scholarly journals PR321: Does smoking and hyaluronic acid impact on the wound healing of free gingival graft and donor sites?

2018 ◽  
Vol 45 ◽  
pp. 228-228
2021 ◽  
Vol 2021 ◽  
pp. 1-10
Author(s):  
Ahmed Hassan ◽  
Enji Ahmed ◽  
Dalia Ghalwash ◽  
Azza Ezz Elarab

Aim. This study aimed to compare the effect of MEBO versus 0.2% hyaluronic acid gel (Gengigel®) applied to the palatal donor site on postoperative pain reduction and wound healing after free gingival graft harvesting. Methodology. Thirty-nine patients with different mucogingival defects were included in this study for harvesting a free gingival graft (FGG) for soft tissue augmentation. Patients were randomly assigned into three equal groups: group I (MEBO), group II (0.2% HA Gengigel®), and group III (control). Postoperative pain was recorded by using the Visual Analogue Scale (VAS). Analgesic consumption was recorded for 7 days postoperatively. Wound size was measured at baseline and on days 3, 7, 14, and 21. Postoperative healing of the palatal wound was assessed by the VAS score for color match on days 3, 7, 14, 21, and 42. Results. Results of this study showed significant postoperative pain reduction for the three groups; MEBO showed statistically significant less VAS score compared to the other two groups, while HA showed statistically significant less VAS score compared to the control group. Both MEBO and HA showed statistically significant less total analgesic consumption. No statistically significant difference was observed between groups for wound size. MEBO showed statistically significant higher VAS for color match. Conclusions. Both treatment modalities could reduce postoperative pain following harvesting of FGG and improve the palatal wound healing. However, MEBO showed better outcomes in terms of postoperative pain and color match.


Author(s):  
Shweta Agrawal ◽  
Pramod Kumar Koirala ◽  
Shalini Pradhan ◽  
Ranjita Shrestha Gorkhali

Free gingival graft is one of the technique used for root coverage so as to increase the inadequate keratinized tissue. The donor tissue is most frequently taken from the palate and generally the donor site is not covered or protected. Platelet rich fibrin is one of the good option for the wound coverage of donor site after free gingival graft so as to reduce the pain perception to patient and faster wound healing. The case report includes two cases with gingival recession, treated on the same day with free gingival graft with the use of platelet rich fibrin in the donor site in case 1 and without platelet rich fibrin in case 2 respectively which were compared for pain perception and wound healing postoperatively at 24 hours, 3 days, 5 days, 7 days and 14 days. There was less pain perception and discomfort in the donor site with the use of platelet rich fibrin and enhanced healing compared to donor site without platelet rich fibrin.


2015 ◽  
Vol 42 (6) ◽  
pp. 582-589 ◽  
Author(s):  
Huseyin Gencay Keceli ◽  
Bahadir Ugur Aylikci ◽  
Serhat Koseoglu ◽  
Anil Dolgun

2015 ◽  
Vol 86 (5) ◽  
pp. 674-681 ◽  
Author(s):  
Chen-Ying Wang ◽  
Sheng-Chueh Tsai ◽  
Min-Chen Yu ◽  
Yu-Fang Lin ◽  
Chih-Cheng Chen ◽  
...  

2020 ◽  
Vol 14 (01) ◽  
pp. 063-069 ◽  
Author(s):  
Filipa Sousa ◽  
Vanessa Machado ◽  
João Botelho ◽  
Luís Proença ◽  
José João Mendes ◽  
...  

Abstract Objective The aim of this study was to investigate the healing effect of advanced platelet-rich fibrin (A-PRF) clot membranes in palatal wounds, resulting from free gingival graft (FGG) harvesting, on the reepithelization rate and on the pain experience after surgery. Materials and Methods Twenty-five patients requiring FGG have participated in this prospective cohort study. After FGG harvesting, the test group (n = 14) received A-PRF clot membranes at the palatal wound and the control group (n = 11) received a gelatin sponge. Epithelialization rate of the palatal wound, wound healing area, correspondent percentage of reduction, and postsurgical pain experience were assessed at 2, 7, 14, 30, and 90 days. Results A-PRF group had higher palatal wound reduction than the control group, at 7, 14, and 30 days of follow-up. The highest difference between the groups was attained at 30 days (91.5% for A-PRF vs. 59.0% control group). At 14 days, a significant difference in the proportion of patients showing total epithelization was found: 64.3% for A-PRF versus 9.1% for the control group. At 90 days, both groups showed total recovery. The control group experienced higher pain level and discomfort until the 14th day, being notably higher on the second day. Conclusion The results suggest that A-PRF membranes haste the healing process, and promote greater reduction along the recovery period and less painful postoperative period.


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