scholarly journals Early renal function recovery and long-term graft survival in kidney transplantation

2016 ◽  
Vol 29 (5) ◽  
pp. 619-626 ◽  
Author(s):  
Susan S. Wan ◽  
Marcelo Cantarovich ◽  
Istvan Mucsi ◽  
Dana Baran ◽  
Steven Paraskevas ◽  
...  
2014 ◽  
Vol 98 ◽  
pp. 74-75
Author(s):  
S. Wan ◽  
M. Cantarovich ◽  
I. Mucsi ◽  
D. Baran ◽  
S. Paraskevas ◽  
...  

1986 ◽  
Vol 6 (2) ◽  
pp. 77-79 ◽  
Author(s):  
Giovanni C. Cancarini ◽  
Giuliano Brunori ◽  
Corrado Camerini Silvia ◽  
Brasa Luigi Manili ◽  
Rosario Maiorca

During 1981–1984, at our center 6/75 patients on CAPD and 1/86 on HD demonstrated a recovery of renal function. This and the observation that diuresis was maintained on CAPD, led us to study urine output (UO) and creatinine clearance (CrCI) in 41 patients on CAPD (CAPDp) and 45 on HD (HDp) without the use of diuretics. CAPDp had a decline in diuresis from 1201 ± 379 mI/day to 731 ± 572 (p < 0.01). HDp diuresis decreased from 1233 ± 439 to 438 ± 568 (p < 0.01). Creatinine clearance: HDp 5.8 ± 1.6 ml/min before, 1.3 ± 1.5 after; CAPDp 6.4 ± 2.0 before, 3.9 ± 2.9 after. After one year, HDp showed a significant drop in diuresis; three years passed before CAPDp had significant drop. Patients with glomerulonephritis showed the same trend on HD and CAPD. CAPDp with interstitial nephropathy had a smaller mean annual decrease in UO and CrCI, compared to HDp. CAPDp with nephroangiosclerosis showed less decrease in diuresis compared to HDp. These data confirm that, com pared to HD, CAPD treatment maintains residual renal function even in patients not using diuretics, and suggest that CAPD is a treatment of choice for those considered likely to recover renal function. Some workers have reported a slow decline in residual renal function and diuresis in patients on CAPD (1,2,3). Rottembourg (1), in particular, suggests that diuretics may have helped his patients to maintain diuresis. In 161 dialyzed patients (75 on CAPD, 86 on HD) who started dialysis between 1981 and 1984, six CAPD patients recovered renal function but only one HD patient. This disparity led us to inquire whether when compared to HD, CAPO enables us to maintain satisfactory, long-term diuresis, without the use of diuretics.


2018 ◽  
Vol 199 (4) ◽  
pp. 921-926 ◽  
Author(s):  
Emily C. Zabor ◽  
Helena Furberg ◽  
Byron Lee ◽  
Steven Campbell ◽  
Brian R. Lane ◽  
...  

2009 ◽  
Vol 41 (2) ◽  
pp. 648-650 ◽  
Author(s):  
I. Helal ◽  
E. Abderrahim ◽  
F. Ben Hamida ◽  
M. Ounissi ◽  
S. Essine ◽  
...  

2018 ◽  
Vol 102 ◽  
pp. S711
Author(s):  
Shaifali Sandal ◽  
Marcelo Cantarovich ◽  
Agnihotram Ramankumar ◽  
Nasim Saberi ◽  
Chee Saw ◽  
...  

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kyeong Deok Kim ◽  
Kyo Won Lee ◽  
Sang Jin Kim ◽  
Okjoo Lee ◽  
Manuel Lim ◽  
...  

AbstractThe use of kidneys from donation after brain death (DBD) donors with acute kidney injury (AKI) is a strategy to expand the donor pool. The aim of this study was to evaluate how kidney transplantation (KT) from a donor with AKI affects long-term graft survival in various situations. All patients who underwent KT from DBD donors between June 2003 and April 2016 were retrospectively reviewed. The KDIGO (Kidney Disease: Improving Global Outcomes) criteria were used to classify donor AKI. The cohort included 376 donors (no AKI group, n = 117 [31.1%]; AKI group n = 259 [68.9%]). Death-censored graft survival was similar according to the presence of AKI, AKI severity, and the AKI trend (p = 0.929, p = 0.077, and p = 0.658, respectively). Patients whose donors had AKI who received using low dose (1.5 mg/kg for three days) rabbit anti-thymocyte globulin (r-ATG) as the induction agent had significantly superior death-censored graft survival compared with patients in that group who received basiliximab (p = 0.039). AKI in DBD donors did not affect long-term death-censored graft survival. Low-dose r-ATG may be considered as an induction immunosuppression in recipients receiving kidneys with AKI because it showed better graft survival than basiliximab.


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