scholarly journals Unique patterns of glycosylation in immunoglobulin subclass G4-related disease and primary sclerosing cholangitis

2018 ◽  
Vol 34 (10) ◽  
pp. 1878-1886 ◽  
Author(s):  
Emma L Culver ◽  
Fleur S van de Bovenkamp ◽  
Ninotska I L Derksen ◽  
Jana Koers ◽  
Tamsin Cargill ◽  
...  
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Related Disease ◽  
Immunoglobulin Subclass

scholarly journals Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis

2013 ◽  
Vol 45 (6) ◽  
pp. 670-675 ◽  
Author(s):  
Jimmy Z Liu ◽  
◽  
Johannes Roksund Hov ◽  
Trine Folseraas ◽  
Eva Ellinghaus ◽  
...  
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Related Disease

Human Leucocyte Antigen Associations in IGG4-Related Disease and Primary Sclerosing Cholangitis Stratified by IGG4 Levels, in a Multicenter UK Cohort

2016 ◽  
Vol 64 (2) ◽  
pp. S646
Author(s):  
E.L. Culver ◽  
J.M. Hurst ◽  
T. Cargill ◽  
D. Joshi ◽  
D. Nayar ◽  
...  
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Human Leucocyte Antigen ◽  
Related Disease ◽  
Igg4 Related Disease

scholarly journals Immunoglobulin G4+B-cell receptor clones distinguish immunoglobulin G 4-related disease from primary sclerosing cholangitis and biliary/pancreatic malignancies

Hepatology ◽  
2016 ◽  
Vol 64 (2) ◽  
pp. 501-507 ◽  
Author(s):  
Marieke E. Doorenspleet ◽  
Lowiek M. Hubers ◽  
Emma L. Culver ◽  
Lucas J. Maillette de Buy Wenniger ◽  
Paul L. Klarenbeek ◽  
...  
Keyword(s):  
B Cell ◽  
Primary Sclerosing Cholangitis ◽  
Immunoglobulin G ◽  
Sclerosing Cholangitis ◽  
Cell Receptor ◽  
B Cell Receptor ◽  
Immunoglobulin G4 ◽  
Related Disease

scholarly journals IgG4 Related Sclerosing Cholangitis

2014 ◽  
Vol 2014 ◽  
pp. 1-7 ◽  
Author(s):  
D. Joshi ◽  
G. J. M. Webster
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Autoimmune Pancreatitis ◽  
Sclerosing Cholangitis ◽  
Differential Diagnoses ◽  
Disease Entity ◽  
Future Directions ◽  
Related Disease ◽  
Management Algorithm ◽  
Igg4 Related Disease

IgG4 related disease (IgG4-RD) is a multisystemic disorder which has only recently been recognized. IgG4 related sclerosing cholangitis (IgG4-SC) is the biliary manifestation of the disease, often in association with autoimmune pancreatitis (AIP). In this review, we provide an overview of IgG4-RD, with a focus on the biliary manifestations. In particular, we describe the important differential diagnoses of IgG4-SC that need to be considered, namely, primary sclerosing cholangitis (PSC) and cholangiocarcinoma, and provide a management algorithm. Finally, we highlight future directions and unanswered questions which will provide new insights into this exciting and evolving disease entity.

New autoantibodies in primary sclerosing cholangitis: reactivity with distinct immunodominant epitopes of sulfite oxidase

2010 ◽  
Vol 48 (01) ◽  
Author(s):  
BE Preuß ◽  
C Berg ◽  
F Altenberend ◽  
M Gregor ◽  
S Stevanovic ◽  
...  
Keyword(s):  
Primary Sclerosing Cholangitis ◽  
Sclerosing Cholangitis ◽  
Sulfite Oxidase ◽  
Immunodominant Epitopes
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