scholarly journals Nitrate‐inducible MdBT2 acts as a restriction factor to limit apple necrotic mosaic virus genome replication in Malus domestica

2021 ◽  
Author(s):  
Zhenlu Zhang ◽  
Yin‐Huan Xie ◽  
Ping Sun ◽  
Fu‐Jun Zhang ◽  
Peng‐Fei Zheng ◽  
...  
Keyword(s):  
Mosaic Virus ◽  
Malus Domestica ◽  
Virus Genome ◽  
Restriction Factor ◽  
Genome Replication

scholarly journals Further Evidence that Viroplasms Are the Site of Cauliflower Mosaic Virus Genome Replication by Reverse Transcription during Viral Infection

1989 ◽  
Vol 70 (12) ◽  
pp. 3439-3449 ◽  
Author(s):  
L. Mazzolini ◽  
P. Dabos ◽  
S. Constantin ◽  
P. Yot
Keyword(s):  
Viral Infection ◽  
Mosaic Virus ◽  
Reverse Transcription ◽  
Virus Genome ◽  
Cauliflower Mosaic Virus ◽  
Genome Replication

First Detection of Tobacco Mosaic Virus in Tobacco Fields in Northern Lebanon

2020 ◽  
Vol 20 ◽  
Author(s):  
Rami Obeid ◽  
Elias Wehbe ◽  
Mohamad Rima ◽  
Mohammad Kabara ◽  
Romeo Al Bersaoui ◽  
...  
Keyword(s):  
Tobacco Mosaic Virus ◽  
Mosaic Virus ◽  
Viral Genome ◽  
Virus Genome ◽  
Enzyme Linked Immunosorbent Assay ◽  
Virus Family ◽  
Crop Fields ◽  
Wide Range ◽  
Almost All ◽  
Das Elisa

Background: Tobacco mosaic virus (TMV) is the most known virus in the plant mosaic virus family and is able to infect a wide range of crops, in particularly tobacco, causing a production loss. Objectives: Herein, and for the first time in Lebanon, we investigated the presence of TMV infection in crops by analyzing 88 samples of tobacco, tomato, cucumber and pepper collected from different regions in North Lebanon. Methods: Double-antibody sandwich enzyme-linked immunosorbent assay (DAS-ELISA), revealed a potential TMV infection of four tobacco samples out of 88 crops samples collected. However, no tomato, cucumber and pepper samples were infected. The TMV+ tobacco samples were then extensively analyzed by RT-PCR to detect viral RNA using different primers covering all the viral genome. Results and Discussion: PCR results confirmed those of DAS-ELISA showing TMV infection of four tobacco samples collected from three crop fields of North Lebanon. In only one of four TMV+ samples, we were able to amplify almost all the regions of viral genome, suggesting possible mutations in the virus genome or an infection with a new, not yet identified, TMV strain. Conclusion: Our study is the first in Lebanon revealing TMV infection in crop fields, and highlighting the danger that may affect the future of agriculture.

Molecular characterization of the Indian strain of Apple mosaic virus isolated from apple (Malus domestica)

2009 ◽  
Vol 37 (4) ◽  
pp. 375-379 ◽  
Author(s):  
Tombisana Thokchom ◽  
Tanuja Rana ◽  
Vipin Hallan ◽  
Raja Ram ◽  
Aijaz A. Zaidi
Keyword(s):  
Mosaic Virus ◽  
Molecular Characterization ◽  
Malus Domestica ◽  
Indian Strain

scholarly journals MicroRNA-135a Modulates Hepatitis C Virus Genome Replication through Downregulation of Host Antiviral Factors

2018 ◽  
Vol 34 (2) ◽  
pp. 197-210 ◽  
Author(s):  
Catherine Sodroski ◽  
Brianna Lowey ◽  
Laura Hertz ◽  
T. Jake Liang ◽  
Qisheng Li
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Virus Genome ◽  
Genome Replication

Pea Enation Mosaic Virus Genome RNA Contains No Polyadenylate Sequences and Cannot Be Aminoacylated

Intervirology ◽  
1978 ◽  
Vol 9 (4) ◽  
pp. 226-230 ◽  
Author(s):  
Thomas L. German ◽  
Gustaaf A. De Zoeten ◽  
Timothy C. Hall
Keyword(s):  
Mosaic Virus ◽  
Virus Genome ◽  
Pea Enation Mosaic Virus

Expression of the Cauliflower Mosaic Virus Genome in Turnips (Brassica Rapa)

1980 ◽  
pp. 529-536 ◽  
Author(s):  
S. H. Howell ◽  
J. T. Odell ◽  
K. R. Dudley
Keyword(s):  
Mosaic Virus ◽  
Brassica Rapa ◽  
Virus Genome ◽  
Cauliflower Mosaic Virus

scholarly journals Involvement of Creatine Kinase B in Hepatitis C Virus Genome Replication through Interaction with the Viral NS4A Protein

2009 ◽  
Vol 83 (10) ◽  
pp. 5137-5147 ◽  
Author(s):  
Hiromichi Hara ◽  
Hideki Aizaki ◽  
Mami Matsuda ◽  
Fumiko Shinkai-Ouchi ◽  
Yasushi Inoue ◽  
...  
Keyword(s):  
Creatine Kinase ◽  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Viral Genome ◽  
Proteome Analysis ◽  
Virus Genome ◽  
Genome Replication ◽  
Creatine Kinase B ◽  
Efficient Replication

ABSTRACT Persistent infection with hepatitis C virus (HCV) is a major cause of chronic liver diseases. The aim of this study was to identify host cell factor(s) participating in the HCV replication complex (RC) and to clarify the regulatory mechanisms of viral genome replication dependent on the host-derived factor(s) identified. By comparative proteome analysis of RC-rich membrane fractions and subsequent gene silencing mediated by RNA interference, we identified several candidates for RC components involved in HCV replication. We found that one of these candidates, creatine kinase B (CKB), a key ATP-generating enzyme that regulates ATP in subcellular compartments of nonmuscle cells, is important for efficient replication of the HCV genome and propagation of infectious virus. CKB interacts with HCV NS4A protein and forms a complex with NS3-4A, which possesses multiple enzyme activities. CKB upregulates both NS3-4A-mediated unwinding of RNA and DNA in vitro and replicase activity in permeabilized HCV replicating cells. Our results support a model in which recruitment of CKB to the HCV RC compartment, which has high and fluctuating energy demands, through its interaction with NS4A is important for efficient replication of the viral genome. The CKB-NS4A association is a potential target for the development of a new type of antiviral therapeutic strategy.

scholarly journals Evaluation of Canonical siRNA and Dicer Substrate RNA for Inhibition of Hepatitis C Virus Genome Replication – A Comparative Study

PLoS ONE ◽  
2015 ◽  
Vol 10 (2) ◽  
pp. e0117742 ◽  
Author(s):  
Bruno Carneiro ◽  
Ana Cláudia Silva Braga ◽  
Mariana Nogueira Batista ◽  
Mark Harris ◽  
Paula Rahal
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Comparative Study ◽  
Virus Genome ◽  
Genome Replication
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