OXIDATIVE STRESS AND MULTI-ORGAN FAILURE IN HOSPITALIZED ELDERLY PEOPLE

Abstract Background Physical restraint (PR) is a routine care measure in many hospital wards to ensure patient safety. However, it is associated with many different professional, legal, and ethical challenges. Some guidelines and principles have been developed in some countries for appropriate PR use. The present study aimed to explore the principles of PR use for hospitalized elderly people. Methods This was an integrative review. For data collection, a literature search was conducted in Persian and English databases, namely Magiran, Scientific Information Database (SID), Scopus, Google Scholar, Web of Science, and PubMed as well as the websites of healthcare organizations and associations. Eligibility criteria were publication in English or Persian between January 1, 2010, and January 1, 2021, and description of the principles of PR use for hospitalized elderly people. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement was used for document screening and selection, while the critical appraisal tools of the Joanna Briggs Institute (JBI) and the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument were used for quality appraisal. The data were analyzed through constant comparison. Results Primarily, 772 records were retrieved, while only twenty were eligible for the study. The principles of PR use for hospitalized elderly people were categorized into six main categories, namely principles of education for PR use, principles of decision making for PR use, principles of implementing the PR procedure, principles of monitoring patients with PR, principles of PR use documentation, and principles of PR management. Conclusion PR should be used only by trained healthcare providers, with the consent of patient or his/her family members, with standard devices and safe techniques, based on clear guidelines, and under close managerial supervision. Moreover, elderly people with PR should continuously be monitored for any PR-related complications. The findings of the present study can be used for developing clear PR-related guidelines.

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Simultaneous Occurrence of Choriocarcinoma in an Infant and Mother

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18041934 ◽

2021 ◽

Vol 18 (4) ◽

pp. 1934

Author(s):

Małgorzata Rzanny-Owczarzak ◽

Joanna Sawicka-Metkowska ◽

Katarzyna Jończyk-Potoczna ◽

Ewelina Gowin ◽

Patrycja Sosnowska-Sienkiewicz ◽

...

Keyword(s):

Rare Disease ◽

Organ Failure ◽

Liver Tumor ◽

Serum Levels ◽

Simultaneous Occurrence ◽

Positive History ◽

Multi Organ Failure ◽

History Of

Infantile choriocarcinoma is an extremely rare disease. We present a case study of a 1-month-old male with choriocarcinoma diagnosed simultaneously with his mother. On admission to hospital, the disease was very advanced and massive progression and multi-organ failure caused the death of the patient despite the implemented treatment. It was too late to save the child’s life, but early enough to save his mother. The authors believe that the serum levels of hCG should be determined in every newborn with anemia and liver tumor, especially when the mother has a positive history of miscarriage.

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Oxidative stress may be involved in distant organ failure in tourniquet shock model mice

Legal Medicine ◽

10.1016/j.legalmed.2013.11.004 ◽

2014 ◽

Vol 16 (2) ◽

pp. 70-75 ◽

Cited By ~ 7

Author(s):

Rie Nishikata ◽

Naho Kato ◽

Kouichi Hiraiwa

Keyword(s):

Oxidative Stress ◽

Organ Failure ◽

Shock Model ◽

Tourniquet Shock ◽

Distant Organ

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MECHANISMS FOR BLOCKADE OF IN VIVO ACTIVATOR PRODUCTION IN THE ISCHEMIC INTESTINE AND MULTI-ORGAN FAILURE

Shock ◽

10.1097/00024382-200014050-00005 ◽

2000 ◽

Vol 14 (5) ◽

pp. 522-527 ◽

Cited By ~ 32

Author(s):

Hiroshi Mitsuoka ◽

Geert W. Schmid-Schönbein

Keyword(s):

Organ Failure ◽

Multi Organ Failure ◽

Ischemic Intestine

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Multi-organ failure in adult onset Still’s disease: a septic disguise

Clinical Rheumatology ◽

10.1007/s10067-008-1010-1 ◽

2008 ◽

Vol 28 (S1) ◽

pp. 3-6 ◽

Cited By ~ 10

Author(s):

Paul R. J. Ames ◽

Emily Walker ◽

Darren Aw ◽

David Marshall ◽

Francois de Villiers ◽

...

Keyword(s):

Organ Failure ◽

Adult Onset Still’S Disease ◽

Adult Onset ◽

Still’S Disease ◽

Still's Disease ◽

Multi Organ Failure ◽

Adult Onset Still's Disease

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Pathophysiology of Hemorrhage as It Relates to the Warfighter

Physiology ◽

10.1152/physiol.00028.2021 ◽

2022 ◽

Author(s):

Carmen Hinojosa-Laborde ◽

Ian L. Hudson ◽

Evan Ross ◽

Lusha Xiang ◽

Kathy L. Ryan

Keyword(s):

Blood Transfusion ◽

Organ Failure ◽

Oxygen Delivery ◽

Multi Organ Failure ◽

Care Situation

Saving lives of wounded military Warfighters often depends on the ability to resolve or mitigate the pathophysiology of hemorrhage, specifically diminished oxygen delivery to vital organs that leads to multi-organ failure and death. However, caring for hemorrhaging patients on the battlefield presents unique challenges that extend beyond applying a tourniquet and giving a blood transfusion, especially when battlefield care must be provided for a prolonged period. This review will describe these challenges and potential strategies for treating hemorrhage on the battlefield in a prolonged casualty care situation.

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