Polarization sensitive optical coherence tomography for quantifying the severity of natural caries lesions on occlusal surfaces

2007 ◽  
Author(s):  
Daniel Fried ◽  
Patara Ngaotheppitak ◽  
Cynthia L. Darling ◽  
Chi M. Ho
2006 ◽  
Vol 40 (2) ◽  
pp. 81-89 ◽  
Author(s):  
R.S. Jones ◽  
C.L. Darling ◽  
J.D.B. Featherstone ◽  
D. Fried

PLoS ONE ◽  
2021 ◽  
Vol 16 (7) ◽  
pp. e0254217
Author(s):  
Marcia Cristina Dias-Moraes ◽  
Pedro Arthur Augusto Castro ◽  
Daísa Lima Pereira ◽  
Patrícia Aparecida Ana ◽  
Anderson Zanardi Freitas ◽  
...  

Objective This in vitro study characterized and monitored, by Optical Coherence Tomography (OCT) and Fourier Transformed Infrared Spectroscopy (FTIR), the effects of the association of acidulated phosphate fluoride gel (APF-gel) and Nd:YAG (neodymiun:yttrium-aluminum-garnet) laser, as sequencial treatments, in the prevention of incipient enamel caries lesions. Methods 120 human enamel samples were randomized into 3 groups (n = 40): APF-gel (1.23% F-, 4 min.); Laser+APF (Nd:YAG laser irradiation—0.6W, 84.9J/cm2, 10Hz, followed by APF-gel); and APF+Laser (APF-gel followed by laser irradiation). The samples were subjected to a 15-day pH-cycling, evaluated by OCT (quantification of optical attenuation coefficient–OAC) and FTIR (analysis of carbonate and phosphate content) before treatments, after treatments, and on the 5th, 10th and 15th days of pH-cycling. The statistical analysis was performed (α = 5%). Results The Optical Attenuation Coefficient (OAC) assessed by OCT increases with the progression of demineralization, and the Laser+APF presented the highest values of OAC in 10th and 15th days of pH-cycling. Nd:YAG decreased the carbonate content after treatment regardless of the application order of the APF-gel, while APF-gel did not interfere in the composition of enamel. The carbonate content was also changed in the first 5 days of the pH-cycling in all groups. Conclusion Nd:YAG laser irradiation before or after the application of APF-gel did not influence the appearance of incipient caries lesions, showing no synergistic effect. Regardless of the application order of the APF-gel, laser irradiation reduces the carbonate content of the enamel, which also changes during the demineralization process. However, irradiation before the application of APF-gel increased the speed of progression of the lesions, which positively impacts public health as it can prevent caries disease, even in high risk individuals. OCT and FTIR are suitable for assessing this effect.


2002 ◽  
Author(s):  
Daniel Fried ◽  
John Xie ◽  
Sahar Shafi ◽  
John D. B. Featherstone ◽  
Thomas Breunig ◽  
...  

Sensors ◽  
2020 ◽  
Vol 20 (6) ◽  
pp. 1659 ◽  
Author(s):  
Minh N. Luong ◽  
Yasushi Shimada ◽  
Kazuyuki Araki ◽  
Masahiro Yoshiyama ◽  
Junji Tagami ◽  
...  

Detecting the extent of occlusal caries is a clinically important but challenging task required for treatment decision making. The aim of this study was to assess the diagnostic power of 3D swept-source optical coherence tomography (OCT) for evaluation of occlusal caries in comparison with X-ray radiography. Extracted human molars not exhibiting American Dental Association (ADA) criteria advanced caries were mounted in a silicone block and digital dental radiographs were captured from the buccal side. Subsequently, occlusal surfaces were scanned with a prototype Yoshida Dental OCT. Thirteen examiners evaluated the presence and extent of caries on radiographs and dynamically sliced 3D OCT video images, using a 4 level scale—0: intact; 1: enamel demineralization without cavitation; 2: enamel caries with cavitation; 3: dentin caries with or without cavitation. Sensitivity, specificity and area under operating characteristic curves (Az) were statistically analyzed (α = 0.05). Reliability analysis showed an excellent agreement among the 13 examiners for both methods. The OCT presented a significantly higher sensitivity and Az value for the detection of caries compared to radiographs (p < 0.05). Radiography showed especially low sensitivity for dentin caries (0–2 versus 3). Dynamic slicing of 3D OCT volumes is a powerful adjunct tool to visual inspection to diagnose the dentin occlusal caries in vitro.


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