Multispectral angular domain optical tomography in scattering media with argon and diode laser sources

Author(s):  
Paulman K. Y. Chan ◽  
Fartash Vasefi ◽  
Glenn H. Chapman ◽  
Bozena Kaminska ◽  
Nick Pfeiffer
2008 ◽  
Vol 16 (19) ◽  
pp. 14456 ◽  
Author(s):  
Fartash Vasefi ◽  
Bozena Kaminska ◽  
Paulman K. Y. Chan ◽  
Glenn H. Chapman

2008 ◽  
Vol 2 (2) ◽  
Author(s):  
M. Cassel-Engquist ◽  
L. Persson ◽  
K. Svanberg ◽  
S. Svanberg

We have developed a technique to measure gas non-intrusive in scattering media, such as human tissue. The technique was first demonstrated for test samples in 2001 by our group and utilizes diode laser absorption spectroscopy to monitor molecular oxygen and water vapor. The focus of medical application has been on sinuses, both maxillary and frontal sinuses and the potential of the technique has been shown on volunteers. A spin-off company named GasPorOx AB has been formed with the aim to develop a product used to improve the diagnosis of the sinus infections. A portable fiber-guided system has been developed and is used in an ongoing initial clinical trial in collaboration with the Ear, Nose and Throat Clinic, the Oncology and Diagnostic radiology clinics at the Lund University Hospital.


Author(s):  
Olivier Balima ◽  
Joan Boulanger ◽  
Andre´ Charette ◽  
Daniel Marceau

This paper presents a numerical study of optical tomography in frequency domain for the reconstruction of optical properties of scattering and absorbing media with collimated irradiation light sources. The forward model is a least square finite element formulation of the collimated irradiation problem where the intensity is separated into its collimated and scattered parts. This model does not use any empirical stabilization and moreover the collimated source direction is taken into account. The inversion uses a gradient type minimization method where the gradient is computed through an adjoint formulation. Scaling is used to avoid numerical round errors, as the output readings at detectors are very low. Numerical reconstructions of optical properties of absorbing and scattering media with simulated data (noised and noise-free) are achieved in a complex geometry with satisfactory results. The results show that complex geometries are well handled with the proposed method.


2005 ◽  
Vol 86 (19) ◽  
pp. 191101 ◽  
Author(s):  
Oliver Casel ◽  
Harry Fuchs ◽  
Marc A. Tremont ◽  
Dirk Woll ◽  
Richard Wallenstein

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