Altered Human CYP3A4 Activity Caused by Antley-Bixler Syndrome-Related Variants of NADPH-Cytochrome P450 Oxidoreductase Measured in a Robust In Vitro System

Daniela Moutinho; Christopher C. Marohnic; Satya P. Panda; José Rueff; Bettie Sue Masters; Michel Kranendonk

doi:10.1124/dmd.111.042820

Altered Human CYP3A4 Activity Caused by Antley-Bixler Syndrome-Related Variants of NADPH-Cytochrome P450 Oxidoreductase Measured in a Robust In Vitro System

Drug Metabolism and Disposition ◽

10.1124/dmd.111.042820 ◽

2012 ◽

Vol 40 (4) ◽

pp. 754-760 ◽

Cited By ~ 19

Author(s):

Daniela Moutinho ◽

Christopher C. Marohnic ◽

Satya P. Panda ◽

José Rueff ◽

Bettie Sue Masters ◽

...

Keyword(s):

Cytochrome P450 ◽

Cyp3a4 Activity ◽

In Vitro System ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Amphipol-facilitated Elucidation of the Functional Tetrameric Complex of Full-length Cytochrome P450 CYP2B4 and NADPH-Cytochrome-P450 Oxidoreductase

Journal of Biological Chemistry ◽

10.1016/j.jbc.2021.100645 ◽

2021 ◽

pp. 100645

Author(s):

Shen Cheng ◽

Zhiyuan Bo ◽

Paul Hollenberg ◽

Yoichi Osawa ◽

Haoming Zhang

Keyword(s):

Cytochrome P450 ◽

Full Length ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase ◽

Tetrameric Complex

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NADPH-cytochrome P450 oxidoreductase from the chicken (Gallus gallus): Sequence characterization, functional expression and kinetic study

Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology ◽

10.1016/j.cbpc.2010.08.005 ◽

2011 ◽

Vol 153 (1) ◽

pp. 53-59 ◽

Cited By ~ 1

Author(s):

Xiaojie Zhou ◽

Mei Li ◽

Chengfa Sheng ◽

Xinghui Qiu

Keyword(s):

Cytochrome P450 ◽

Kinetic Study ◽

Functional Expression ◽

Gallus Gallus ◽

Sequence Characterization ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Regulation of NADPH‐cytochrome P450 oxidoreductase by glucocorticoids in rat liver

The FASEB Journal ◽

10.1096/fasebj.27.1_supplement.lb627 ◽

2013 ◽

Vol 27 (S1) ◽

Author(s):

Alex Vonk ◽

David S Riddick

Keyword(s):

Cytochrome P450 ◽

Rat Liver ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Drosophila melanogaster NADPH–cytochrome P450 oxidoreductase: pronounced expression in antennae may be related toodorantclearance

Gene ◽

10.1016/s0378-1119(96)00851-7 ◽

1997 ◽

Vol 189 (2) ◽

pp. 213-219 ◽

Cited By ~ 56

Author(s):

Bernhard T Hovemann ◽

Frank Sehlmeyer ◽

Jochen Malz

Keyword(s):

Drosophila Melanogaster ◽

Cytochrome P450 ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Stable Expression of Human Cytochrome P450 3A4 in Conjunction with Human NADPH-Cytochrome P450 Oxidoreductase in V79 Chinese Hamster Cells

Archives of Biochemistry and Biophysics ◽

10.1006/abbi.1996.0345 ◽

1996 ◽

Vol 332 (2) ◽

pp. 295-304 ◽

Cited By ~ 29

Author(s):

Anneliese Schneider ◽

Wolfgang A. Schmalix ◽

Vasanthi Siruguri ◽

Els M. de Groene ◽

G.Jean Horbach ◽

...

Keyword(s):

Cytochrome P450 ◽

Chinese Hamster ◽

Stable Expression ◽

Cytochrome P450 3A4 ◽

Chinese Hamster Cells ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Human Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Mechanistic Studies on the Reductive Half-reaction of NADPH-Cytochrome P450 Oxidoreductase

Journal of Biological Chemistry ◽

10.1074/jbc.274.9.5391 ◽

1999 ◽

Vol 274 (9) ◽

pp. 5391-5398 ◽

Cited By ~ 46

Author(s):

Anna L. Shen ◽

Daniel S. Sem ◽

Charles B. Kasper

Keyword(s):

Cytochrome P450 ◽

Mechanistic Studies ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Impact on CYP19A1 activity by mutations in NADPH cytochrome P450 oxidoreductase

The Journal of Steroid Biochemistry and Molecular Biology ◽

10.1016/j.jsbmb.2016.03.031 ◽

2017 ◽

Vol 165 ◽

pp. 64-70 ◽

Cited By ~ 15

Author(s):

Christa E. Flück ◽

Amit V. Pandey

Keyword(s):

Cytochrome P450 ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Cytochrome P450 Oxidoreductase

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Isolation of a New Mouse cDNA Clone: Hybrid Form of Cytochrome P450 2b10 and NADPH-Cytochrome P450 Oxidoreductase

Biochemical and Biophysical Research Communications ◽

10.1006/bbrc.1996.1447 ◽

1996 ◽

Vol 226 (3) ◽

pp. 900-905 ◽

Cited By ~ 6

Author(s):

Marie Damon ◽

Alain Fautrel ◽

Nathalie Marc ◽

André Guillouzo ◽

Laurent Corcos

Keyword(s):

Cytochrome P450 ◽

Cdna Clone ◽

Hybrid Form ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Mouse Cdna ◽

Cytochrome P450 Oxidoreductase

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In vitro fertilization-frozen embryo transfer in a patient with cytochrome P450 oxidoreductase deficiency: a case report

Gynecological Endocrinology ◽

10.1080/09513590.2017.1393663 ◽

2017 ◽

Vol 34 (5) ◽

pp. 385-388 ◽

Cited By ~ 4

Author(s):

Tianran Song ◽

Bin Wang ◽

Huan Chen ◽

Jingjing Zhu ◽

Haixiang Sun

Keyword(s):

Cytochrome P450 ◽

Case Report ◽

In Vitro Fertilization ◽

Embryo Transfer ◽

Frozen Embryo Transfer ◽

Vitro Fertilization ◽

P450 Oxidoreductase ◽

Cytochrome P450 Oxidoreductase

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Role of glucocorticoid receptor and pregnane X receptor in dexamethasone induction of rat hepatic aryl hydrocarbon receptor nuclear translocator and NADPH‐cytochrome P450 oxidoreductase (LB597)

The FASEB Journal ◽

10.1096/fasebj.28.1_supplement.lb597 ◽

2014 ◽

Vol 28 (S1) ◽

Author(s):

David Riddick ◽

Sarah Hunter ◽

Alex Vonk

Keyword(s):

Cytochrome P450 ◽

Glucocorticoid Receptor ◽

Aryl Hydrocarbon Receptor ◽

Pregnane X Receptor ◽

P450 Oxidoreductase ◽

Nadph Cytochrome ◽

Aryl Hydrocarbon ◽

Cytochrome P450 Oxidoreductase

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