scholarly journals Lactic Acid Polymers as Biodegradable Carriers of Fluoroquinolones: An In Vitro Study

1999 ◽  
Vol 43 (3) ◽  
pp. 714-716 ◽  
Author(s):  
Kyriaki Kanellakopoulou ◽  
Maria Kolia ◽  
Antonios Anastassiadis ◽  
Themistoklis Korakis ◽  
Evangelos J. Giamarellos-Bourboulis ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Lactic Acid ◽  
Biodegradable Polymer ◽  
Chronic Osteomyelitis ◽  
In Vitro Study ◽  
Vitro Study ◽  
Bone Infections

ABSTRACT A biodegradable polymer of dl-dilactide that facilitates release of ciprofloxacin or pefloxacin at levels exceeding MICs for the causative microorganisms of chronic osteomyelitis is described. Duration and peak of release were found to depend on the molecular weight of the polymer. Its characteristics make it promising for treating chronic bone infections.

In vitro study on electrospun lecithin-based poly (L-lactic acid) scaffolds and their biocompatibility

2020 ◽  
Vol 31 (17) ◽  
pp. 2285-2298
Author(s):  
Zhonghua Xu ◽  
Peng Liu ◽  
Hongyin Li ◽  
Mingkui Zhang ◽  
Qingyu Wu
Keyword(s):  
Lactic Acid ◽  
In Vitro Study ◽  
Vitro Study

Anticancer properties of low molecular weight oat beta-glucan – An in vitro study

2015 ◽  
Vol 80 ◽  
pp. 23-28 ◽  
Author(s):  
Anna Choromanska ◽  
Julita Kulbacka ◽  
Nina Rembialkowska ◽  
Justyna Pilat ◽  
Remigiusz Oledzki ◽  
...  
Keyword(s):  
Molecular Weight ◽  
In Vitro Study ◽  
Vitro Study ◽  
Low Molecular Weight ◽  
Beta Glucan ◽  
Anticancer Properties

Evaluation of the effect of a heat-killed lactic acid bacterium, Enterococcus faecalis 2001, on oral candidiasis

2019 ◽  
Vol 10 (6) ◽  
pp. 661-669
Author(s):  
T. Yamazaki ◽  
R. Ushikoshi-Nakayama ◽  
K. Shirone ◽  
M. Suzuki ◽  
S. Abe ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Clinical Study ◽  
Enterococcus Faecalis ◽  
Mycelial Growth ◽  
Oral Candidiasis ◽  
In Vitro Study ◽  
Inhibitory Effect ◽  
Vitro Study ◽  
Oral Candida

The effect of a preparation of heat-killed Gram-positive lactic acid bacteria Enterococcus faecalis 2001 (EF-2001) on oral candidiasis was evaluated by two studies. An in vitro study was performed to assess the inhibitory effect on mycelial growth of Candida strains isolated from a patient with oral candidiasis, and a clinical study was done in patients with oral candidiasis. In the in vitro study, EF-2001 inhibited mycelial growth of IT-1, a Candida strain isolated from a patient with oral candidiasis, at concentrations ≥2.34×109 cells/ml. An open clinical study was performed in 13 patients with oral candidiasis. The subjects took a powder containing 7.5×1011 heat-killed EF-2001 once a day before bedtime for seven consecutive days. In 11 of the 12 patients available for analysis (92%), the oral Candida load (cfu/swab) showed a significant decrease (P=0.01079, d=-0.437). There was a 55% decrease of Candida albicans and a 93.8% decrease of Candida glabrata. The following symptoms showed significant improvement: tinnitus (P=0.048, d=-0.462), cold feeling (P=0.048, d=-0.463), and depression (P=0.019, d=-0.34). In addition, 4 out of 26 oral symptoms tended to improve. These results suggest that EF-2001 significantly decreased the oral Candida load in patients with oral candidiasis by inhibiting mycelial growth and that EF-2001 is an effective treatment for oral candidiasis.

scholarly journals e0170 The sensitivity of different reagents for laboratory monitoring of low molecular weight heparin: an in vitro study

Heart ◽  
2010 ◽  
Vol 96 (Suppl 3) ◽  
pp. A54-A55
Author(s):  
S. Xu-Bo ◽  
H. Da-Yi ◽  
W. Jian-Qi ◽  
C. Zhe ◽  
Y. Hai-Rong ◽  
...  
Keyword(s):  
Molecular Weight ◽  
Low Molecular Weight Heparin ◽  
In Vitro Study ◽  
Vitro Study ◽  
Low Molecular Weight ◽  
Laboratory Monitoring

scholarly journals Colloidal gold-loaded, biodegradable, polymer-based stavudine nanoparticle uptake by macrophages: an in vitro study

2012 ◽  
pp. 6049 ◽  
Author(s):  
Biswajit Mukherjee ◽  
Sumit Basu ◽  
Samrat Roy Chowdhury ◽  
Paramita Paul ◽  
Rupak Choudhury ◽  
...  
Keyword(s):  
Biodegradable Polymer ◽  
Colloidal Gold ◽  
In Vitro Study ◽  
Vitro Study ◽  
Nanoparticle Uptake

In vitro study of poly(lactic acid) pin degradation

Polymer ◽  
1999 ◽  
Vol 40 (23) ◽  
pp. 6465-6473 ◽  
Author(s):  
E.A.R Duek ◽  
C.A.C Zavaglia ◽  
W.D Belangero
Keyword(s):  
Lactic Acid ◽  
In Vitro Study ◽  
Vitro Study ◽  
Poly Lactic Acid

An in vitro study on the key features of Poly L-lactic acid/biphasic calcium phosphate scaffolds fabricated via DLP 3D printing for bone grafting

2020 ◽  
Vol 141 ◽  
pp. 110057
Author(s):  
Arvin Bagheri Saed ◽  
Amir Hossein Behravesh ◽  
Sadegh Hasannia ◽  
Behnam Akhoundi ◽  
Seyyed Kaveh Hedayati ◽  
...  
Keyword(s):  
Lactic Acid ◽  
Calcium Phosphate ◽  
3D Printing ◽  
Bone Grafting ◽  
Biphasic Calcium Phosphate ◽  
In Vitro Study ◽  
Vitro Study ◽  
Key Features
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