scholarly journals High-density functional diffuse optical tomography based on frequency-domain measurements improves image quality and spatial resolution

2019 ◽  
Vol 6 (03) ◽  
pp. 1 ◽  
Author(s):  
Matthaios Doulgerakis ◽  
Adam T. Eggebrecht ◽  
Hamid Dehghani
Keyword(s):  
Image Quality ◽  
Frequency Domain ◽  
Spatial Resolution ◽  
Density Functional ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
High Density

scholarly journals Functional imaging of the developing brain with wearable high-density diffuse optical tomography: A new benchmark for infant neuroimaging outside the scanner environment

NeuroImage ◽  
2021 ◽  
Vol 225 ◽  
pp. 117490
Author(s):  
Elisabetta Maria Frijia ◽  
Addison Billing ◽  
Sarah Lloyd-Fox ◽  
Ernesto Vidal Rosas ◽  
Liam Collins-Jones ◽  
...  
Keyword(s):  
Functional Imaging ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
High Density ◽  
Developing Brain

scholarly journals Functional imaging of the human brain using a modular, fibre-less, high-density diffuse optical tomography system

2016 ◽  
Vol 7 (10) ◽  
pp. 4275 ◽  
Author(s):  
Danial Chitnis ◽  
Robert J. Cooper ◽  
Laura Dempsey ◽  
Samuel Powell ◽  
Simone Quaggia ◽  
...  
Keyword(s):  
Human Brain ◽  
Functional Imaging ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
High Density ◽  
Tomography System

scholarly journals Optimal Analysis Method for Dynamic Contrast-Enhanced Diffuse Optical Tomography

2011 ◽  
Vol 2011 ◽  
pp. 1-13 ◽  
Author(s):  
Michael Ghijsen ◽  
Yuting Lin ◽  
Mitchell Hsing ◽  
Orhan Nalcioglu ◽  
Gultekin Gulsen
Keyword(s):  
Spatial Resolution ◽  
Animal Studies ◽  
Imaging Modality ◽  
A Priori ◽  
Optical Tomography ◽  
Diffuse Optical Tomography ◽  
Dynamic Contrast Enhanced ◽  
Promising Tool ◽  
Reconstruction Methods ◽  
Contrast Enhanced

Diffuse Optical Tomography (DOT) is an optical imaging modality that has various clinical applications. However, the spatial resolution and quantitative accuracy of DOT is poor due to strong photon scatting in biological tissue. Structurala prioriinformation from another high spatial resolution imaging modality such as Magnetic Resonance Imaging (MRI) has been demonstrated to significantly improve DOT accuracy. In addition, a contrast agent can be used to obtain differential absorption images of the lesion by using dynamic contrast enhanced DOT (DCE-DOT). This produces a relative absorption map that consists of subtracting a reconstructed baseline image from reconstructed images in which optical contrast is included. In this study, we investigated and compared different reconstruction methods and analysis approaches for regular endogenous DOT and DCE-DOT with and without MR anatomicala prioriinformation for arbitrarily-shaped objects. Our phantom and animal studies have shown that superior image quality and higher accuracy can be achieved using DCE-DOT together with MR structurala prioriinformation. Hence, implementation of a combined MRI-DOT system to image ICG enhancement can potentially be a promising tool for breast cancer imaging.

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