The infectious cDNA clone of commercial HP‐PRRS JXA1‐R‐attenuated vaccine can be a potential effective live vaccine vector

Author(s):  
Nanhua Chen ◽  
Shubin Li ◽  
Xinshuai Li ◽  
Mengxue Ye ◽  
Yanzhao Xiao ◽  
...  
Virology ◽  
1986 ◽  
Vol 151 (1) ◽  
pp. 21-30 ◽  
Author(s):  
Michinori Kohara ◽  
Shinobu Abe ◽  
Shusuke Kuge ◽  
Bert L. Semler ◽  
Toshihiko Komatsu ◽  
...  

2000 ◽  
Vol 31 (1) ◽  
pp. 59-60
Author(s):  
P. J.G.M. Steverink ◽  
J. M.A. Pol ◽  
J.N.A. Bos-de Ruijter ◽  
J. J.M. Meulenberg

Author(s):  
Hongqing Zhu ◽  
Yin Liu ◽  
Yingyun Cai ◽  
Dongdong Yu ◽  
Yinghui Pu ◽  
...  

Author(s):  
J. J. M. Meulenberg ◽  
J. N. A. Bos-de Ruijter ◽  
G. Wensvoort ◽  
R. J. M. Moormann

2005 ◽  
Vol 21 (4) ◽  
pp. 361-368 ◽  
Author(s):  
Ju-Yeon Yoon ◽  
Jin-Sung Hong ◽  
Min-Jea Kim ◽  
Ju-Hee Ha ◽  
Gug-Seon Choi ◽  
...  

2002 ◽  
Vol 76 (16) ◽  
pp. 8494-8503 ◽  
Author(s):  
Christiane Meyer ◽  
Martina von Freyburg ◽  
Knut Elbers ◽  
Gregor Meyers

ABSTRACT Cloned cDNA derived from the genome of the virulent type 2 bovine viral diarrhea virus (BVDV) strain NY'93/C was sequenced and served for establishment of the infectious cDNA clone pKANE40A. Virus recovered from pKANE40A exhibited growth characteristics similar to those of wild-type BVDV NY'93/C and proved to be clinically indistinguishable from the wild-type virus in animal experiments. A virus mutant in which the RNase residing in the viral glycoprotein Erns was inactivated, revealed an attenuated phenotype. The plasmid pKANE40A represents the first infectious cDNA clone established for a type 2 BVDV and offers a variety of new approaches to analyze the mechanisms of BVDV-induced disease in cattle.


2009 ◽  
Vol 142 (1-2) ◽  
pp. 204-207 ◽  
Author(s):  
Wu-yang Zhu ◽  
Shi-hong Fu ◽  
Jing-lin Wang ◽  
Ying He ◽  
Qing Tang ◽  
...  

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