Integrated mid-infrared photonic circuits for label-free biochemical sensing

2016 ◽  
Author(s):  
Pao Tai Lin
Keyword(s):  
Label Free ◽  
Photonic Circuits ◽  
Mid Infrared ◽  
Biochemical Sensing

scholarly journals Graphene-Based Biosensors for Detection of Composite Vibrational Fingerprints in the Mid-Infrared Region

Nanomaterials ◽  
2019 ◽  
Vol 9 (10) ◽  
pp. 1496
Author(s):  
Yijun Cai ◽  
Yanfen Hang ◽  
Yuanguo Zhou ◽  
Jinfeng Zhu ◽  
Jingwen Yang ◽  
...  
Keyword(s):  
Limit Of Detection ◽  
Graphene Nanoribbons ◽  
Infrared Region ◽  
Infrared Range ◽  
Label Free ◽  
Mid Infrared ◽  
Performance Limit ◽  
Wide Range ◽  
Vibrational Signals ◽  
Physical Insight

In this study, a label-free multi-resonant graphene-based biosensor with periodic graphene nanoribbons is proposed for detection of composite vibrational fingerprints in the mid-infrared range. The multiple vibrational signals of biomolecules are simultaneously enhanced and detected by different resonances in the transmission spectrum. Each of the transmission dips can be independently tuned by altering the gating voltage applied on the corresponding graphene nanoribbon. Geometric parameters are investigated and optimized to obtain excellent sensing performance. Limit of detection is also evaluated in an approximation way. Besides, the biosensor can operate in a wide range of incident angles. Electric field intensity distributions are depicted to reveal the physical insight. Moreover, another biosensor based on periodic graphene nanodisks is further proposed, whose performance is insensitive to the polarization of incidence. Our research may have a potential for designing graphene-based biosensor used in many promising bioanalytical and pharmaceutical applications.

scholarly journals Capacitive Field-Effect EIS Chemical Sensors and Biosensors: A Status Report

Sensors ◽  
2020 ◽  
Vol 20 (19) ◽  
pp. 5639 ◽  
Author(s):  
Arshak Poghossian ◽  
Michael J. Schöning
Keyword(s):  
Chemical Sensors ◽  
Field Effect ◽  
Status Report ◽  
Enzymatic Reactions ◽  
Label Free ◽  
Ion Concentrations ◽  
Biochemical Sensing ◽  
Current Trends ◽  
Label Free Detection ◽  
New Generation

Electrolyte-insulator-semiconductor (EIS) field-effect sensors belong to a new generation of electronic chips for biochemical sensing, enabling a direct electronic readout. The review gives an overview on recent advances and current trends in the research and development of chemical sensors and biosensors based on the capacitive field-effect EIS structure—the simplest field-effect device, which represents a biochemically sensitive capacitor. Fundamental concepts, physicochemical phenomena underlying the transduction mechanism and application of capacitive EIS sensors for the detection of pH, ion concentrations, and enzymatic reactions, as well as the label-free detection of charged molecules (nucleic acids, proteins, and polyelectrolytes) and nanoparticles, are presented and discussed.

Mid-Infrared Nanoplasmonics for Label-free Real-time Biosensing of Proteins and Lipid Membranes

2017 ◽  
Author(s):  
Dordaneh Etezadi ◽  
Odeta Limaj ◽  
Nathan J. Wittenberg ◽  
Daniel Rodrigo ◽  
Daehan Yoo ◽  
...  
Keyword(s):  
Real Time ◽  
Lipid Membranes ◽  
Label Free ◽  
Mid Infrared

Label-free biochemical refractive-index tomography of single cells with mid-infrared photothermal effect

2020 ◽  
Author(s):  
Miu Tamamitsu ◽  
Keiichiro Toda ◽  
Hiroyuki Shimada ◽  
Yu Nagashima ◽  
Ryoichi Horisaki ◽  
...  
Keyword(s):  
Refractive Index ◽  
Single Cells ◽  
Photothermal Effect ◽  
Label Free ◽  
Mid Infrared
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