scholarly journals GENE-ENVIRONMENT INTERACTIONS IN HEREDITARY NONPOLYPOSIS COLORECTAL CANCER: POTENTIATION OF COLON CANCER RISK BY TOBACCO USE AND HMLH-1 MUTATIONS

2003 ◽  
Vol 98 ◽  
pp. S112 ◽  
Author(s):  
Ramesh Ashwathnarayan ◽  
Patrice Watson ◽  
Henry T. Lynch ◽  
Hemant K. Roy
1996 ◽  
Vol 110 (4) ◽  
pp. 1020-1027 ◽  
Author(s):  
HF Vasen ◽  
JT Wijnen ◽  
FH Menko ◽  
JH Kleibeuker ◽  
BG Taal ◽  
...  

2004 ◽  
Vol 18 (5) ◽  
pp. 319-320 ◽  
Author(s):  
Victor K Wong ◽  
Eric M Yoshida ◽  
Anthony G Ryan ◽  
Stephen GF Ho ◽  
Baljinder Salh

BACKGROUND:Hereditary nonpolyposis colorectal cancer (HNPCC) currently accounts for between 2% to 6% of all colorectal adenocarcinomas. Controversies exist regarding the current guidelines for colonoscopic screening for colon cancer.CASE REPORT:A case of colon cancer in a young Japanese man with a family history of colon cancer that did not meet the criteria for HNPCC is reported. A malignant pelvic mass discovered shortly before his 20th birthday prompted a colonoscopy. The findings at colonscopy determined that the patient and his family fulfilled the criteria of HNPCC.CONCLUSION:Before finding a pelvic mass metastatic from adenocarcinoma of the ascending colon, this patient was clearly outside of the current guidelines for HNPCC screening. It is suggested that in similar patients, even if they do not fulfill all the criteria for HNPCC, it would be appropriate to consider screening well before the recommended lower age.


2004 ◽  
Vol 127 (1) ◽  
pp. 17-25 ◽  
Author(s):  
Yvonne M.C. Hendriks ◽  
Anja Wagner ◽  
Hans Morreau ◽  
Fred Menko ◽  
Astrid Stormorken ◽  
...  

2005 ◽  
Vol 129 (2) ◽  
pp. 415-421 ◽  
Author(s):  
H HAMPEL ◽  
J STEPHENS ◽  
E PUKKALA ◽  
R SANKILA ◽  
L AALTONEN ◽  
...  

1997 ◽  
Vol 225 (2) ◽  
pp. 202-207 ◽  
Author(s):  
Miguel A. Rodríguez-Bigas ◽  
Hans F.A. Vasen ◽  
Jukka Pekka-Mecklin ◽  
Torben Myrhøj ◽  
Paul Rozen ◽  
...  

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