P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.

E. G. Schuetz; A. H. Schinkel; M. V. Relling; J. D. Schuetz

doi:10.1073/pnas.93.9.4001

P-glycoprotein: a major determinant of rifampicin-inducible expression of cytochrome P4503A in mice and humans.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.93.9.4001 ◽

1996 ◽

Vol 93 (9) ◽

pp. 4001-4005 ◽

Cited By ~ 185

Author(s):

E. G. Schuetz ◽

A. H. Schinkel ◽

M. V. Relling ◽

J. D. Schuetz

Keyword(s):

Inducible Expression ◽

Major Determinant ◽

P Glycoprotein ◽

Cytochrome P4503a

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Short‐chain fatty acids oppositely altered expressions and functions of intestinal cytochrome P4503A and P‐glycoprotein and affected pharmacokinetics of verapamil following oral administration to rats

Journal of Pharmacy and Pharmacology ◽

10.1111/jphp.13215 ◽

2019 ◽

Vol 72 (3) ◽

pp. 448-460 ◽

Cited By ~ 1

Author(s):

Jiaxin Zhang ◽

Qiushi Xie ◽

Weimin Kong ◽

Zhongjian Wang ◽

Shuting Wang ◽

...

Keyword(s):

Fatty Acids ◽

Oral Administration ◽

Short Chain Fatty Acids ◽

Short Chain ◽

P Glycoprotein ◽

Cytochrome P4503a ◽

Chain Fatty Acids

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P-Glycoprotein Is a Major Determinant of Norbuprenorphine Brain Exposure and Antinociception

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.112.193433 ◽

2012 ◽

Vol 343 (1) ◽

pp. 53-61 ◽

Cited By ~ 41

Author(s):

Sarah M. Brown ◽

Scott D. Campbell ◽

Amanda Crafford ◽

Karen J. Regina ◽

Michael J. Holtzman ◽

...

Keyword(s):

Major Determinant ◽

P Glycoprotein ◽

Brain Exposure

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Evaluation of First-Pass Cytochrome P4503A (CYP3A) and P-Glycoprotein Activities Using Alfentanil and Fexofenadine in Combination

The Journal of Clinical Pharmacology ◽

10.1177/0091270004269705 ◽

2005 ◽

Vol 45 (1) ◽

pp. 79-88 ◽

Cited By ~ 24

Author(s):

Evan D. Kharasch ◽

Alysa Walker ◽

Christine Hoffer ◽

Pamela Sheffels

Keyword(s):

P Glycoprotein ◽

First Pass ◽

Cytochrome P4503a

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Evaluation of First-Pass Cytochrome P4503A (CYP3A) and P-glycoprotein Activities Using Felodipine and Hesperetin in Combination in Wistar Rats and Everted Rat Gut Sacs in Vitro

Phytotherapy Research ◽

10.1002/ptr.5040 ◽

2013 ◽

Vol 28 (5) ◽

pp. 699-705 ◽

Cited By ~ 15

Author(s):

V. Sridhar ◽

M. Surya Sandeep ◽

P. Ravindra Babu ◽

K. Naveen Babu

Keyword(s):

Wistar Rats ◽

P Glycoprotein ◽

First Pass ◽

Cytochrome P4503a ◽

Rat Gut

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Danshen extract does not alter pharmacokinetics of docetaxel and clopidogrel, reflecting its negligible potential in P-glycoprotein- and cytochrome P4503A-mediated herb–drug interactions

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2011.03.031 ◽

2011 ◽

Vol 410 (1-2) ◽

pp. 68-74 ◽

Cited By ~ 17

Author(s):

Joo Hyun Lee ◽

Yong-Jun Shin ◽

Hye Jin Kim ◽

Ju-Hee Oh ◽

Young Pyo Jang ◽

...

Keyword(s):

Drug Interactions ◽

P Glycoprotein ◽

Cytochrome P4503a

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P-glycoprotein and its inducible expression in three bivalve species after exposure to Prorocentrum lima

Aquatic Toxicology ◽

10.1016/j.aquatox.2015.10.012 ◽

2015 ◽

Vol 169 ◽

pp. 123-132 ◽

Cited By ~ 13

Author(s):

Lu Huang ◽

Su-Li Liu ◽

Jian-Wei Zheng ◽

Hong-Ye Li ◽

Jie-Sheng Liu ◽

...

Keyword(s):

Inducible Expression ◽

Bivalve Species ◽

Prorocentrum Lima ◽

P Glycoprotein

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Pharmacogenetics of Clozapine: In Vivo Role of Cytochrome P450 Isoforms and P-Glycoprotein

Pharmacopsychiatry ◽

10.1055/s-0028-1088256 ◽

2008 ◽

Vol 41 (05) ◽

Author(s):

E Jaquenoud-Sirot ◽

B Knezevic ◽

G Perla Morena ◽

P Baumann ◽

CB Eap

Keyword(s):

Cytochrome P450 ◽

P Glycoprotein ◽

Cytochrome P450 Isoforms

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Inhibition of P-glycoprotein at the blood brain barrier by phytochemicals derived from traditional Chinese medicine

Planta Medica ◽

10.1055/s-0029-1234258 ◽

2009 ◽

Vol 75 (09) ◽

Cited By ~ 1

Author(s):

T Efferth

Keyword(s):

Chinese Medicine ◽

Traditional Chinese Medicine ◽

Blood Brain Barrier ◽

Brain Barrier ◽

P Glycoprotein ◽

Blood Brain

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Influence of P-glycoprotein (P-gp) induction on the pharmacokinetics of risperidone and paliperidone in mouse brain

Pharmacopsychiatry ◽

10.1055/s-0029-1240137 ◽

2009 ◽

Vol 42 (05) ◽

Author(s):

D Holthoewer ◽

C Hiemke ◽

U Schmitt

Keyword(s):

Mouse Brain ◽

Glycoprotein P ◽

P Glycoprotein

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Structure activity-relationships of P-Glycoprotein modulation using a small library of macrocyclic lathyrane diterpenes

Planta Medica ◽

10.1055/s-0032-1320394 ◽

2012 ◽

Vol 78 (11) ◽

Author(s):

M Reis ◽

RJ Ferreira ◽

MMM Santos ◽

DJVA dos Santos ◽

J Molnár ◽

...

Keyword(s):

Structure Activity Relationships ◽

Structure Activity ◽

P Glycoprotein

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