A Method for Measuring Surface Tension

1948 ◽  
Vol 16 (5) ◽  
pp. 305-307
Author(s):  
A. A. El-Karim
2008 ◽  
Vol 273 (1-2) ◽  
pp. 87-91 ◽  
Author(s):  
Dequan Shi ◽  
Guili Gao ◽  
Dayong Li ◽  
Jingwei Dong ◽  
Lihua Wang

1993 ◽  
Vol 295 (1) ◽  
pp. 19-22 ◽  
Author(s):  
T A Merritt ◽  
J D Amirkhanian ◽  
H Helbock ◽  
B Halliwell ◽  
C E Cross

The reactive species hypochlorous acid (HOCl/OCl-) is a major product of the respiratory burst in activated neutrophils. We studied the effects of HOCl/OCl- on human surfactant and upon surfactants Survanta, KL4 and Exosurf, utilizing a pulsating surfactometer for measuring surface tension. HOCl/OCl- induced a marked dose-dependent decrease in the surface-tension-lowering activity of human surfactant. The surfactant containing surfactant proteins B and C (Survanta) was less sensitive; however, synthetic surfactants with or without peptides were not affected by HOCl/OCl- (KL4, Exosurf). Ascorbic acid and GSH protected human surfactant against inactivation by HOCl/OC1-. We suggest that HOCl/OCl- produced by activated phagocytes in the alveolar compartment of the lung could damage endogenous surfactant and affect the function of exogenously administered natural or other surfactants, especially if ascorbic acid and GSH levels in the lung lining fluids are subnormal, as is known to be the case in some inflammatory lung diseases.


It is known that the surface tension of solutions of many hydrophilic colloids such as proteins, saponins and soaps, is comparatively high when the surface is newly formed and that it falls rapidly at first and then more slowly (du Noüy, 1919, 1926; Wilson and Ries, 1923; Harkins and Zollmann, 1926). This fall may continue for many hours and measurements of the surface tension of such a solution cannot therefore have much significance unless either the surface has reached equilibrium or the age of the surface is known. The method which is most frequently used for the study of the surface tension of such solutions is that which depends on the measurement of the force exerted by the liquid on a wire ring which is placed on the surface and then pulled away (du Noüy, 1926; Harkins and Jordan, 1930). It is the purpose of this paper and which is especially suitable for these studies. Certain curious reactions of the surface of solutions of stretching will also be described.


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