Quantitative Characterization of Epicardial Wave Fronts During Regional Ischemia and Elevated Extracellular Potassium Ion Concentration

10.1114/1.136 ◽  
1998 ◽  
Vol 26 (6) ◽  
pp. 1010-1021 ◽  
Author(s):  
Bonnie B. Punske ◽  
Wayne E. Cascio ◽  
Connie Engle ◽  
H. Troy Nagle ◽  
Leonard S. Gettes ◽  
...  
Keyword(s):  
Potassium Ion ◽  
Ion Concentration ◽  
Extracellular Potassium ◽  
Wave Fronts ◽  
Quantitative Characterization ◽  
Regional Ischemia

scholarly journals In Vivo Neocortical [K]o Modulation by Targeted Stimulation of Astrocytes

2021 ◽  
Vol 22 (16) ◽  
pp. 8658
Author(s):  
Azin EbrahimAmini ◽  
Shanthini Mylvaganam ◽  
Paolo Bazzigaluppi ◽  
Mohamad Khazaei ◽  
Alexander Velumian ◽  
...  
Keyword(s):  
Nervous System ◽  
Membrane Potential ◽  
Potassium Ion ◽  
Ion Concentration ◽  
Extracellular Potassium ◽  
Spreading Depolarization ◽  
Potential Tool ◽  
Stimulation Of

A normally functioning nervous system requires normal extracellular potassium ion concentration ([K]o). Throughout the nervous system, several processes, including those of an astrocytic nature, are involved in [K]o regulation. In this study we investigated the effect of astrocytic photostimulation on [K]o. We hypothesized that in vivo photostimulation of eNpHR-expressing astrocytes leads to a decreased [K]o. Using optogenetic and electrophysiological techniques we showed that stimulation of eNpHR-expressing astrocytes resulted in a significantly decreased resting [K]o and evoked K responses. The amplitude of the concomitant spreading depolarization-like events also decreased. Our results imply that astrocytic membrane potential modification could be a potential tool for adjusting the [K]o.

scholarly journals High extracellular potassium ion concentration attenuates the blockade action of ketanserin on Kv1.3 channels expressed in xenopus oocytes

2008 ◽  
Vol 121 (24) ◽  
pp. 2584-2591
Author(s):  
Zhen-tao LIANG ◽  
Xian-pei WANG ◽  
Qiu-tang ZENG ◽  
Yu-hua LIAO ◽  
An-ruo ZOU ◽  
...  
Keyword(s):  
Xenopus Oocytes ◽  
Potassium Ion ◽  
Ion Concentration ◽  
Extracellular Potassium ◽  
Kv1.3 Channels

scholarly journals Computational and Experimental Characterization of a Fluorescent Dye for Detection of Potassium Ion Concentration

2014 ◽  
Vol 118 (42) ◽  
pp. 9837-9843 ◽  
Author(s):  
Matteus Tanha ◽  
Subhasish K. Chakraborty ◽  
Beth Gabris ◽  
Alan S. Waggoner ◽  
Guy Salama ◽  
...  
Keyword(s):  
Potassium Ion ◽  
Fluorescent Dye ◽  
Ion Concentration ◽  
Experimental Characterization

Optical mapping of propagation changes induced by elevated extracellular potassium ion concentration in genetically altered mouse hearts

2004 ◽  
Vol 37 ◽  
pp. 128-134 ◽  
Author(s):  
Bonnie B. Punske ◽  
Stefano Rossi ◽  
Philip Ershler ◽  
Isaac Rasmussen ◽  
E. Dale Abel
Keyword(s):  
Optical Mapping ◽  
Potassium Ion ◽  
Ion Concentration ◽  
Extracellular Potassium
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