Treatment of equine squamous cell carcinoma of the conjunctiva using a strontium 90 applicator

2010 ◽  
Vol 15 (S2) ◽  
pp. 125-126 ◽  
Author(s):  
L. N. OWEN ◽  
K. C. BARNETT
2015 ◽  
Vol 45 (6) ◽  
pp. 1066-1072 ◽  
Author(s):  
Alexandre Lima de Andrade ◽  
Marco Antônio Rodrigues Fernandes ◽  
Silmara Sanae Sakamoto ◽  
Maria Cecília Rui Luvizotto

The purpose was to evaluate the effectiveness of beta-radiation with strontium-90 as single modality treatment of canine third eyelid squamous cell carcinoma (SCC). Nine dogs diagnosed with third eyelid SCC were treated with strontium-90. Radiation therapy was administered in four fractions of 100cGy per site every four days and at a depth of 0.2cm (Strontium-90 build' up) in each fraction. Radiation with beta therapy was well tolerated in all animals with no occurrence of radiation induced cataracts. In all cases, there were increased signs of conjunctival inflammation around the mass, which subsided with topical anti-inflammatory. Two dogs required surgical treatment for local tumor recurrence at 150 days and 352 days. In the remaining seven cases, disease free interval ranged from 1239 days to 2555 days. Beta therapy using 90Sr may be a valid alternative for the treatment of third eyelid SCC in dogs


2021 ◽  
pp. 1098612X2110381
Author(s):  
Onne-Marju Russak ◽  
Sara Verganti ◽  
Davide Berlato

Objectives Squamous cell carcinoma (SCC) is the most common eyelid tumour in cats. The main treatment is extensive surgery and the cosmetic outcome can be worrisome for some owners. Strontium 90 (ST-90) plesiotherapy is a therapeutic modality used for superficial tumours, including SCC. The aim of this study was to describe the use and response of feline eyelid SCC to ST-90 plesiotherapy either as single treatment or as adjuvant therapy following surgery. Methods A referral centre clinical database was searched for all cats diagnosed with SCC located on an eyelid. Cats treated with ST-90 plesiotherapy were included. The response to treatment was evaluated visually every 4–6 weeks until complete healing and based on response evaluation criteria in solid tumours (RECIST). Descriptive statistics of the survival were applied to the data collected. Results Eight cats treated between 2014 and 2017 met the inclusion criteria. The median age was 10.8 years. In six cases, ST-90 was used as the only treatment modality, while in two cats it was used as an adjuvant to surgery. Four cats received a single protocol and four a hypofractionated protocol. In the six cats in which ST-90 was used as the primary treatment, the response was 100%. Four cats died at a median time of 9 months (3–17 months) after ST-90 due to causes unrelated to SCC. Of the remaining four cats, three had no signs of recurrence at a median time of 34 months and one was lost to follow-up at 17 months with no signs of recurrence. Conclusions and relevance This small study showed that ST-90 can be used for treatment of eyelid SCC with good therapeutic and cosmetic outcomes.


2014 ◽  
Vol 18 (3) ◽  
pp. 254-260 ◽  
Author(s):  
Jessica C. Nevile ◽  
Simon D. Hurn ◽  
Andrew G. Turner ◽  
Christina McCowan

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