ophthalmic surgery
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2021 ◽  
Vol 49 (6) ◽  
pp. 439-444
Author(s):  
Andi Ade Wijaya Ramlan ◽  
◽  
Irwan Mahri ◽  
Riyadh Firdaus ◽  
Ardhie Sugiarto ◽  
...  

Thyroid ◽  
2021 ◽  
Author(s):  
Timothy Woo ◽  
Chunhei Li ◽  
Sashiananthan Ganesananthan ◽  
Rathie Rajendram ◽  
Jimmy Uddin ◽  
...  

2021 ◽  
Vol 75 ◽  
pp. 110483
Author(s):  
Aihuan Chen ◽  
Hengwei Sheng ◽  
Zhubin Xie ◽  
Weihua Shen ◽  
Qianru Chen ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Dong Ju Kim ◽  
Mi-Young Jung ◽  
Joo-Hee Park ◽  
Ha-Jin Pak ◽  
Martha Kim ◽  
...  

AbstractIntraocular antibiotic delivery is an important technique to prevent bacterial infection after ophthalmic surgery, such as cataract surgery. Conventional drug delivery methods, such as antibiotic eye drops, have limitations for intraocular drug delivery due to the intrinsic barrier effect of the cornea. Therefore, frequent instillation of antibiotic eyedrops is necessary to reach a sufficient bactericidal concentration inside the eye. In this study, an intraocular implant, MXF-HA, that combines hyaluronic acid (HA) and moxifloxacin (MXF) was developed to increase the efficiency of intraocular drug delivery after surgery. MXF-HA is manufactured as a thin, transparent, yellow-tinted membrane. When inserted into the eye in a dry state, MXF-HA is naturally hydrated and settles in the eye, and the MXF contained therein is delivered by hydrolysis of the polymer over time. It was confirmed through in vivo experiments that MXF delivery was maintained in the anterior chamber of the eye at a concentration sufficient to inhibit Pseudomonas aeruginosa and Staphylococcus aureus for more than 5 days after implantation. These results suggest that MXF-HA can be utilized as a potential drug delivery method for the prevention and treatment of bacterial infections after ophthalmic surgery.


Pain medicine ◽  
2021 ◽  
Vol 6 (3) ◽  
pp. 36-41
Author(s):  
Maxim Khodakovsky

Background. The aim of the study is to evaluate the quality and safety of the sedative effect of anesthesia in ambulant ophthalmic surgery by using continuous intravenous infu­sion of Dexmedetomidine. Materials and Methods. Patients were randomized into groups by age (people from 65 to 75 years old, old age 76 years, middle age, young people, children), by gender (men, women). The physical status of patients was assessed using the ASA scale and the dynamics of vegetatic activity by the Kerdo index. Sedation was assessed using the Richmond Sedation Scale RASS.Results. It was found that the difference in the frequency of adverse effects of the appointment of Dexmedetomidine clearly confirms the need to adjust the dose of Dexmede­tomidine, depending on the state of the autonomic nervous system. The use of Dexmedetomidine according to the rec­ommendations made it possible to achieve a safe level of sedation and eliminate side effects in ambulant ophthalmic surgery.Conclusions: Parenteral continuous infusion of Dexmedetomidine pro­vides an effective level of sedation for ambulant ophthalmic surgery and maintaining patient­surgeon contact. Safety is confirmed by a low level of critical incidents, no respiratory depression at the target sedation level. The patency of the upper airways was better compared to previous experience with propofol.


2021 ◽  
pp. 112067212110590
Author(s):  
Annalisa De Nucci ◽  
Antonio Scialdone ◽  
Gabriele Lando ◽  
Gaspare Monaco ◽  
Viviana Cacioppo ◽  
...  

Purpose To assess the effectiveness and safety of intravenous (IV) dexmedetomidine for sedation in ophthalmic surgery. Methods Prospective, observational, uncontrolled, single-center study. Patients were sedated with a continuous dexmedetomidine IV infusion started 15 min before regional anesthesia administration and maintained up to the end of surgery. Effectiveness of dexmedetomidine was assessed by the Modified Observer's Assessment of Alertness and Sedation (MOAA/S) targeted at 5. Safety was assessed by the incidence of patients’ movements/snoring and by the incidence of respiratory and haemodynamic complications. An eleven-point numerical rating scale (NRS) was used to assess the level of satisfaction of both the surgeon and the patient. Results 123 patients (73 males, mean age: 63 ± 13) were included; 81 (81/123; 65.8%) patients reached the requested MOAA/S score of 5. Any intraoperative movement – mostly voluntary – occurred in 34 (34/123; 27.6%) cases with no need for a switch to general anaesthesia; no ocular complications related to the intraoperative movements occurred. Intraoperative snoring occurred in 30 (30/123; 24.4%) patients and it did not affect the surgical manoeuvres. Respiratory drive depression requiring manual or mechanical ventilation never occurred. Bradycardia occurred in 14 (14/123; 11.3%), cases but only 4 (4/123; 3.2%) patients required atropine administration, which was always effective. Intraoperative analgesia was consistently obtained and both the surgeons and the patients reported a high NRS satisfaction score. Conclusion Dexmedetomidine provided adequate sedation in patients undergoing ocular surgery under local anaesthesia and showed a good effectiveness and safety profile. Upper airway obstruction, apnoea and snoring can occur.


2021 ◽  
pp. 799-816
Author(s):  
Peter B Williamson

This chapter discusses the anaesthetic management of ophthalmic surgery. It begins with a description of general principles, including anatomy and physiology of the globe and orbit, preoperative considerations of ophthalmology patients, and a discussion of different ocular block techniques. Surgical procedures covered include cataract extraction and intra-ocular lens (IOL) implantation; strabismus surgery; vitreo-retinal surgery; dacrocystorhinostomy (DCR), and repair of penetrating eye injuries.


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