A case series of inactivated Japanese encephalitis virus vaccination associated with positive West Nile virus blood donor screening nucleic acid tests

Transfusion ◽  
2020 ◽  
Vol 60 (5) ◽  
pp. 1097-1103
Author(s):  
Steven J. Drews ◽  
Kai Makowski ◽  
Heidi Wood ◽  
Kristina Dimitrova ◽  
Matthew T.S. Yan ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Nucleic Acid ◽  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Blood Donor ◽  
Case Series ◽  
West Nile ◽  
Virus Vaccination ◽  
Donor Screening ◽  
Blood Donor Screening

scholarly journals West Nile Virus Infections Projected from Blood Donor Screening Data, United States, 2003

2006 ◽  
Vol 12 (3) ◽  
pp. 395-402 ◽  
Author(s):  
Michael P. Busch ◽  
David J. Wright ◽  
Brian Custer ◽  
Leslie H. Tobler ◽  
Susan L. Stramer ◽  
...  
Keyword(s):  
United States ◽  
West Nile Virus ◽  
Blood Donor ◽  
Virus Infections ◽  
West Nile ◽  
Donor Screening ◽  
Blood Donor Screening

scholarly journals A replication-defective Japanese encephalitis virus (JEV) vaccine candidate with NS1 deletion confers dual protection against JEV and West Nile virus in mice

npj Vaccines ◽  
2020 ◽  
Vol 5 (1) ◽  
Author(s):  
Na Li ◽  
Zhe-Rui Zhang ◽  
Ya-Nan Zhang ◽  
Jing Liu ◽  
Cheng-Lin Deng ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Vaccine Candidate ◽  
Encephalitis Virus ◽  
West Nile ◽  
Dual Protection

scholarly journals Nonstructural Protein 1-Specific Immunoglobulin M and G Antibody Capture Enzyme-Linked Immunosorbent Assays in Diagnosis of Flaviviral Infections in Humans

2014 ◽  
Vol 53 (2) ◽  
pp. 557-566 ◽  
Author(s):  
Day-Yu Chao ◽  
Jedhan Ucat Galula ◽  
Wen-Fan Shen ◽  
Brent S. Davis ◽  
Gwong-Jen J. Chang
Keyword(s):  
West Nile Virus ◽  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Nonstructural Protein ◽  
Encephalitis Virus ◽  
Igg Antibody ◽  
West Nile ◽  
Dengue Viruses ◽  
Nonstructural Protein 1 ◽  
Antibody Capture

IgM antibody- and IgG antibody-capture enzyme-linked immunosorbent assays (MAC/GAC-ELISAs) targeted at envelope protein (E) of dengue viruses (DENV), West Nile virus, and Japanese encephalitis virus (JEV) are widely used as serodiagnostic tests for presumptive confirmation of viral infection. Antibodies directed against the flavivirus nonstructural protein 1 (NS1) have been proposed as serological markers of natural infections among vaccinated populations. The aim of the current study is to optimize an IgM and IgG antibody-capture ELISA (MAC/GAC-ELISA) to detect anti-NS1 antibodies and compare it with anti-E MAC/GAC-ELISA. Plasmids to express premembrane/envelope (prM/E) or NS1 proteins of six medically important flaviviruses, including dengue viruses (DENV-1 to DENV-4), West Nile virus (WNV), and Japanese encephalitis virus (JEV), were constructed. These plasmids were used for the production of prM/E-containing virus-like particles (VLPs) and secreted NS1 (sNS1) from COS-1 cells. Archived clinical specimens from patients with confirmed DENV, JEV, and WNV infections, along with naive sera, were subjected to NS1-MAC/GAC-ELISAs before or after depletion of anti-prM/E antibodies by preabsorption with or without VLPs. Human serum specimens from previously confirmed DENV infections showed significantly enhanced positive-to-negative (P/N) ratios for NS1-MAC/GAC-ELISAs after the depletion of anti-prM/E antibodies. No statistical differences in sensitivities and specificities were found between the newly developed NS1- and VLP-MAC/GAC-ELISAs. Further application of the assays to WNV- and JEV-infected serum panels showed similar results. A novel approach to perform MAC/GAC-ELISAs for NS1 antibody detection was successfully developed with great potential to differentiate antibodies elicited by the tetravalent chimeric yellow fever-17D/dengue vaccine or DENV infection.

Antibodies generated by immunization with the NS1 protein of West Nile virus confer partial protection against lethal Japanese encephalitis virus challenge

2013 ◽  
Vol 166 (1-2) ◽  
pp. 145-153 ◽  
Author(s):  
EnCheng Sun ◽  
Jing Zhao ◽  
TaoYang ◽  
QingYuan Xu ◽  
YongLi Qin ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Encephalitis Virus ◽  
Ns1 Protein ◽  
West Nile ◽  
Partial Protection ◽  
Virus Challenge

scholarly journals West Nile Fever Characteristics among Viremic Persons Identified through Blood Donor Screening

2010 ◽  
Vol 202 (9) ◽  
pp. 1354-1361 ◽  
Author(s):  
Shimian Zou ◽  
Gregory A. Foster ◽  
Roger Y. Dodd ◽  
Lyle R. Petersen ◽  
Susan L. Stramer
Keyword(s):  
Blood Donor ◽  
West Nile Fever ◽  
West Nile ◽  
Donor Screening ◽  
Blood Donor Screening

Investigation of an algorithm for anti HCV EIA reactivity in blood donor screening in Turkey in the absence of nucleic acid amplification screening

2017 ◽  
Vol 56 (5) ◽  
pp. 732-737 ◽  
Author(s):  
Ayse Esra Karakoc ◽  
Rukiye Berkem ◽  
Hasan Irmak ◽  
Ali Pekcan Demiroz ◽  
Idil Yenicesu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Blood Donor ◽  
Nucleic Acid Amplification ◽  
Donor Screening ◽  
Blood Donor Screening

scholarly journals Neutralizing activities of human immunoglobulin derived from donors in Japan against mosquito-borne flaviviruses, Japanese encephalitis virus, West Nile virus, and dengue virus

2016 ◽  
Vol Volume 10 ◽  
pp. 99-102 ◽  
Author(s):  
Mikihiro Yunoki ◽  
Takeshi Kurosu ◽  
Ritsuko Koketsu ◽  
Kazuo Takahashi ◽  
Yoshinobu Okuno ◽  
...  
Keyword(s):  
West Nile Virus ◽  
Dengue Virus ◽  
Japanese Encephalitis Virus ◽  
Japanese Encephalitis ◽  
Encephalitis Virus ◽  
Human Immunoglobulin ◽  
West Nile ◽  
Virus West Nile
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