scholarly journals Genital tract infection with Chlamydia trachomatis fails to induce protective immunity in gamma interferon receptor-deficient mice despite a strong local immunoglobulin A response.

1997 ◽  
Vol 65 (3) ◽  
pp. 1032-1044 ◽  
Author(s):  
M Johansson ◽  
K Schön ◽  
M Ward ◽  
N Lycke
1999 ◽  
Vol 67 (10) ◽  
pp. 5518-5521 ◽  
Author(s):  
James I. Ito ◽  
Joseph M. Lyons

ABSTRACT Earlier investigations have not shown an important role for gamma interferon (IFN-γ) in the early clearance of chlamydial infection from the murine female genital tract. In a model using a human genital isolate of Chlamydia trachomatis in IFN-γ and IFN-γ receptor knockout mice, we were able to demonstrate a major role for IFN-γ in mediating control of infection throughout the course of infection.


Vaccine ◽  
2011 ◽  
Vol 29 (35) ◽  
pp. 5994-6001 ◽  
Author(s):  
Marien I. de Jonge ◽  
Sander A.S. Keizer ◽  
Hicham M. el Moussaoui ◽  
Lieke van Dorsten ◽  
Rima Azzawi ◽  
...  

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