Novel polymorphic short tandem repeat in the human alpha2 integrin gene promoter is associated with GPIa/IIa density on the platelet surface

2003 ◽  
Vol 1 ◽  
pp. P1762-P1762
Author(s):  
W. J. Sydor ◽  
M. Sanak ◽  
S. Bazan-Socha ◽  
A. Szczeklik ◽  
J. Musial
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Gene Promoter ◽  
Platelet Surface ◽  
Integrin Gene ◽  
Short Tandem

scholarly journals Short tandem repeat near hypoxia response element (HRE) instead of HRE genetic variants in promoter calcitonin receptor-like receptor (CRLR) gene as risk factor in severe preeclampsia: a preliminary study

2021 ◽  
Vol 14 (1) ◽  
Author(s):  
Herlambang ◽  
Amelia Dwi Fitri ◽  
Ahmad Syauqy ◽  
Yuwono ◽  
Anggelia Puspasari ◽  
...  
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Gene Promoter ◽  
Severe Preeclampsia ◽  
Calcitonin Receptor ◽  
Hypoxia Response Element ◽  
Response Element ◽  
Hypoxia Response ◽  
Control Study ◽  
Short Tandem

Abstract Objective Calcitonin receptor-like receptor (CRLR) regulates vasoconstriction and dilatation; the expression increases during hypoxia via activation of hypoxia response element (HRE) in CRLR gene promoter region. Variant in HRE, as well short tandem repeat (STR) variants near HRE in CRLR alters the gene expression. This study focused on a case–control study to investigate the expression of genetic typing CLRL promoter variant in pregnant women with severe preeclampsia and normal pregnancies, we also tried to describe interesting findings of the genetic expression in anemic patients in the severe preeclampsia group. Our aimed to observe the correlation of CRLR gene promoter variant and anemia in severe preeclampsia. Results There was no nucleotide variant in HRE; CACA box prior to HRE varied in length (15–24); CACA box with length > 20 was used as cut off point. Hb was lower in CACA box length ≥ 21 (10.33 ± 1.57) vs. < 21 (11.01 ± 1.67; p = 0.391). CACA box polymorphism and anemia were correlated in severe preeclampsia (p = 0.005) OR 0.038 (CI 0.003–0.544); not in normal (p = 0.069).

Analysis of short tandem repeat (STR) HUMVWA in the Spanish population

1994 ◽  
Vol 65 (3) ◽  
pp. 169-175 ◽  
Author(s):  
Jose A. Lorente ◽  
Miguel Lorente ◽  
Bruce Budowle ◽  
Mark R. Wilson ◽  
Enrique Villanueva
Keyword(s):  
Tandem Repeat ◽  
Short Tandem Repeat ◽  
Spanish Population ◽  
Short Tandem
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