Deformations During and Post Stenting of a Diseased Coronary Artery Phantom: An In Vitro Study

Author(s):  
Ronan Finn ◽  
Tim McGloughlin ◽  
Patrick Delassus ◽  
Liam Morris

World-wide, deaths from cardiovascular diseases exceed those caused by cancer, infectious disease and trauma [1]. Coronary stenting is an established treatment for patients with symptomatic coronary artery disease. Although stents reduce restenosis rates in carefully selected lesions, in-stent restenosis remains a recognized clinical problem. Restenosis, defined as “the arterial healing response after injury during transluminal coronary revascularisation” [2], has been the principal drawback of coronary stenting since its conception nearly 30 years ago [3]. While there have been many studies on the short and long term effects of coronary artery stenting, less is known of the injury caused by the balloon and stent during the stenting process. The objective of this study is to fabricate compliant and morphologically realistic models of the right coronary artery (RCA) for preclinical bench-top testing of intraluminal stents, in diseased cases.

2011 ◽  
Vol 363 (1-2) ◽  
pp. 315-322 ◽  
Author(s):  
Yong-Sheng Wang ◽  
Wei Gao ◽  
Hong-Fen Li ◽  
Ze-Mu Wang ◽  
Jun Zhu ◽  
...  

2020 ◽  
Vol 28 ◽  
pp. 1-3
Author(s):  
Alexandre Bonfim ◽  
Ronald Souza ◽  
Sérgio Beraldo ◽  
Frederico Nunes ◽  
Daniel Beraldo

Right coronary artery aneurysms are rare and may result from severe coronary disease, with few cases described in the literature. Mortality is high, and therapy is still controversial. We report the case of a 72-year-old woman with arterial hypertension, and a family history of coronary artery disease, who evolved for 2 months with episodes of palpitations and dyspnea on moderate exertion. During the evaluation, a giant aneurysm was found in the proximal third of the right coronary artery. The patient underwent surgical treatment with grafting of the radial artery to the right coronary artery and ligation of the aneurysmal sac, with good clinical course.


1987 ◽  
Vol 60 (16) ◽  
pp. 1269-1272 ◽  
Author(s):  
Lloyd W. Klein ◽  
Jai B. Agarwal ◽  
Michael B. Herlich ◽  
Therese M. Leary ◽  
Richard H. Helfant

Author(s):  
Shana Tehrani ◽  
Sudhir Rathore ◽  
Vinod Achan

Abstract Background Management of heavily calcified coronary arteries is still a major challenge in interventional cardiology. Inadequate stent expansion in calcific lesions is the single most important predictor of stent thrombosis and in-stent restenosis. Rotational atherectomy (RA) is an important tool to modify the calcium burden but is associated with limitations and requires specific skills. Intravascular lithotripsy (IVL) is a novel technique to treat calcified stenotic lesions and has been proposed as an alternative to RA with promising results. Case summary We report a case of a patient with severely calcified right coronary artery stenosis successfully treated with combination of RA and IVL. Discussion In this case, we demonstrate that the RA and IVL are complementary strategies, not sufficient on their own and not alternative to each other.


2020 ◽  
Vol 2020 ◽  
pp. 1-6
Author(s):  
Sotirios Mitsiadis ◽  
Nikolaos Miaris ◽  
Antonios Dimopoulos ◽  
Anastasios Theodosis-Georgilas ◽  
Spyridon Tsiamis ◽  
...  

Background. While complete revascularization in coronary artery disease is of high priority, the method of implementation in patients with complex coronary lesions and multiple comorbidities is not directed by published guidelines. Case Presentation. A 53-year-old female with a chronic total occlusion of the right coronary artery and a bifurcation lesion of the left anterior descending artery and the first diagonal branch, presented with non-ST elevation myocardial infarction. Her past medical history concerned thymectomy and prior chest radiation for thymoma, myasthenia gravis, peripheral artery disease, and cervical cancer treated with surgery and radiation. Although SYNTAX score II favored surgical revascularization, the interventional pathway was finally successfully followed. However, it was complicated with vessel perforation and tamponade managed with pericardiocentesis. Conclusion. Comorbidities are not all involved in common risk models and require individualization until more evidence comes to light.


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