Changes of mean arterial pressure affect spinal cord oxygenation as monitored by an implantable near-infrared spectroscopy sensor in an animal model of acute spinal cord injury (Conference Presentation)

2019 ◽  
Author(s):  
Babak Shadgan ◽  
Allan Fong ◽  
Neda Manouchehri ◽  
Kitty So ◽  
Katelyn Shortt ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Animal Model ◽  
Infrared Spectroscopy ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Near Infrared Spectroscopy ◽  
Near Infrared ◽  
Acute Spinal Cord Injury ◽  
Cord Injury

The Impact of Mean Arterial Pressure on Functional Outcome Post Trauma-Related Acute Spinal Cord Injury: A Scoping Systematic Review of the Human Literature

2016 ◽  
Vol 33 (1) ◽  
pp. 3-15 ◽  
Author(s):  
Behzad Sabit ◽  
Frederick Adam Zeiler ◽  
Neil Berrington
Keyword(s):  
Systematic Review ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Functional Outcome ◽  
Acute Spinal Cord Injury ◽  
Cochrane Library ◽  
Cord Injury ◽  
The Impact

Purpose: To perform a scoping systematic review on the literature surrounding mean arterial pressure (MAP) and functional outcomes post traumatic acute spinal cord injury (ASCI). Methods: We performed a systematic review of the literature via searching MEDLINE, BIOSIS, EMBASE, Global Health, SCOPUS, and Cochrane Library from inception to January 2015. We also performed a handsearch of various published meeting proceedings. Through a 2-step review process, employing 2 independent reviewers, we selected articles for the final review based on predefined inclusion/exclusion criteria. Results: Nine studies were included in the final review. Only 2 were prospective studies. All studies documented some degree of objective functional outcome in relation to MAP posttraumatic ASCI. Four studies documented a relation between higher MAP and improved functional outcome. Five studies failed to show any relationship between MAP and functional outcome. Conclusions: Although no definitive conclusions could be reached based on the data collected, this study does give valuable insight into future avenues of research on the topic of hemodynamic management in traumatic ASCI as well as provides guidelines for refinement of future study design.

Increased vascular resistance in paralyzed legs after spinal cord injury is reversible by training

2002 ◽  
Vol 93 (6) ◽  
pp. 1966-1972 ◽  
Author(s):  
Maria T. E. Hopman ◽  
Jan T. Groothuis ◽  
Marcel Flendrie ◽  
Karin H. L. Gerrits ◽  
Sibrand Houtman
Keyword(s):  
Blood Pressure ◽  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Blood Flow ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Vascular Resistance ◽  
Arterial Blood Flow ◽  
Arterial Blood ◽  
Cord Injury

The purpose of the present study was to determine the effect of a spinal cord injury (SCI) on resting vascular resistance in paralyzed legs in humans. To accomplish this goal, we measured blood pressure and resting flow above and below the lesion (by using venous occlusion plethysmography) in 11 patients with SCI and in 10 healthy controls (C). Relative vascular resistance was calculated as mean arterial pressure in millimeters of mercury divided by the arterial blood flow in milliliters per minute per 100 milliliters of tissue. Arterial blood flow in the sympathetically deprived and paralyzed legs of SCI was significantly lower than leg blood flow in C. Because mean arterial pressure showed no differences between both groups, leg vascular resistance in SCI was significantly higher than in C. Within the SCI group, arterial blood flow was significantly higher and vascular resistance significantly lower in the arms than in the legs. To distinguish between the effect of loss of central neural control vs. deconditioning, a group of nine SCI patients was trained for 6 wk and showed a 30% increase in leg blood flow with unchanged blood pressure levels, indicating a marked reduction in vascular resistance. In conclusion, vascular resistance is increased in the paralyzed legs of individuals with SCI and is reversible by training.

scholarly journals Impact of 2 Distinct Levels of Mean Arterial Pressure on Near-Infrared Spectroscopy During Cardiac Surgery

2019 ◽  
Vol 128 (6) ◽  
pp. 1081-1088 ◽  
Author(s):  
Frederik Holmgaard ◽  
Anne G. Vedel ◽  
Theis Lange ◽  
Jens C. Nilsson ◽  
Hanne B. Ravn
Keyword(s):  
Cardiac Surgery ◽  
Infrared Spectroscopy ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Near Infrared Spectroscopy ◽  
Near Infrared

MEAN ARTERIAL PRESSURE MAINTENANCE FOLLOWING SPINAL CORD INJURY

2020 ◽  
Vol Publish Ahead of Print ◽  
Author(s):  
Jordan A. Weinberg ◽  
S. Harrison Farber ◽  
Louay D. Kalamchi ◽  
Scott T. Brigeman ◽  
Michael A. Bohl ◽  
...  
Keyword(s):  
Spinal Cord ◽  
Spinal Cord Injury ◽  
Mean Arterial Pressure ◽  
Arterial Pressure ◽  
Cord Injury
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