scholarly journals Arabidopsis CHROMOSOME TRANSMISSION FIDELITY 7 ( AtCTF7 / ECO1 ) is required for DNA repair, mitosis and meiosis

2013 ◽  
Vol 75 (6) ◽  
pp. 927-940 ◽  
Author(s):  
Pablo Bolaños‐Villegas ◽  
Xiaohui Yang ◽  
Huei‐Jing Wang ◽  
Chien‐Ta Juan ◽  
Min‐Hsiang Chuang ◽  
...  
Keyword(s):  
Dna Repair ◽  
Chromosome Transmission ◽  
Arabidopsis Chromosome ◽  
Mitosis And Meiosis

scholarly journals Smc5p Promotes Faithful Chromosome Transmission and DNA Repair inSaccharomyces cerevisiae

Genetics ◽  
2006 ◽  
Vol 172 (4) ◽  
pp. 2185-2200 ◽  
Author(s):  
Gregory J. Cost ◽  
Nicholas R. Cozzarelli
Keyword(s):  
Dna Repair ◽  
Chromosome Transmission

scholarly journals The ctf13-30/CTF13 Genomic Haploinsufficiency Modifier Screen Identifies the Yeast Chromatin Remodeling Complex RSC, Which Is Required for the Establishment of Sister Chromatid Cohesion

2004 ◽  
Vol 24 (3) ◽  
pp. 1232-1244 ◽  
Author(s):  
Kristin K. Baetz ◽  
Nevan J. Krogan ◽  
Andrew Emili ◽  
Jack Greenblatt ◽  
Philip Hieter
Keyword(s):  
Chromatin Remodeling ◽  
Chromosome Segregation ◽  
High Fidelity ◽  
Chromosome Transmission ◽  
New Genes ◽  
Sister Chromatids ◽  
Chromatin Remodeling Complex ◽  
Chromatid Cohesion ◽  
Spindle Microtubules ◽  
Mitosis And Meiosis

ABSTRACT The budding yeast centromere-kinetochore complex ensures high-fidelity chromosome segregation in mitosis and meiosis by mediating the attachment and movement of chromosomes along spindle microtubules. To identify new genes and pathways whose function impinges on chromosome transmission, we developed a genomic haploinsufficiency modifier screen and used ctf13-30, encoding a mutant core kinetochore protein, as the reference point. We demonstrate through a series of secondary screens that the genomic modifier screen is a successful method for identifying genes that encode nonessential proteins required for the fidelity of chromosome segregation. One gene isolated in our screen was RSC2, a nonessential subunit of the RSC chromatin remodeling complex. rsc2 mutants have defects in both chromosome segregation and cohesion, but the localization of kinetochore proteins to centromeres is not affected. We determined that, in the absence of RSC2, cohesin could still associate with chromosomes but fails to achieve proper cohesion between sister chromatids, indicating that RSC has a role in the establishment of cohesion. In addition, numerous subunits of RSC were affinity purified and a new component of RSC, Rtt102, was identified. Our work indicates that only a subset of the nonessential RSC subunits function in maintaining chromosome transmission fidelity.

scholarly journals The Opposing Actions of Arabidopsis CHROMOSOME TRANSMISSION FIDELITY7 and WINGS APART-LIKE1 and 2 Differ in Mitotic and Meiotic Cells

2016 ◽  
Vol 28 (2) ◽  
pp. 521-536 ◽  
Author(s):  
Kuntal De ◽  
Pablo Bolaños-Villegas ◽  
Sayantan Mitra ◽  
Xiaohui Yang ◽  
Garret Homan ◽  
...  
Keyword(s):  
Chromosome Transmission ◽  
Arabidopsis Chromosome

259: Dna-Repair Genetic Polymorphisms and Prostate Cancer Risk

2005 ◽  
Vol 173 (4S) ◽  
pp. 71-71
Author(s):  
Peter E. Clark ◽  
M. Craig Hall ◽  
Kristin L. Lockett ◽  
Jianfeng Xu ◽  
Sigun L. Zheng ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Dna Repair ◽  
Cancer Risk ◽  
Genetic Polymorphisms ◽  
Prostate Cancer Risk

983: Bladder Cancer Predisposition: A Pathway-Based Approach to DNA Repair and Cell Cycle Control Genes

2006 ◽  
Vol 175 (4S) ◽  
pp. 317-317
Author(s):  
Xifeng Wu ◽  
Jian Gu ◽  
H. Barton Grossman ◽  
Christopher I. Amos ◽  
Carol Etzel ◽  
...  
Keyword(s):  
Cell Cycle ◽  
Bladder Cancer ◽  
Dna Repair ◽  
Cell Cycle Control ◽  
Cancer Predisposition

Drugs Impair Keratinocyte DNA Repair in Culture

2005 ◽  
Vol 36 (7) ◽  
pp. 42
Author(s):  
PATRICE WENDLING
Keyword(s):  
Dna Repair

DNA Repair

2019 ◽  
Keyword(s):  
Dna Repair

DNA Repair and Transcription in Human Premature Aging Disorders

1998 ◽  
Vol 3 (1) ◽  
pp. 11-13 ◽  
Author(s):  
Vilhelm A Bohr ◽  
Grigoiy Dianov ◽  
Adayabalam Balajee ◽  
Alfred May ◽  
David K Orren
Keyword(s):  
Dna Repair ◽  
Premature Aging

DNA repair: Finding a surprising partner

Nature China ◽  
2007 ◽  
Author(s):  
Dangsheng Li
Keyword(s):  
Dna Repair

Tobacco giant sponsors work on DNA repair

Nature ◽  
2006 ◽  
Keyword(s):  
Dna Repair
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