scholarly journals Hepatitis C Virus Core Mutations Reduce the Sensitivity of a Fluorescence Enzyme Immunoassay

2000 ◽  
Vol 38 (9) ◽  
pp. 3450-3452 ◽  
Author(s):  
Hajime Tokita ◽  
Gilbert R. Kaufmann ◽  
Mamoru Matsubayashi ◽  
Isao Okuda ◽  
Tsukasa Tanaka ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Enzyme Immunoassay ◽  
Core Region ◽  
Core Antigen ◽  
Nucleotide Sequencing ◽  
Hcv Rna ◽  
Virus Core ◽  
Hcv Core Antigen ◽  
Rna Levels

Four of 107 samples obtained from hepatitis C virus (HCV) carriers showed lower HCV core antigen levels in a fluorescence enzyme immunoassay (FEIA) than expected from corresponding HCV RNA levels. Nucleotide sequencing revealed a mutation in the HCV core region (Thr49Pro) that appears to have reduced the FEIA sensitivity.

scholarly journals Evaluation of a new enzyme immunoassay for hepatitis C virus(HCV) core antigen with clinical sensitivity approximating that of genomic amplification of HCV RNA

Hepatology ◽  
2000 ◽  
Vol 32 (2) ◽  
pp. 388-393 ◽  
Author(s):  
Eiji Tanaka ◽  
Chiharu Ohue ◽  
Katsumi Aoyagi ◽  
Kenjiro Yamaguchi ◽  
Shintaro Yagi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Enzyme Immunoassay ◽  
Core Antigen ◽  
Hcv Rna ◽  
Genomic Amplification ◽  
Clinical Sensitivity ◽  
Hcv Core Antigen

Isolate antibody to hepatitis C virus core antigen (C22) by RIBA-2: correlation with HCV-RNA and anti-NS5

1993 ◽  
pp. 219-228 ◽  
Author(s):  
G. Taliani ◽  
M. C. Badolato ◽  
R. Lecce ◽  
R. Bruni ◽  
C. Clementi ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Core Antigen ◽  
Hcv Rna ◽  
Virus Core

Amino acid substitutions in the hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by all-oral direct-acting antiviral regimens

2018 ◽  
Vol 90 (6) ◽  
pp. 1087-1093 ◽  
Author(s):  
Fumihiro Ogata ◽  
Norio Akuta ◽  
Masahiro Kobayashi ◽  
Shunichiro Fujiyama ◽  
Yusuke Kawamura ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Amino Acid ◽  
Core Region ◽  
Hcv Rna ◽  
Amino Acid Substitutions ◽  
Direct Acting Antiviral ◽  
Virus Core ◽  
Direct Acting

Amino acid substitutions in hepatitis C virus core region predict hepatocarcinogenesis following eradication of HCV RNA by antiviral therapy

2011 ◽  
Vol 83 (6) ◽  
pp. 1016-1022 ◽  
Author(s):  
Norio Akuta ◽  
Fumitaka Suzuki ◽  
Miharu Hirakawa ◽  
Yusuke Kawamura ◽  
Hitomi Sezaki ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Amino Acid ◽  
Antiviral Therapy ◽  
Core Region ◽  
Hcv Rna ◽  
Amino Acid Substitutions ◽  
Virus Core
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