THE RELATION BETWEEN THE URINARY EXCRETION OF CITRIC ACID AND CALCIUM; ITS IMPLICATIONS FOR URINARY CALCIUM STONE FORMATION

Science ◽  
1942 ◽  
Vol 96 (2504) ◽  
pp. 587-588 ◽  
Author(s):  
E. SHORR ◽  
T. P. ALMY ◽  
M. H. SLOAN ◽  
H. TAUSSKY ◽  
V. TOSCANI
1996 ◽  
Vol 24 (3) ◽  
pp. 141-147 ◽  
Author(s):  
Rajkiran ◽  
A. K. Pendse ◽  
R. Ghosh ◽  
D. V. S. S. Ramavataram ◽  
P. P. Singh

1997 ◽  
Vol 263 (1) ◽  
pp. 43-55 ◽  
Author(s):  
F Grases ◽  
L Garcı́a-Ferragut ◽  
A Costa-Bauzá ◽  
A Conte ◽  
A Garcı́a-Raja

2018 ◽  
Vol 38 (3) ◽  
pp. 267-272
Author(s):  
Víctor M. García Nieto ◽  
Xochitl Illian Pérez Bastida ◽  
María Salvador Cañibano ◽  
Victoria E. García Rodríguez ◽  
Margarita Monge Zamorano ◽  
...  

1999 ◽  
Vol 10 (5) ◽  
pp. 1007-1013
Author(s):  
PATRICK SCOTT ◽  
DENIS OUIMET ◽  
LUC VALIQUETTE ◽  
GÉRALD GUAY ◽  
YANICK PROULX ◽  
...  

Abstract. Calcium is the principal crystalline constituent in up to 80% of kidney stones. Epidemiologic studies have suggested that genetic predisposition plays a major role in the etiology of this condition. This study evaluates by a candidate-gene approach whether the vitamin D receptor (VDR) locus on chromosome 12q12-14 is implicated in idiopathic hypercalciuria and calcium nephrolithiasis in a cohort of 47 French Canadian pedigrees. These comprised 54 sibships with a total of 303 pairs of siblings concordant for ≥1 stone episode. Evidence is provided for linkage to nephrolithiasis with microsatellite marker D12S339 (near the VDR locus, P = 0.01), as well as with flanking markers (D12S1663: P = 0.03 and D12S368: P = 0.01). Inclusion of unaffected sibs in the analyses also supported evidence for linkage. Quantitative trait linkage analysis of urinary calcium excretion yielded linkage to some, but not all, markers. This appears to be the first study to suggest linkage for idiopathic calcium stone formation.


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