Novel, Rapid, and Inexpensive Cell-Based Quantification of Antimalarial Drug Efficacy
2004 ◽
Vol 48
(5)
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pp. 1807-1810
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Keyword(s):
ABSTRACT We report on the development of a new SYBR Green I-based plate assay for analyzing the activities of antimalarial drugs against intraerythrocytic Plasmodium falciparum. This assay is considerably faster, less labor-intensive, and less expensive than conventional radiotracer (e.g., [3H]hypoxanthine and [3H]ethanolamine)-based assays or P. falciparum lactate dehydrogenase activity-based assays. The assay significantly improves the pace at which antimalarial drug discovery efforts may proceed.
1993 ◽
Vol 48
(2)
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pp. 205-210
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1995 ◽
Vol 80
(2)
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pp. 260-271
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2012 ◽
Vol 1
(2)
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pp. 1-3
2008 ◽
Vol 112
(46)
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pp. 18034-18038
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2000 ◽
Vol 91
(1-2)
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pp. 129-140
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2006 ◽
Vol 31
(4)
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pp. 541-548
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