In vivo
 dosimetry with optically stimulated dosimeters and RTQA2 radiochromic film for intraoperative radiotherapy of the breast

[ACCESS RESTRICTED TO THE UNIVERSITY OF MISSOURI AT REQUEST OF AUTHOR.] Advance treatment techniques, such as IMRT and dynamic conformal arc delivery, are novel radiation treatment procedures at the forefront of accurate and precise radiotherapy. However, the risk of suboptimal treatment resulting in injury is far greater with these techniques due to their complexity. An in vivo quality assurance system is the most appropriate validation of the delivered dose to the patient from these techniques. The intent of this research is to propose an in vivo dosimetry quality assurance procedure using radiochromic film. This research proved that radiochromic in vivo dosimetry is a viable method of detecting spatial patient specific errors in radiotherapy; however, the process is time consuming and not sensitive enough for dosimetric errors associated with weight change. Although time consuming, in vivo radiochromic dosimetry is an attractive alternative for small cancer centers and developing countries without the large startup capital to acquire the electronic portal imaging device necessary for EPID in vivo dosimetry.

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OC-0487: In vivo dosimetry using MOSFET and radiochromic films in intraoperative radiotherapy for breast cancer treatment

Radiotherapy and Oncology ◽

10.1016/s0167-8140(15)32793-6 ◽

2013 ◽

Vol 106 ◽

pp. S189-S190

Author(s):

F. Cavagnetto ◽

L. Ferri ◽

S. Agostinelli ◽

M. Gusinu ◽

M. Guenzi ◽

...

Keyword(s):

Breast Cancer ◽

Cancer Treatment ◽

Intraoperative Radiotherapy ◽

Breast Cancer Treatment ◽

In Vivo Dosimetry ◽

Radiochromic Films

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Radiochromic film in vivo dosimetry predicts early the risk of acute skin toxicity for brachytherapy partial breast irradiation

Physics in Medicine and Biology ◽

10.1088/1361-6560/ab7c2f ◽

2020 ◽

Vol 65 (8) ◽

pp. 085001

Author(s):

Gerson M Struik ◽

Jeremy Godart ◽

Taco M Klem ◽

Thalat T Monajemi ◽

James Robar ◽

...

Keyword(s):

Skin Toxicity ◽

Radiochromic Film ◽

In Vivo Dosimetry ◽

Partial Breast Irradiation ◽

Breast Irradiation ◽

Acute Skin Toxicity

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Is Electron Beam Intraoperative Radiotherapy (ELIOT) Safe in Pregnant Women with Early Breast Cancer? In Vivo Dosimetry to Assess Fetal Dose

Annals of Surgical Oncology ◽

10.1245/s10434-008-0172-z ◽

2009 ◽

Vol 16 (1) ◽

Cited By ~ 17

Author(s):

Viviana Galimberti ◽

Mario Ciocca ◽

Maria Cristina Leonardi ◽

Vanna Zanagnolo ◽

Baratella Paola ◽

...

Keyword(s):

Breast Cancer ◽

Electron Beam ◽

Pregnant Women ◽

Early Breast Cancer ◽

Intraoperative Radiotherapy ◽

In Vivo Dosimetry ◽

Fetal Dose

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Evaluation and clinical implementation of in vivo dosimetry for kV radiotherapy using radiochromic film and micro-silica bead thermoluminescent detectors

Physica Medica ◽

10.1016/j.ejmp.2017.08.009 ◽

2017 ◽

Vol 42 ◽

pp. 47-54 ◽

Cited By ~ 2

Author(s):

Antony L. Palmer ◽

Shakardokht M. Jafari ◽

Ioanna Mone ◽

Sarah Muscat

Keyword(s):

Radiochromic Film ◽

In Vivo Dosimetry ◽

Clinical Implementation ◽

Silica Bead ◽

Micro Silica ◽

Thermoluminescent Detectors

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PO-1350: In vivo dosimetry with XR-RV3 radiochromic films in intraoperative radiotherapy of the breast

Radiotherapy and Oncology ◽

10.1016/s0167-8140(21)01369-4 ◽

2020 ◽

Vol 152 ◽

pp. S715-S716

Author(s):

S. Lozares ◽

A. Gandía ◽

J.A. Font ◽

D. Villa ◽

V. Alba ◽

...

Keyword(s):

Intraoperative Radiotherapy ◽

In Vivo Dosimetry ◽

Radiochromic Films

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Electron Beam Intraoperative Radiotherapy (ELIOT) in Pregnant Women with Breast Cancer: From in Vivo Dosimetry to Clinical Practice

Breast Care ◽

10.1159/000479862 ◽

2017 ◽

Vol 12 (6) ◽

pp. 396-400 ◽

Cited By ~ 4

Author(s):

Maria Leonardi ◽

Agnese Cecconi ◽

Rosa Luraschi ◽

Elena Rondi ◽

Federica Cattani ◽

...

Keyword(s):

Breast Cancer ◽

Electron Beam ◽

Pregnant Women ◽

Intraoperative Radiotherapy ◽

Pregnant Patient ◽

Breast Conserving Surgery ◽

In Vivo Dosimetry ◽

Breast Cancer Patients ◽

Tumor Bed

Background: The aim of this study was to confirm our preliminary results with in vivo dosimetry in non-pregnant breast cancer patients receiving electron beam intraoperative radiotherapy (ELIOT) and to report on the first treatment in a pregnant woman. Patients and Methods: Following our previous experience, 5 non-pregnant patients receiving ELIOT to the tumor bed after breast-conserving surgery (BCS) were studied with thermoluminescent dosimeters positioned in the subdiaphragmatic region, within the uterus, and in the ovarian region. In December 2011, the first pregnant breast cancer patient underwent BCS and ELIOT (21 Gy at 90% isodose) during the 15th week of gestation. Results: The mean dose to the subdiaphragmatic external region in the 5 non-pregnant patients was 5.57 mGy, while pelvic measurements were below 1 mGy. The actual dosimetry of the pregnant patient showed a mean subdiaphragmatic dose of 4.34 mGy, a mean suprapubic dose of 1.64 mGy, and mean ovarian doses of 1.48 mGy (right-sided) and 1.44 mGy (left-sided). The expected dose to the fetus was estimated as 0.84 mGy (0.004% of the prescribed dose). Conclusion: ELIOT as an anticipated boost to the breast could be considered in pregnant women in the early second trimester, postponing whole-breast irradiation after delivery.

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