic effects, which were significantly greater than water, but lower than glucose (P<0·001). There was no significant correlation between the glycaemic effect of the carbohydrate drinks and there was no change in blood pressure from baseline (SBP r −0·123, P=0·509; DBP r −0·051, P=0·784; MAP r −0·069, P=0·712). Apple & Cherry Juice and Fanta Orange had similar glycaemic effects, but differing effects on blood pressure. Therefore, it is unlikely that the glycaemic effect of a drink can be used to predict the subsequent cardiovascular response.

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