WE-AB-BRA-10: Systematic Assessment of a Novel Image Similarity Parameterization Metric for Fully Automated Quantification of Deformable Image Registration Accuracy

We aimed to clarify the accuracy of rigid image registration and deformable image registration (DIR) in carbon-ion radiotherapy (CIRT) for pancreatic cancer. Six patients with pancreatic cancer who were treated with passive irradiation CIRT were enrolled. Three registration patterns were evaluated: treatment planning computed tomography images (TPCT) to CT images acquired in the treatment room (IRCT) in the supine position, TPCT to IRCT in the prone position, and TPCT in the supine position to the prone position. After warping the contours of the original CT images to the destination CT images using deformation matrices from the registration, the warped delineated contours on the destination CT images were compared with the original ones using mean displacement to agreement (MDA). Four contours (clinical target volume (CTV), gross tumor volume (GTV), stomach, duodenum) and four registration algorithms (rigid image registration [RIR], intensity-based DIR [iDIR], contour-based DIR [cDIR], and a hybrid iDIR-cDIR ([hDIR]) were evaluated. The means ± standard deviation of the MDAs of all contours for RIR, iDIR, cDIR, and hDIR were 3.40 ± 3.30, 2.2 1± 2.48, 1.46 ± 1.49, and 1.46 ± 1.37 mm, respectively. There were significant differences between RIR and iDIR, and between RIR/iDIR and cDIR/hDIR. For the pancreatic cancer patient images, cDIR and hDIR had better accuracy than RIR and iDIR.

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SU-FF-J-97: A Novel Metric for Automatic Assessment of Deformable Image Registration Accuracy

Medical Physics ◽

10.1118/1.1997643 ◽

2005 ◽

Vol 32 (6Part5) ◽

pp. 1942-1942

Author(s):

K Brock ◽

J Moseley ◽

D Jaffray

Keyword(s):

Image Registration ◽

Deformable Image Registration ◽

Automatic Assessment ◽

Registration Accuracy

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SU-E-J-92: Validating Dose Uncertainty Estimates Produced by AUTODIRECT, An Automated Program to Evaluate Deformable Image Registration Accuracy

Medical Physics ◽

10.1118/1.4924179 ◽

2015 ◽

Vol 42 (6Part8) ◽

pp. 3285-3285

Author(s):

H Kim ◽

J Chen ◽

J Pouliot ◽

J Pukala ◽

N Kirby

Keyword(s):

Image Registration ◽

Deformable Image Registration ◽

Registration Accuracy ◽

Uncertainty Estimates ◽

Dose Uncertainty

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Effect of Deformation Methods on the Accuracy of Deformable Image Registration From Kilovoltage CT to Tomotherapy Megavoltage CT

Technology in Cancer Research & Treatment ◽

10.1177/1533033818821186 ◽

2019 ◽

Vol 18 ◽

pp. 153303381882118 ◽

Cited By ~ 2

Author(s):

Wannapha Nobnop ◽

Imjai Chitapanarux ◽

Somsak Wanwilairat ◽

Ekkasit Tharavichitkul ◽

Vicharn Lorvidhaya ◽

...

Keyword(s):

Computed Tomography ◽

Nasopharyngeal Carcinoma ◽

Image Registration ◽

Deformable Image Registration ◽

Adaptive Radiotherapy ◽

Deformation Field ◽

Registration Accuracy ◽

Deformation Method ◽

Computed Tomography Images ◽

Significant Difference

Introduction: The registration accuracy of megavoltage computed tomography images is limited by low image contrast when compared to that of kilovoltage computed tomography images. Such issues may degrade the deformable image registration accuracy. This study evaluates the deformable image registration from kilovoltage to megavoltage images when using different deformation methods and assessing nasopharyngeal carcinoma patient images. Methods: The kilovoltage and the megavoltage images from the first day and the 20th fractions of the treatment day of 12 patients with nasopharyngeal carcinoma were used to evaluate the deformable image registration application. The deformable image registration image procedures were classified into 3 groups, including kilovoltage to kilovoltage, megavoltage to megavoltage, and kilovoltage to megavoltage. Three deformable image registration methods were employed using the deformable image registration and adaptive radiotherapy software. The validation was compared by volume-based, intensity-based, and deformation field analyses. Results: The use of different deformation methods greatly affected the deformable image registration accuracy from kilovoltage to megavoltage. The asymmetric transformation with the demon method was significantly better than other methods and illustrated satisfactory value for adaptive applications. The deformable image registration accuracy from kilovoltage to megavoltage showed no significant difference from the kilovoltage to kilovoltage images when using the appropriate method of registration. Conclusions: The choice of deformation method should be considered when applying the deformable image registration from kilovoltage to megavoltage images. The deformable image registration accuracy from kilovoltage to megavoltage revealed a good agreement in terms of intensity-based, volume-based, and deformation field analyses and showed clinically useful methods for nasopharyngeal carcinoma adaptive radiotherapy in tomotherapy applications.

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