Cutaneous presentation of progressive disseminated histoplasmosis nine years after renal transplantation

2013 ◽  
Vol 15 (2) ◽  
pp. E64-E69 ◽  
Author(s):  
V.M. Rosado-Odom ◽  
J. Daoud ◽  
R. Johnson ◽  
S.D. Allen ◽  
S.R. Lockhart ◽  
...  
Keyword(s):  
Renal Transplantation ◽  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

Treatment Of Disseminated Histoplasmosis With Ethyl Vanillate

PEDIATRICS ◽  
1951 ◽  
Vol 7 (1) ◽  
pp. 7-18
Author(s):  
AMOS CHRISTIE ◽  
JAMES G. MIDDLETON ◽  
J. CYRIL PETERSON ◽  
DAVID L. MCVICKAR
Keyword(s):  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

Some of the physical and pharmacologic properties of ethyl vanillate, a new fungistatic or fungicidal agent, have been briefly stated. The records of 12 patients with progressive disseminated histoplasmosis treated with ethyl vanillate have been reviewed. Five of these patients are alive and apparently well following treatment, an experience not previously encountered or reported in the literature. The use of the drug in the treatment of histoplasmosis has been outlined and the toxic manifestations of overdosage have been described.

scholarly journals Bats, Fever and Adenopathy – What Is the Link?

2013 ◽  
Vol 24 (1) ◽  
pp. 35-37 ◽  
Author(s):  
Joshua J Manolakos ◽  
Mohan Cooray ◽  
Ameen Patel ◽  
Shariq Haider
Keyword(s):  
Costa Rica ◽  
Environmental Exposure ◽  
Salvage Therapy ◽  
Histoplasma Capsulatum ◽  
Treatment Options ◽  
Diagnostic Approach ◽  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

A case of travel-related, subacute, progressive disseminated histoplasmosis in a nonimmunocompromised individual is described. The present case highlights the environmental exposure toHistoplasma capsulatumin Costa Rica, the diagnostic approach and treatment options, as well as new alternatives for salvage therapy for histoplasmosis infection.

scholarly journals Hemophagocytic Lymphohistiocytosis and Progressive Disseminated Histoplasmosis

2016 ◽  
Vol 22 (6) ◽  
pp. 1119-1121 ◽  
Author(s):  
Kenice Ferguson-Paul ◽  
Spencer Mangum ◽  
Ashley Porter ◽  
Vasiliki Leventaki ◽  
Patrick Campbell ◽  
...  
Keyword(s):  
Hemophagocytic Lymphohistiocytosis ◽  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

scholarly journals Typical Facial Lesions: A Window of Suspicion for Progressive Disseminated Histoplasmosis—A Case of Asian Prototype

2016 ◽  
Vol 2016 ◽  
pp. 1-5
Author(s):  
Prasan K. Panda ◽  
Siddharth Jain ◽  
Rita Sood ◽  
Rajni Yadav ◽  
Naval K. Vikram
Keyword(s):  
Histoplasma Capsulatum ◽  
Bone Marrow Aspiration ◽  
Febrile Illness ◽  
Immunocompetent Patient ◽  
Dimorphic Fungus ◽  
Recent Onset ◽  
Disseminated Histoplasmosis ◽  
The Face ◽  
History Of ◽  
Progressive Disseminated Histoplasmosis

Histoplasmosis is caused by a dimorphic fungusHistoplasma capsulatumin endemic areas, mainly America, Africa, and Asia. In India, it is being reported from most states; however, it is endemic along the Ganges belt. We report a case of an apparently immunocompetent male who presented with 3-month history of fever, cough, and weight loss with recent onset odynophagia and had hepatosplenomegaly and mucocutaneous lesions over the face. The differential diagnosis of leishmaniasis, tuberculosis, leprosy, fungal infection, lymphoproliferative malignancy, and other granulomatous disorders was considered, but he succumbed to his illness. Antemortem skin biopsy and bone marrow aspiration along with postmortem liver, lung, and spleen biopsy showed disseminated histoplasmosis. This case highlights the need for an early suspicion of progressive disseminated histoplasmosis in the presence of classical mucocutaneous lesions even in an immunocompetent patient suffering from a febrile illness. Cure rate approaches almost 100% with early treatment, whereas it is universally fatal if left untreated.

scholarly journals A rare presentation of progressive disseminated histoplasmosis in an immunocompetent patient from a non-endemic region

2013 ◽  
Vol 2 ◽  
pp. 103-107 ◽  
Author(s):  
M.V.S. Subbalaxmi ◽  
P. Umabala ◽  
Roshni Paul ◽  
Naval Chandra ◽  
Y.S. Raju ◽  
...  
Keyword(s):  
Immunocompetent Patient ◽  
Endemic Region ◽  
Rare Presentation ◽  
Disseminated Histoplasmosis ◽  
Progressive Disseminated Histoplasmosis

scholarly journals Detection of Histoplasma capsulatum Antigen in Panamanian Patients with Disseminated Histoplasmosis and AIDS

2008 ◽  
Vol 15 (4) ◽  
pp. 681-683 ◽  
Author(s):  
Maria Eugenia Gutierrez ◽  
Alfredo Canton ◽  
Patricia Connolly ◽  
Robert Zarnowski ◽  
L. Joseph Wheat
Keyword(s):  
United States ◽  
Latin American ◽  
Histoplasma Capsulatum ◽  
Severe Disease ◽  
Nuclear Gene ◽  
The United States ◽  
Antigen Detection ◽  
Disseminated Histoplasmosis ◽  
Antigen Assay ◽  
Progressive Disseminated Histoplasmosis

ABSTRACT Histoplasmosis is a common endemic mycosis in the Americas, often causing severe disease in patients with AIDS. Antigen detection has become an important method for rapid diagnosis of histoplasmosis in the United States but not in Central or South America. Isolates from patients in the United States are predominantly found to be class 2 isolates when typed using the nuclear gene YPS3, while isolates from Latin America are predominantly typed as class 5 or class 6. Whether infection with these Latin American genotypes produces positive results in the Histoplasma antigen assay has not been reported. In this study, we have compared the sensitivity of antigen detection for AIDS patients from Panama who had progressive disseminated histoplasmosis to that for those in the United States. Antigenuria was detected in the MVista Histoplasma antigen enzyme immunoassay (EIA) in 95.2% of Panamanian cases versus 100% of U.S. cases. Antigenemia was detected in 94.7% of the Panamanian cases versus 92% of the U.S. cases. Two clinical isolates from Panama were typed using YPS3 and were found to be restriction fragment length polymorphism class 6. We conclude that the MVista Histoplasma antigen EIA is a sensitive method for diagnosis of histoplasmosis in Panama.

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