Stability and Effect of Parkinsonian State on Deep Brain Stimulation Cortical Evoked Potentials

2021 ◽  
Author(s):  
Brett A. Campbell ◽  
Hanbin Cho ◽  
Riley M. Faulhammer ◽  
Olivia Hogue ◽  
Jenny Peih‐Chir Tsai ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Brain Stimulation ◽  
Cortical Evoked Potentials ◽  
Deep Brain

Cortical-evoked potentials from deep brain stimulation

2020 ◽  
pp. 143-155
Author(s):  
Kenneth B Baker ◽  
Erwin B Montgomery
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Brain Stimulation ◽  
Cortical Evoked Potentials ◽  
Deep Brain

Short latency cortical evoked potentials elicited by subthalamic nucleus deep brain stimulation: Commentary and results from paired pulse studies

2020 ◽  
Vol 131 (2) ◽  
pp. 465-467 ◽  
Author(s):  
Mohammad Z. Awad ◽  
Zachary T. Irwin ◽  
Ryan J. Vaden ◽  
Barton L. Guthrie ◽  
Harrison C. Walker
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Subthalamic Nucleus ◽  
Brain Stimulation ◽  
Short Latency ◽  
Paired Pulse ◽  
Cortical Evoked Potentials ◽  
Deep Brain

Deep brain stimulation reduces evoked potentials with a dual time course in freely moving rats: Potential neurophysiological basis for intermittent as an alternative to continuous stimulation

Epilepsia ◽  
2020 ◽  
Vol 61 (5) ◽  
pp. 903-913
Author(s):  
Mathieu Sprengers ◽  
Robrecht Raedt ◽  
Lars Emil Larsen ◽  
Jean Delbeke ◽  
Wytse Jan Wadman ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Brain Stimulation ◽  
Time Course ◽  
Continuous Stimulation ◽  
Freely Moving Rats ◽  
Freely Moving ◽  
Neurophysiological Basis ◽  
Deep Brain

scholarly journals Intraoperative Characterization of Subthalamic Nucleus-to-Cortex Evoked Potentials in Parkinson’s Disease Deep Brain Stimulation

2021 ◽  
Vol 15 ◽  
Author(s):  
Lila H. Levinson ◽  
David J. Caldwell ◽  
Jeneva A. Cronin ◽  
Brady Houston ◽  
Steve I. Perlmutter ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Subthalamic Nucleus ◽  
Brain Stimulation ◽  
High Frequency ◽  
Therapeutic Effects ◽  
Stn Dbs ◽  
Deep Brain

Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a clinically effective tool for treating medically refractory Parkinson’s disease (PD), but its neural mechanisms remain debated. Previous work has demonstrated that STN DBS results in evoked potentials (EPs) in the primary motor cortex (M1), suggesting that modulation of cortical physiology may be involved in its therapeutic effects. Due to technical challenges presented by high-amplitude DBS artifacts, these EPs are often measured in response to low-frequency stimulation, which is generally ineffective at PD symptom management. This study aims to characterize STN-to-cortex EPs seen during clinically relevant high-frequency STN DBS for PD. Intraoperatively, we applied STN DBS to 6 PD patients while recording electrocorticography (ECoG) from an electrode strip over the ipsilateral central sulcus. Using recently published techniques, we removed large stimulation artifacts to enable quantification of STN-to-cortex EPs. Two cortical EPs were observed – one synchronized with DBS onset and persisting during ongoing stimulation, and one immediately following DBS offset, here termed the “start” and the “end” EPs respectively. The start EP is, to our knowledge, the first long-latency cortical EP reported during ongoing high-frequency DBS. The start and end EPs differ in magnitude (p < 0.05) and latency (p < 0.001), and the end, but not the start, EP magnitude has a significant relationship (p < 0.001, adjusted for random effects of subject) to ongoing high gamma (80–150 Hz) power during the EP. These contrasts may suggest mechanistic or circuit differences in EP production during the two time periods. This represents a potential framework for relating DBS clinical efficacy to the effects of a variety of stimulation parameters on EPs.

Deep Brain Stimulation Evoked Potentials May Relate to Clinical Benefit in Childhood Dystonia

2014 ◽  
Vol 7 (5) ◽  
pp. 718-726 ◽  
Author(s):  
Nasir H. Bhanpuri ◽  
Matteo Bertucco ◽  
Diana Ferman ◽  
Scott J. Young ◽  
Mark A. Liker ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Brain Stimulation ◽  
Clinical Benefit ◽  
Deep Brain

scholarly journals Evoked potentials reveal neural circuits engaged by human deep brain stimulation

2020 ◽  
Vol 13 (6) ◽  
pp. 1706-1718
Author(s):  
Stephen L. Schmidt ◽  
David T. Brocker ◽  
Brandon D. Swan ◽  
Dennis A. Turner ◽  
Warren M. Grill
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Brain Stimulation ◽  
Neural Circuits ◽  
Deep Brain

Platform Session – Evoked potentials & NIOM: Somatosensory evoked potentials and central motor conduction times help predict outcomes from deep brain stimulation (DBS) in children with dystonia

2018 ◽  
Vol 129 ◽  
pp. e229
Author(s):  
Verity M. McClelland ◽  
Doreen Fialho ◽  
Denise Flexney-Briscoe ◽  
Graham Holder ◽  
Markus Elze ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Brain Stimulation ◽  
Somatosensory Evoked Potentials ◽  
Deep Brain

scholarly journals Effects of ketamine and propofol on motor evoked potentials elicited by intracranial microstimulation during deep brain stimulation

2014 ◽  
Vol 8 ◽  
Author(s):  
Havan Furmaga ◽  
Hyun-Joo Park ◽  
Jessica Cooperrider ◽  
Kenneth B. Baker ◽  
Matthew Johnson ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Evoked Potentials ◽  
Brain Stimulation ◽  
Motor Evoked Potentials ◽  
Deep Brain
Sign in / Sign up

Export Citation Format

Share Document