Application of hidden Markov models to biological data mining: a case study

Author(s):  
Michael M. Yin ◽  
Jason T. Wang
2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Daniel Duncan

Abstract Advances in sociophonetic research resulted in features once sorted into discrete bins now being measured continuously. This has implied a shift in what sociolinguists view as the abstract representation of the sociolinguistic variable. When measured discretely, variation is variation in selection: one variant is selected for production, and factors influencing language variation and change are influencing the frequency at which variants are selected. Measured continuously, variation is variation in execution: speakers have a single target for production, which they approximate with varying success. This paper suggests that both approaches can and should be considered in sociophonetic analysis. To that end, I offer the use of hidden Markov models (HMMs) as a novel approach to find speakers’ multiple targets within continuous data. Using the lot vowel among whites in Greater St. Louis as a case study, I compare 2-state and 1-state HMMs constructed at the individual speaker level. Ten of fifty-two speakers’ production is shown to involve the regular use of distinct fronted and backed variants of the vowel. This finding illustrates HMMs’ capacity to allow us to consider variation as both variant selection and execution, making them a useful tool in the analysis of sociophonetic data.


2011 ◽  
pp. 233-255
Author(s):  
Stefano De Luca ◽  
Enrico Memo

The expenses in Health Care are an important portion of the overall expenses of every country, so it is very important to determine if the given cares are the right ones. This work is about a methodology, Health Discoverer, and a consequent software, aimed to disease management and to the measure of appropriateness of cares, and in particular is about the data mining techniques used to verify Clinical Practice Guidelines (CPGs) compliance and the discovery of new, better guidelines. The work is based on Quality Records, episode parsing using Ontologies and Hidden Markov Models.


2021 ◽  
Vol 11 (16) ◽  
pp. 7685
Author(s):  
Alexandre Martins ◽  
Inácio Fonseca ◽  
José Torres Farinha ◽  
João Reis ◽  
António J. Marques Cardoso

The availability maximization is a goal for any organization because the equipment downtime implies high non-production costs and, additionally, the abnormal stopping and restarting usually imply loss of product’s quality. In this way, a method for predicting the equipment’s health state is vital to maintain the production flow as well as to plan maintenance intervention strategies. This paper presents a maintenance prediction approach based on sensing data managed by Hidden Markov Models (HMM). To do so, a diagnosis of drying presses in a pulp industry is used as case study, which is done based on data collected every minute for three years and ten months. This paper presents an approach to manage a multivariate analysis, in this case merging the values of sensors, and optimizing the observable states to insert into a HMM model, which permits to identify three hidden states that characterize the equipment’s health state: “Proper Function”, “Alert state”, and “Equipment Failure”. The research described in this paper demonstrates how an equipment health diagnosis can be made using the HMM, through the collection of observations from various sensors, without information of machine failures occurrences. The approach developed demonstrated to be robust, even the complexity of the system, having the potential to be generalized to any other type of equipment.


Author(s):  
Stefano De Luca ◽  
Enrico Memo

The expenses in Health Care are an important portion of the overall expenses of every country, so it is very important to determine if the given cares are the right ones. This work is about a methodology, Health Discoverer, and a consequent software, aimed to disease management and to the measure of appropriateness of cares, and in particular is about the data mining techniques used to verify Clinical Practice Guidelines (CPGs) compliance and the discovery of new, better guidelines. The work is based on Quality Records, episode parsing using Ontologies and Hidden Markov Models.


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