scholarly journals Repeating Low-Positive Nucleic Acid Amplification Test Results for Chlamydia trachomatis and Neisseria gonorrhoeae: Assessment of Current Practice in Selected California Public- and Private-Sector Laboratories

2011 ◽  
Vol 50 (2) ◽  
pp. 539-539 ◽  
Author(s):  
J. M. Chow ◽  
H. M. Bauer ◽  
G. Bolan
2014 ◽  
Vol 53 (1) ◽  
pp. 327-328 ◽  
Author(s):  
Collette Bromhead ◽  
Nadika Liyanarachchy ◽  
Julia Mayes ◽  
Arlo Upton ◽  
Michelle Balm

Weak-positiveNeisseria gonorrhoeaenucleic acid amplification test results are difficult to interpret. We show that the frequency of unconfirmedN. gonorrhoeaeresults from the cobas 4800 test rises exponentially after 38.0 cycles, where the likelihood of an unconfirmed result exceeds 29%. Supplementary testing of such samples should be avoided; instead, treatment should be based on clinical pretest probability.


2017 ◽  
Vol 28 (14) ◽  
pp. 1405-1409
Author(s):  
Alexei Belozorov ◽  
Olga Fedets ◽  
Tatjana Chastii ◽  
Elena Milutina ◽  
Oksana Sokol ◽  
...  

There are no accurate data regarding the prevalence of Chlamydia trachomatis infection in Ukraine. This study aims to estimate the prevalence in the northeastern region of the country through reviewing nucleic acid amplification test results in patients of medical institutions in the Kharkov region during 2014–2016. Samples from 6920 patients (5028 women and 1892 men) aged 12–76 years were tested. The overall positivity rate was 4.5% (95% CI 4.0–5.0): 3.9% (95% CI 3.4–4.5) in women and 6.1% (95% CI 5.1–7.3) in men. The highest prevalence was found in the 16–20 (8.5%, CI 6.3–11.4) and 21–25 (8.0%, CI 6.7–9.4) year age groups. The prevalence in men was higher than in women in all investigated groups. The results show the need for more attention to the prevention, diagnosis, and treatment of chlamydial infection in these age groups of women and men in this region.


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