Cytochrome P4503A Does Not Mediate the Interaction between Methadone and Ritonavir-Lopinavir

Drug Metabolism and Disposition ◽

10.1124/dmd.113.053991 ◽

2013 ◽

Vol 41 (12) ◽

pp. 2166-2174 ◽

Author(s):

Evan D. Kharasch ◽

Kristi Stubbert

Keyword(s):

Cytochrome P4503a

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Metabolism of digoxin and digoxigenin digitoxosides in rat liver microsomes: involvement of cytochrome P4503A

Xenobiotica ◽

10.1080/004982599238722 ◽

1999 ◽

Vol 29 (2) ◽

pp. 171-185 ◽

Author(s):

LAURENT SALPHATI

Keyword(s):

Rat Liver ◽

Liver Microsomes ◽

Rat Liver Microsomes ◽

Cytochrome P4503a

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Disposition and miotic effects of oral alfentanil: A potential noninvasive probe for first-pass cytochrome P4503A activity

Clinical Pharmacology & Therapeutics ◽

10.1067/mcp.2003.30 ◽

2003 ◽

Vol 73 (3) ◽

pp. 199-208 ◽

Author(s):

E Kharasch

Keyword(s):

Cytochrome P4503a

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Suppression of intestinal and hepatic cytochrome P4503A in murineToxoplasma infection. Effects ofN-acetylcysteine andNG-monomethyl-L-arginine on the hepatic suppression

Xenobiotica ◽

10.3109/00498259609046717 ◽

1996 ◽

Vol 26 (4) ◽

pp. 381-394 ◽

Author(s):

M. Berg-candolfi ◽

E. Candolfi ◽

L. Z. Benet

Keyword(s):

Cytochrome P4503a ◽

Hepatic Cytochrome

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Methadone metabolism and clearance are induced by nelfinavir despite inhibition of cytochrome P4503A (CYP3A) activity

Drug and Alcohol Dependence ◽

10.1016/j.drugalcdep.2008.12.009 ◽

2009 ◽

Vol 101 (3) ◽

pp. 158-168 ◽

Author(s):

Evan D. Kharasch ◽

Alysa Walker ◽

Dale Whittington ◽

Christine Hoffer ◽

Pamela Sheffels Bedynek

Keyword(s):

Cyp3a Activity ◽

Cytochrome P4503a ◽

Methadone Metabolism

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Identification of cytochrome P4503A as the major enzyme sub-family responsible for the metabolism of 22,23-dihydro-13-O-[(2-methoxyethoxy)methyl]avermectin B1aglycone by rat liver microsomes

Xenobiotica ◽

10.1080/004982597239967 ◽

1997 ◽

Vol 27 (10) ◽

pp. 985-994 ◽

Author(s):

Z. ZENG* ◽

N. W. ANDREW ◽

B. A. HALLEY

Keyword(s):

Rat Liver ◽

Liver Microsomes ◽

Rat Liver Microsomes ◽

Cytochrome P4503a

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Involvement of cytochrome P4503A in catalysis of tamoxifen activation and covalent binding to rat and human liver microsomes

Carcinogenesis ◽

10.1093/carcin/15.12.2715 ◽

1994 ◽

Vol 15 (12) ◽

pp. 2715-2720 ◽

Author(s):

Chitra Mani ◽

Robin Pearce ◽

Andrew Parkinson ◽

David Kupfer

Keyword(s):

Human Liver ◽

Covalent Binding ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Cytochrome P4503a

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Effects of the Administration of Spiramycin and Tiamulin on In Vivo Complex Formation and Hepatic Cytochrome P4503A (CYP3A)-dependent Monooxygenases in Rabbits

Veterinary Research Communications ◽

10.1023/b:verc.0000014184.56266.1a ◽

2003 ◽

Vol 27 ◽

pp. 377-379 ◽

Author(s):

M. Cantiello ◽

A. Zaghini ◽

C. Nebbia ◽

M. Carletti ◽

M. Dacasto ◽

...

Keyword(s):

Complex Formation ◽

Cytochrome P4503a ◽

Hepatic Cytochrome

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P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.93.9.4001 ◽

1996 ◽

Vol 93 (9) ◽

pp. 4001-4005 ◽

Author(s):

E. G. Schuetz ◽

A. H. Schinkel ◽

M. V. Relling ◽

J. D. Schuetz

Keyword(s):

Inducible Expression ◽

Major Determinant ◽

P Glycoprotein ◽

Cytochrome P4503a

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Short‐chain fatty acids oppositely altered expressions and functions of intestinal cytochrome P4503A and P‐glycoprotein and affected pharmacokinetics of verapamil following oral administration to rats

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.13215 ◽

2019 ◽

Vol 72 (3) ◽

pp. 448-460 ◽

Author(s):

Jiaxin Zhang ◽

Qiushi Xie ◽

Weimin Kong ◽

Zhongjian Wang ◽

Shuting Wang ◽

...

Keyword(s):

Fatty Acids ◽

Oral Administration ◽

Short Chain Fatty Acids ◽

Short Chain ◽

P Glycoprotein ◽

Cytochrome P4503a ◽

Chain Fatty Acids

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Effect of the ethinylestradiol/levonorgestrel combined oral contraceptive on the activity of cytochrome P4503A in obese women

British Journal of Clinical Pharmacology ◽

10.1111/j.1365-2125.2012.04209.x ◽

2012 ◽

Vol 74 (3) ◽

pp. 510-514 ◽

Author(s):

Alison Edelman ◽

Myrna Munar ◽

Miriam R. Elman ◽

Dennis Koop ◽

Ganesh Cherala

Keyword(s):

Oral Contraceptive ◽

Obese Women ◽

Combined Oral Contraceptive ◽

Cytochrome P4503a

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