scholarly journals Genetic characterization of the pnuC gene, which encodes a component of the nicotinamide mononucleotide transport system in Salmonella typhimurium.

1989 ◽  
Vol 171 (8) ◽  
pp. 4402-4409 ◽  
Author(s):  
N Zhu ◽  
B M Olivera ◽  
J R Roth
Keyword(s):  
Salmonella Typhimurium ◽  
Transport System ◽  
Genetic Characterization ◽  
Nicotinamide Mononucleotide

scholarly journals Biological and genetic characterization of TnphoA mutants of Salmonella typhimurium TML in the context of gastroenteritis.

1995 ◽  
Vol 63 (3) ◽  
pp. 762-769 ◽  
Author(s):  
J Lodge ◽  
G R Douce ◽  
I I Amin ◽  
A J Bolton ◽  
G D Martin ◽  
...  
Keyword(s):  
Salmonella Typhimurium ◽  
Genetic Characterization

scholarly journals GENETIC CHARACTERIZATION OF THE SufJ FRAMESHIFT SUPPRESSOR IN SALMONELLA TYPHIMURIUM

Genetics ◽  
1983 ◽  
Vol 103 (1) ◽  
pp. 31-42
Author(s):  
Lionello Bossi ◽  
Tadahiko Kohno ◽  
John R Roth
Keyword(s):  
Salmonella Typhimurium ◽  
Genetic Characterization ◽  
Trna Modification ◽  
Wild Type ◽  
Frameshift Mutations ◽  
Carbamyl Phosphate Synthetase ◽  
Trna Structure ◽  
Trna Species ◽  
Allele Specific

ABSTRACT A new suppressor of +1 frameshift mutations has been isolated in Salmonella typhimurium. This suppressor, sufJ, maps at minute 89 on the Salmonella genetic map between the argH and rpo(rif) loci, closely linked to the gene for the ochre suppressor tyrU(supM). The suppressor mutation is dominant to its wild-type allele, consistent with the suppressor phenotype being caused by an altered tRNA species. The sufJ map position coincides with that of a threonine tRNA(ACC/U) gene; the suppressor has been shown to read the related fourbase codons ACCU, ACCC, ACCA.—The ability of sufJ to correct one particular mutation depends on the presence of a hisT mutation which causes a defect in tRNA modification. This requirement is allele specific, since other frameshift mutations can be corrected by sufJ regardless of the state of the hisT locus.—Strains carrying both a sufJ and a hisT mutation are acutely sensitive to growth inhibition by uracil; the inhibition is reversed by arginine. This behavior is characteristic of strains with mutations affecting the arginine-uracil biosynthetic enzyme carbamyl phosphate synthetase. The combination of two mutations affecting tRNA structure may reduce expression of the structural gene for this enzyme (pyrA).

scholarly journals Genetic characterization of the araE gene in Salmonella typhimurium lt2.

1981 ◽  
Vol 146 (1) ◽  
pp. 298-304 ◽  
Author(s):  
J H Lee ◽  
S Al-Zarban ◽  
G Wilcox
Keyword(s):  
Salmonella Typhimurium ◽  
Genetic Characterization
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