scholarly journals Helicobacter pylori Infection in Infants and Toddlers in South America: Concordance between [13C]Urea Breath Test and Monoclonal H. pylori Stool Antigen Test

2013 ◽  
Vol 51 (11) ◽  
pp. 3735-3740 ◽  
Author(s):  
Dulciene Maria Magalhães Queiroz ◽  
Mayuko Saito ◽  
Gifone Aguiar Rocha ◽  
Andreia Maria Camargos Rocha ◽  
Fabrício Freire Melo ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
South America ◽  
Breath Test ◽  
Urea Breath Test ◽  
Infants And Toddlers ◽  
Antigen Test ◽  
Stool Antigen Test ◽  
Stool Antigen ◽  
13C Urea Breath Test ◽  
H Pylori

scholarly journals Evaluation of [13C]Urea Breath Test and Helicobacter pylori Stool Antigen Test for Diagnosis of H. pylori Infection in Children from a Developing Country

2003 ◽  
Vol 41 (7) ◽  
pp. 3334-3335 ◽  
Author(s):  
L. d. C. C. Cardinali ◽  
G. A. Rocha ◽  
A. M. C. Rocha ◽  
S. B. de Moura ◽  
T. de Figueiredo Soares ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Developing Country ◽  
Breath Test ◽  
Urea Breath Test ◽  
Antigen Test ◽  
Stool Antigen Test ◽  
Stool Antigen ◽  
13C Urea Breath Test ◽  
H Pylori

scholarly journals The Use of 13C-Urea Breath Test for Non-Invasive Diagnosis of Helicobacter pylori Infection in Comparison to Endoscopy and Stool Antigen Test

Diagnostics ◽  
2020 ◽  
Vol 10 (7) ◽  
pp. 448
Author(s):  
Hamed Alzoubi ◽  
Asma’a Al-Mnayyis ◽  
Ibrahim Al rfoa ◽  
Amin Aqel ◽  
Mohammad Abu-Lubad ◽  
...  
Keyword(s):  
Breath Test ◽  
Eradication Therapy ◽  
Urea Breath Test ◽  
P Value ◽  
Antigen Test ◽  
Stool Antigen Test ◽  
Non Invasive ◽  
Stool Antigen ◽  
13C Urea Breath Test ◽  
H Pylori

Helicobacter pylori (H. pylori) can cause gastritis, peptic ulcer diseases and gastric carcinoma. Endoscopy as the gold standard method of diagnosis is an invasive procedure that might not be suitable in all scenarios. Therefore, this first study in Jordan aimed to assess the non-invasive 13C urea breath test (UBT) and stool antigen test for diagnosis of H. pylori infection and the successfulness of eradication therapy as alternatives for endoscopy. Hence, a total of 30 patients attending the endoscopy units at Alkarak teaching hospital were asked to complete a questionnaire with demographic and clinical data. They were then tested for H. pylori using 13C UBT and H. pylori stool antigen before having endoscopy. Another 30 patients who were positive for H. pylori by endoscopy were tested using both tests 6 weeks post eradication therapy. Results showed that the rate of H. pylori detection using endoscopy was 56.7% (17/30). Heartburns (82.3%, p value = 0.019), epigastric pain (88.2%, p value = 0.007) and vomiting (70.5%, p value = 0.02) were the most significant symptoms. Family history of peptic ulcer diseases was significantly associated with an increased risk for having a H. pylori positive result (p value = 0.02). Compared to endoscopy, the sensitivity of 13C UBT for the diagnosis of H. pylori was 94.1% (16/17), while it was 76.5% (13/17) for the stool antigen test. The specificity of both tests was equal (76.9%). However, the positive predictive and negative predictive values (84.2% and 90.9%) for 13C UBT were higher than those (81.3% and 71.4%) for the stool antigen test. The accuracy of 13C UBT was 86.7% compared to 76.7% for the stool antigen test. There was an 87% agreement (20 patients out of 23) between both tests when used to assess success of the eradication therapy. In conclusion, the 13C UBT was found to be more sensitive and accurate than the stool antigen test when used for diagnosis; furthermore, it has a comparable outcome to the stool antigen test in assessing the successfulness of the eradication treatment.

Comparison between the 13C-urea breath test and stool antigen test for the diagnosis of childhood Helicobacter pylori infection

2004 ◽  
Vol 39 (11) ◽  
pp. 1045-1050 ◽  
Author(s):  
Seiichi Kato ◽  
Keiko Nakayama ◽  
Takanori Minoura ◽  
Mutsuko Konno ◽  
Hitoshi Tajiri ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Breath Test ◽  
Urea Breath Test ◽  
Helicobacter Pylori Infection ◽  
Antigen Test ◽  
Stool Antigen Test ◽  
Stool Antigen ◽  
13C Urea Breath Test

scholarly journals Validation of a rapid stool antigen test for diagnosis of Helicobacter pylori infection

2010 ◽  
Vol 52 (3) ◽  
pp. 125-128 ◽  
Author(s):  
Joyce Matie Kinoshita da Silva ◽  
Cibele Aparecida Villares ◽  
Maria do Socorro Monteiro ◽  
Carlos Colaúto ◽  
Anibal Ferreira dos Santos ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Breath Test ◽  
False Negative ◽  
Lateral Flow ◽  
Antigen Test ◽  
Kappa Index ◽  
Stool Antigen Test ◽  
Infection Diagnosis ◽  
Stool Antigen ◽  
H Pylori

The aim of this study was to validate the rapid lateral flow Helicobacter pylori stool antigen test (One step H. pylori antigen test, ACON laboratories, San Diego, USA; Prime diagnostics, São Paulo), using 13C-Urea Breath Test as the gold standard for H. pylori infection diagnosis. A total of 98 consecutive patients, asymptomatic or dyspeptic, entered the study. Sixty-nine were women, with a mean age of 45.76 ± 14.59 years (14 to 79 years). In the H. pylori-positive group, the rapid stool antigen test detected H. pylori antigen in 44 of the 50 positive patients (sensitivity 88%; 95% CI: 75.7-95.5%), and six false-negative; and in the H. pylori-negative group 42 presented negative results (specificity 87.5%; 95% CI: 74.7-95.3%), and six false-positive, showing a substantial agreement (Kappa Index = 0.75; p < 0.0001; 95% CI: 0.6-0.9). Forty four of fifty patients that had positive stool antigen were H. pylori-positive, the PPV of the stool antigen test was 88% (95% CI: 75.7-95.5%), and 42 patients with negative stool antigen test were H. pylori-negative, the NPV of the stool antigen test was 87.5% (95% CI: 74.7-95.3%). We conclude that the lateral flow stool antigen test can be used as an alternative to breath test for H. pylori infection diagnosis especially in developing countries.

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