Evolutionary patterns of major urinary protein scent signals in house mice and relatives

2019 ◽  
Vol 28 (15) ◽  
pp. 3587-3601 ◽  
Author(s):  
Michael J. Sheehan ◽  
Polly Campbell ◽  
Caitlin H. Miller
Keyword(s):  
Urinary Protein ◽  
House Mice ◽  
Major Urinary Protein ◽  
Evolutionary Patterns

Major Urinary Protein Complex of Normal Mice: Origin

Science ◽  
1965 ◽  
Vol 149 (3687) ◽  
pp. 981-982 ◽  
Author(s):  
J. S. Finlayson ◽  
R. Asofsky ◽  
M. Potter ◽  
C. C. Runner
Keyword(s):  
Protein Complex ◽  
Urinary Protein ◽  
Major Urinary Protein

A 45-kb DNA domain with two divergently orientated genes is the unit of organisation of the murine major urinary protein genes.

1984 ◽  
Vol 3 (9) ◽  
pp. 2055-2064 ◽  
Author(s):  
A.J. Clark ◽  
J. Hickman ◽  
J. Bishop
Keyword(s):  
Urinary Protein ◽  
Major Urinary Protein

scholarly journals PRDM9 Diversity at Fine Geographical Scale Reveals Contrasting Evolutionary Patterns and Functional Constraints in Natural Populations of House Mice

2019 ◽  
Vol 36 (8) ◽  
pp. 1686-1700 ◽  
Author(s):  
Covadonga Vara ◽  
Laia Capilla ◽  
Luca Ferretti ◽  
Alice Ledda ◽  
Rosa A Sánchez-Guillén ◽  
...  
Keyword(s):  
Reproductive Isolation ◽  
Evolutionary Biology ◽  
Evolutionary Dynamics ◽  
Rapid Evolution ◽  
Natural Populations ◽  
Global Scale ◽  
House Mice ◽  
Functional Constraints ◽  
Evolutionary Patterns ◽  
Data Set

Abstract One of the major challenges in evolutionary biology is the identification of the genetic basis of postzygotic reproductive isolation. Given its pivotal role in this process, here we explore the drivers that may account for the evolutionary dynamics of the PRDM9 gene between continental and island systems of chromosomal variation in house mice. Using a data set of nearly 400 wild-caught mice of Robertsonian systems, we identify the extent of PRDM9 diversity in natural house mouse populations, determine the phylogeography of PRDM9 at a local and global scale based on a new measure of pairwise genetic divergence, and analyze selective constraints. We find 57 newly described PRDM9 variants, this diversity being especially high on Madeira Island, a result that is contrary to the expectations of reduced variation for island populations. Our analysis suggest that the PRDM9 allelic variability observed in Madeira mice might be influenced by the presence of distinct chromosomal fusions resulting from a complex pattern of introgression or multiple colonization events onto the island. Importantly, we detect a significant reduction in the proportion of PRDM9 heterozygotes in Robertsonian mice, which showed a high degree of similarity in the amino acids responsible for protein–DNA binding. Our results suggest that despite the rapid evolution of PRDM9 and the variability detected in natural populations, functional constraints could facilitate the accumulation of allelic combinations that maintain recombination hotspot symmetry. We anticipate that our study will provide the basis for examining the role of different PRDM9 genetic backgrounds in reproductive isolation in natural populations.

Starch-Gel Electrophoresis of Murine Major Urinary Protein

1970 ◽  
Vol 135 (1) ◽  
pp. 81-83 ◽  
Author(s):  
H. A. Hoffman
Keyword(s):  
Gel Electrophoresis ◽  
Urinary Protein ◽  
Starch Gel Electrophoresis ◽  
Major Urinary Protein ◽  
Starch Gel

Backbone Motions of Free and Pheromone-Bound Major Urinary Protein I Studied by Molecular Dynamics Simulation

2007 ◽  
Vol 111 (20) ◽  
pp. 5731-5739 ◽  
Author(s):  
Pavel Macek ◽  
Petr Novák ◽  
Lukáš Žídek ◽  
Vladimír Sklenář
Keyword(s):  
Molecular Dynamics ◽  
Molecular Dynamics Simulation ◽  
Urinary Protein ◽  
Dynamics Simulation ◽  
Major Urinary Protein

Extraction, characterization, and binding analysis of two pheromonally active ligands associated with major urinary protein of house mouse (Mus musculus)

1993 ◽  
Vol 19 (7) ◽  
pp. 1405-1416 ◽  
Author(s):  
Duncan H. L. Robertson ◽  
Robert J. Beynon ◽  
Richard P. Evershed
Keyword(s):  
House Mouse ◽  
Mus Musculus ◽  
Urinary Protein ◽  
Major Urinary Protein ◽  
Binding Analysis

Variation between mouse major urinary protein genes isolated from a single inbred line

Gene ◽  
1982 ◽  
Vol 18 (3) ◽  
pp. 221-230 ◽  
Author(s):  
A.John Clark ◽  
Patricia M. Clissold ◽  
John O. Bishop
Keyword(s):  
Inbred Line ◽  
Urinary Protein ◽  
Major Urinary Protein

scholarly journals Molecular complexity of the major urinary protein system of the Norway rat, Rattus norvegicus

2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Guadalupe Gómez-Baena ◽  
Stuart D. Armstrong ◽  
Josiah O. Halstead ◽  
Mark Prescott ◽  
Sarah A. Roberts ◽  
...  
Keyword(s):  
Rattus Norvegicus ◽  
Urinary Protein ◽  
Major Urinary Protein ◽  
Norway Rat ◽  
Protein System ◽  
Molecular Complexity
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