Crosstalk between the renal sympathetic nerve and intrarenal angiotensin II modulates proximal tubular sodium reabsorption

2015 ◽  
Vol 100 (5) ◽  
pp. 502-506 ◽  
Author(s):  
Roberto B. Pontes ◽  
Adriana C. C. Girardi ◽  
Erika E. Nishi ◽  
Ruy R. Campos ◽  
Cássia T. Bergamaschi
Keyword(s):  
Angiotensin Ii ◽  
Sympathetic Nerve ◽  
Sodium Reabsorption ◽  
Renal Sympathetic Nerve ◽  
Tubular Sodium Reabsorption ◽  
Proximal Tubular ◽  
Renal Sympathetic

Effect of decreased renal sympathetic nerve activity on renal tubular sodium reabsorption

1978 ◽  
Vol 235 (6) ◽  
pp. F557-F563 ◽  
Author(s):  
E. H. Prosnitz ◽  
G. F. DiBona
Keyword(s):  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Stellate Ganglion ◽  
Sodium Reabsorption ◽  
Nerve Activity ◽  
Renal Sympathetic Nerve Activity ◽  
Renal Sympathetic Nerve ◽  
Tubular Sodium Reabsorption ◽  
Renal Tubular ◽  
Renal Sympathetic

The effect of decreases in renal sympathetic nerve activity on renal tubular sodium reabsorption was examined in anesthetized dogs. Reflex decreases in renal sympathetic nerve activity were produced by left atrial distention and stellate ganglion stimulation. Both interventions produced significant decreases in directly recorded efferent renal sympathetic nerve activity of 42 and 36%, respectively. With renal perfusion pressure held constant, neither glomerular filtration rate nor renal blood flow were significantly altered, but significant and reversible increases in urine flow and sodium excretion occurred. These studies demonstrate that reflex decreases in efferent renal sympathetic nerve activity result in decreases in renal tubular sodium reabsorption without changes in renal hemodynamics.

scholarly journals Electrical stimulation of the renal sympathetic nerve increases NHE3‐mediated sodium reabsorption via angiotensin II AT1 receptor (892.29)

2014 ◽  
Vol 28 (S1) ◽  
Author(s):  
Roberto Pontes ◽  
Renato Crajoinas ◽  
Gláucia Veiga ◽  
Adriana Girardi ◽  
Ruy Campos ◽  
...  
Keyword(s):  
Electrical Stimulation ◽  
Angiotensin Ii ◽  
Sympathetic Nerve ◽  
At1 Receptor ◽  
Sodium Reabsorption ◽  
Renal Sympathetic Nerve ◽  
Renal Sympathetic ◽  
Stimulation Of

Angiotensin II acutely attenuates range of arterial baroreflex control of renal sympathetic nerve activity

2000 ◽  
Vol 279 (4) ◽  
pp. H1804-H1812 ◽  
Author(s):  
Max G. Sanderford ◽  
Vernon S. Bishop
Keyword(s):  
Angiotensin Ii ◽  
Sympathetic Nerve ◽  
Intravenous Infusion ◽  
Sympathetic Nerve Activity ◽  
Ang Ii ◽  
Nerve Activity ◽  
Renal Sympathetic Nerve Activity ◽  
Renal Sympathetic Nerve ◽  
Arterial Blood ◽  
Renal Sympathetic

Acutely increasing peripheral angiotensin II (ANG II) reduces the maximum renal sympathetic nerve activity (RSNA) observed at low mean arterial blood pressures (MAPs). We postulated that this observation could be explained by the action of ANG II to acutely increase arterial blood pressure or increase circulating arginine vasopressin (AVP). Sustained increases in MAP and increases in circulating AVP have previously been shown to attenuate maximum RSNA at low MAP. In conscious rabbits pretreated with an AVP V1 receptor antagonist, we compared the effect of a 5-min intravenous infusion of ANG II (10 and 20 ng · kg−1 · min−1) on the relationship between MAP and RSNA when the acute pressor action of ANG II was left unopposed with that when the acute pressor action of ANG II was opposed by a simultaneous infusion of sodium nitroprusside (SNP). Intravenous infusion of ANG II resulted in a dose-related attenuation of the maximum RSNA observed at low MAP. When the acute pressor action of ANG II was prevented by SNP, maximum RSNA at low MAP was attenuated, similar to that observed when ANG II acutely increased MAP. In contrast, intravertebral infusion of ANG II attenuated maximum RSNA at low MAP significantly more than when administered intravenously. The results of this study suggest that ANG II may act within the central nervous system to acutely attenuate the maximum RSNA observed at low MAP.

scholarly journals Effect of angiotensin II antagonism on canine renal sympathetic nerve function.

Hypertension ◽  
1991 ◽  
Vol 17 (6_pt_2) ◽  
pp. 1127-1134 ◽  
Author(s):  
P C Wong ◽  
S D Hart ◽  
P B Timmermans
Keyword(s):  
Angiotensin Ii ◽  
Sympathetic Nerve ◽  
Nerve Function ◽  
Renal Sympathetic Nerve ◽  
Renal Sympathetic

scholarly journals Inhibition of Renal Sympathetic Nerve Activity of Anesthetized Rats by Intracerebroventricular Administration of Angiotensin II

1989 ◽  
Vol 11 (4) ◽  
pp. 361-370 ◽  
Author(s):  
Xu Ji JIN ◽  
Hiroshi KANNAN ◽  
Yoshiaki HAYASHIDA ◽  
Tadashi NAKAMURA ◽  
Hideaki HIGASHlNO ◽  
...  
Keyword(s):  
Angiotensin Ii ◽  
Sympathetic Nerve ◽  
Sympathetic Nerve Activity ◽  
Intracerebroventricular Administration ◽  
Nerve Activity ◽  
Renal Sympathetic Nerve Activity ◽  
Renal Sympathetic Nerve ◽  
Anesthetized Rats ◽  
Renal Sympathetic

scholarly journals Effect of renal sympathetic nerve stimulation on proximal water and sodium reabsorption.

1976 ◽  
Vol 57 (4) ◽  
pp. 1104-1107 ◽  
Author(s):  
E Bell-Reuss ◽  
D L Trevino ◽  
C W Gottschalk
Keyword(s):  
Nerve Stimulation ◽  
Sympathetic Nerve ◽  
Sodium Reabsorption ◽  
Sympathetic Nerve Stimulation ◽  
Renal Sympathetic Nerve ◽  
Renal Sympathetic
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