Total paracentesis in cirrhotic patients with tense ascites and dilutional hyponatremia

1999 ◽  
Vol 94 (8) ◽  
pp. 2219-2223 ◽  
Author(s):  
Maria Carme Vila ◽  
Susanna Coll ◽  
Ricard Sola ◽  
Montserrat Andreu ◽  
Jordi Gana ◽  
...  
2001 ◽  
Vol 34 ◽  
pp. 61
Author(s):  
J.L. Poo ◽  
Y. Astorga ◽  
R.M. Munoz ◽  
J. Lizardi ◽  
S. Moran ◽  
...  

2004 ◽  
Vol 18 (2) ◽  
pp. 117-118 ◽  
Author(s):  
D Mohamed Babatin ◽  
Samuel S Lee

The paradox of dilutional hyponatremia, as described by Ovid two millennia ago, continues to apply to patients with advanced cirrhosis today: they have unremitting thirst despite vastly increased total body water. Hyponatremia of less than 130 mmol/L occurs in 30% of cirrhotic patients (1), and is mainly due to the reduced capacity of their kidneys to excrete free water.


2014 ◽  
Vol 2014 ◽  
pp. 1-4
Author(s):  
Guo Shen ◽  
Hainv Gao

Dilutional hyponatremia is common in decompensated cirrhosis and can be successfully treated by tolvaptan, a vasopressin V2-receptor antagonist. Data were lacking regarding the effects of tolvaptan on cirrhotic patients with a Child-Pugh score of >10 and a serum sodium concentration of <120 mmol/L. We report a case of forties man with a 20-year history of chronic hepatitis B presenting with yellow urine and skin. Laboratory tests demonstrated prolonged prothrombin time, markedly elevated total bilirubin, severe hyponatremia, and a Child-Pugh score of >10. The patient was diagnosed with dilutional hyponatremia and was treated with recommended dosage tolvaptan at first. The serum concentration of sodium recover but the patient felt obviously thirsty. As the dosage of tolvaptan was decreased accordingly from 15 mg to 5 mg, the patient still maintained the ideal concentration of serum sodium. This case emphasizes that cirrhotic patient with higher Child-Pugh scores and serum sodium concentration of <120 mmol/L can be treated with lower dose of tolvaptan.


2001 ◽  
Vol 120 (5) ◽  
pp. A77-A77
Author(s):  
D DELPHINE ◽  
F AGNESE ◽  
B NADINE ◽  
L OLIVIER ◽  
L HUBERT ◽  
...  

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