Liberal hemoglobin threshold affects cerebral arterial pulsed Doppler and cardiac output, not cerebral tissue oxygenation: a prospective cohort study in anemic preterm infants

Transfusion ◽  
2019 ◽  
Vol 59 (10) ◽  
pp. 3093-3101 ◽  
Author(s):  
Pranav Jani ◽  
Krista Lowe ◽  
Murray Hinder ◽  
Claire Galea ◽  
Daphne D'Çruz ◽  
...  
Keyword(s):  
Cardiac Output ◽  
Cohort Study ◽  
Preterm Infants ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Tissue Oxygenation ◽  
Pulsed Doppler ◽  
Cerebral Tissue ◽  
Cerebral Tissue Oxygenation ◽  
Hemoglobin Threshold

Changes to hepatic tissue oxygenation, abdominal perfusion and its association with enteral feeding with liberal transfusion threshold in anaemic preterm infants: A prospective cohort study.

Vox Sanguinis ◽  
2020 ◽  
Vol 115 (8) ◽  
pp. 712-721
Author(s):  
Pranav Jani ◽  
Krista Lowe ◽  
Murray Hinder ◽  
Claire Galea ◽  
Daphne D’Çruz ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Prospective Cohort Study ◽  
Enteral Feeding ◽  
Prospective Cohort ◽  
Tissue Oxygenation ◽  
Hepatic Tissue ◽  
Transfusion Threshold ◽  
Liberal Transfusion

scholarly journals Exposure to any antenatal corticosteroids and outcomes in preterm infants by gestational age: prospective cohort study

BMJ ◽  
2017 ◽  
pp. j1039 ◽  
Author(s):  
Colm P Travers ◽  
Reese H Clark ◽  
Alan R Spitzer ◽  
Abhik Das ◽  
Thomas J Garite ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Prospective Cohort Study ◽  
Gestational Age ◽  
Prospective Cohort ◽  
Antenatal Corticosteroids

A Prospective Cohort Study of Fecal miR-223 and miR-451a as Noninvasive and Specific Biomarkers for Diagnosis of Necrotizing Enterocolitis in Preterm Infants

Neonatology ◽  
2020 ◽  
pp. 1-7
Author(s):  
Pak Cheung Ng ◽  
Kathy Yuen Yee Chan ◽  
Hugh Simon Lam ◽  
Raymond Pui On Wong ◽  
Terence Ping Yuen Ma ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Necrotizing Enterocolitis ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Clinical Presentation ◽  
Fecal Calprotectin ◽  
Controlled Study ◽  
Clinical Value ◽  
Predictive Values

<b><i>Objective:</i></b> The objective of this study is to evaluate the usefulness of fecal microRNA (miR)-223 and miR-451a, as novel noninvasive biomarkers for early diagnosis of necrotizing enterocolitis (NEC) in preterm infants. <b><i>Methods:</i></b> Among the top-listed target miRNAs in our previous differential microarray analysis, miR-223 and miR-451a were quantified in a pilot validation case-controlled study (NEC vs. non-NEC/nonsepsis infants; <i>n</i> = 6 in each group). A definitive prospective cohort study (<i>n</i> = 218) further assessed their clinical usefulness as noninvasive and specific diagnostic biomarkers. Fecal calprotectin was quantified in parallel for comparison. <b><i>Results:</i></b> Of 43 proven NEC cases in the cohort study, 24 (55.8%) had fecal samples recovered within the first 3 days of clinical presentation. Fecal miRNA-223 (10.5 fold), miR-451a (4.5 fold), and calprotectin (2.1 fold) concentrations were significant higher in NEC compared with the non-NEC group (<i>p</i> &#x3c; 0.009). Accepting a minimum sensitivity of 0.75, the positive predictive values (PPVs) ranged between 0.19 and 0.20. Combining fecal biomarkers and CRP (Day 1) could marginally increase the PPVs (0.31–0.34) but adversely lowered the sensitivity (0.54–0.63). <b><i>Conclusions:</i></b> Although fecal miRNA biomarkers and calprotectin concentrations were significantly higher in the NEC group, the considerable overlapping of concentrations between groups and low recovery of stool specimens within 72 h of clinical presentation rendered fecal noninvasive tests of limited clinical value in guiding diagnosis of NEC during the acute phase. A further study is underway to evaluate their roles in surveillance for predicting high-risk premature infants developing NEC.

scholarly journals Survival time and its predictors in preterm infants in the post-discharge neonatal period: a prospective cohort study in Busoga Region, Uganda

2020 ◽  
Vol 8 ◽  
pp. S6
Author(s):  
Charles Opio ◽  
Richard Malumba ◽  
Joseph Kagaayi ◽  
Olufemi Ajumobi ◽  
Carol Kamya ◽  
...  
Keyword(s):  
Cohort Study ◽  
Survival Time ◽  
Preterm Infants ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Neonatal Period ◽  
Post Discharge

scholarly journals Foetal haemoglobin, blood transfusion, and retinopathy of prematurity in very preterm infants: a pilot prospective cohort study

Eye ◽  
2017 ◽  
Vol 31 (10) ◽  
pp. 1451-1455 ◽  
Author(s):  
C J Stutchfield ◽  
A Jain ◽  
D Odd ◽  
C Williams ◽  
R Markham
Keyword(s):  
Cohort Study ◽  
Blood Transfusion ◽  
Preterm Infants ◽  
Prospective Cohort Study ◽  
Retinopathy Of Prematurity ◽  
Prospective Cohort ◽  
Foetal Haemoglobin ◽  
Very Preterm Infants ◽  
Very Preterm

scholarly journals Homocysteine levels in preterm infants: is there an association with intraventricular hemorrhage? a prospective cohort study

2007 ◽  
Vol 7 (1) ◽  
Author(s):  
Wendy J Sturtz ◽  
Kathleen H Leef ◽  
Amy B Mackley ◽  
Shailja Sharma ◽  
Teodoro Bottiglieri ◽  
...  
Keyword(s):  
Cohort Study ◽  
Preterm Infants ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Intraventricular Hemorrhage

Remote peripheral tissue oxygenation does not predict postoperative free flap complications in complex head and neck cancer surgery: A prospective cohort study

2017 ◽  
Vol 36 (1) ◽  
pp. 27-31 ◽  
Author(s):  
Marie-Laurence Guye ◽  
Cyrus Motamed ◽  
Sarah Chemam ◽  
Nicolas Leymarie ◽  
Stéphanie Suria ◽  
...  
Keyword(s):  
Cohort Study ◽  
Head And Neck Cancer ◽  
Head And Neck ◽  
Prospective Cohort Study ◽  
Neck Cancer ◽  
Free Flap ◽  
Prospective Cohort ◽  
Tissue Oxygenation ◽  
Cancer Surgery ◽  
Peripheral Tissue
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