A Novel Mechanism for Polychlorinated Biphenyl-Induced Decrease in Serum Thyroxine Level in Rats

2007 ◽  
Vol 35 (10) ◽  
pp. 1949-1955 ◽  
Author(s):  
Yoshihisa Kato ◽  
Shin-ichi Ikushiro ◽  
Rie Takiguchi ◽  
Koichi Haraguchi ◽  
Nobuyuki Koga ◽  
...  
Keyword(s):  
Polychlorinated Biphenyl ◽  
Serum Thyroxine ◽  
Thyroxine Level

Polychlorinated Biphenyl-Mediated Decrease in Serum Thyroxine Level in Rodents

2009 ◽  
Vol 38 (4) ◽  
pp. 697-704 ◽  
Author(s):  
Yoshihisa Kato ◽  
Koichi Haraguchi ◽  
Yuriko Ito ◽  
Aki Fujii ◽  
Tomoaki Yamazaki ◽  
...  
Keyword(s):  
Polychlorinated Biphenyl ◽  
Serum Thyroxine ◽  
Thyroxine Level

DECREASE IN SERUM THYROXINE LEVEL BY PHENOBARBITAL IN RATS IS NOT NECESSARILY DEPENDENT ON INCREASE IN HEPATIC UDP-GLUCURONOSYLTRANSFERASE

2005 ◽  
Vol 33 (11) ◽  
pp. 1608-1612 ◽  
Author(s):  
Yoshihisa Kato ◽  
Hiroshi Suzuki ◽  
Shinichi Ikushiro ◽  
Shizuo Yamada ◽  
Masakuni Degawa
Keyword(s):  
Serum Thyroxine ◽  
Thyroxine Level ◽  
Udp Glucuronosyltransferase

4-Hydroxy-2,2′,3,4′,5,5′,6-heptachlorobiphenyl-Mediated Decrease in Serum Thyroxine Level in Mice Occurs through Increase in Accumulation of Thyroxine in the Liver

2009 ◽  
Vol 37 (10) ◽  
pp. 2095-2102 ◽  
Author(s):  
Yoshihisa Kato ◽  
Koichi Haraguchi ◽  
Makiko Kubota ◽  
Yoshiki Seto ◽  
Shin-ichi Ikushiro ◽  
...  
Keyword(s):  
Serum Thyroxine ◽  
Thyroxine Level

Serum thyroxine level and cognitive decline in euthyroid older women

Neurology ◽  
2002 ◽  
Vol 58 (7) ◽  
pp. 1055-1061 ◽  
Author(s):  
S. Volpato ◽  
J. M. Guralnik ◽  
L. P. Fried ◽  
A. T. Remaley ◽  
A. R. Cappola ◽  
...  
Keyword(s):  
Cognitive Decline ◽  
Older Women ◽  
Serum Thyroxine ◽  
Thyroxine Level

scholarly journals Basal serum thyroxine level should guide initial thyroxine replacement dose in neonates with congenital hypothyroidism

2020 ◽  
Vol 0 (0) ◽  
pp. 0-0
Author(s):  
Ceren Günbey ◽  
Alev Özön ◽  
E. Nazlı Gönç ◽  
Ayfer Alikaşifoğlu ◽  
Sevilay Karahan ◽  
...  
Keyword(s):  
Congenital Hypothyroidism ◽  
Serum Thyroxine ◽  
Thyroxine Level ◽  
Basal Serum ◽  
Thyroxine Replacement

A possible mechanism for the decrease in serum thyroxine level by phenobarbital in rodents

2010 ◽  
Vol 249 (3) ◽  
pp. 238-246 ◽  
Author(s):  
Yoshihisa Kato ◽  
Hiroshi Suzuki ◽  
Koichi Haraguchi ◽  
Shinichi Ikushiro ◽  
Yoshihiko Ito ◽  
...  
Keyword(s):  
Serum Thyroxine ◽  
Thyroxine Level

Goitres in rats fed polychlorinated biphenyls

1977 ◽  
Vol 55 (2) ◽  
pp. 288-292 ◽  
Author(s):  
C. H. Bastomsky
Keyword(s):  
Thyroid Hormone ◽  
Polychlorinated Biphenyls ◽  
Thyroid Hormones ◽  
Polychlorinated Biphenyl ◽  
Serum Proteins ◽  
Elevated Serum ◽  
High Serum ◽  
Serum Thyroxine ◽  
Low Serum

Rats fed a polychlorinated biphenyl (PCB) mixture in a high- or low-iodine diet (HID or LID, respectively) for 15 days had thyroid enlargement, low serum thyroxine (T4), and high serum thyrotropin concentrations. Although binding of thyroid hormones to serum proteins was reduced in PCB-fed animals, the free T4 index (reflecting free T4 in serum) was less in these rats. Both serum triiodothyronine (T3) and the free T3 index were elevated in rats fed PCB in HID. LID-maintained rats had elevated serum T3 concentrations but the free T3 index was similar to that in HID-fed rats, owing to enhanced binding of thyroid hormone to serum proteins. Addition of PCB to LID reduced serum T3 levels but did not alter the free T3 index because binding was less. In rats fed HID containing PCB, thyroid 131I uptake was increased.

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