Background: There is no consensus regarding the optimal anesthetic
approach to rigid bronchoscopy in children suffering from
tracheobronchial FBA. We performed this meta-analysis to assess the
efficacy and safety of the different anesthesia agents and ventilation
modes for tracheobronchial foreign body removal via rigid bronchoscopy
in young children. Methods: A systematic search of three major databases
for all relevant articles. A meta-analysis was performed to analyze the
data. Results: Four trials for evaluating different anesthetics and six
trials for evaluating two kinds of ventilation modes were found.
Compared with the sevoflurane-based volatile anesthesia group , the rate
of perioperative complications included hypoxemia (OR, 2.07; 95% CI,
1.38–3.11; P=0.0004; I2 = 0%), apnea (OR, 2.74; 95% CI, 1.11–6.78; P
= 0.03; I2 = 60%), laryngospasm (OR, 2.89; 95% CI, 1.67–4.98;
P=0.0001; I2 = 0%), cough/bucking (OR, 2.93; 95% CI, 1.86–4.63;
P<0.00001; I2 = 0%), and body movement (OR, 3.51; 95% CI,
2.03–6.09; P<0.00001; I2 = 0%) were significantly increased
in the propofol-based total intravenous anesthesia and the duration of
operation were longer in the Group Prop. Compared with the control
ventilation group , the incidences of laryngospasm (OR, 0.16; 95% CI,
0.05–0.56; P=0.004; I2 = 54%), apnea (OR, 0.21; 95% CI, 0.09–0.50;
P=0.0004; I2 = 0%), and cough/bucking (OR, 0.03; 95% CI, 0.01–0.10;
P<0.00001; I2 = 41%) increased in the spontaneous ventilation
group and the duration of operationand emergence from anesthesia
significantly prolonged in the Group SV. Conclusions: Our meta-analysis
suggests that sevoflurane-based volatile anesthesia was superior to
propofol-based total intravenous anesthesia for the management of
foreign body aspiration in children. There is still no strong evidence
indicated that one ventilation technique was superio
Incidence of Postoperative Cognitive Dysfunction Following Inhalational Vs. Total Intravenous General Anesthesia: A Systematic Review and Meta-Analysis.
